JP6163162B2 - Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法 - Google Patents

Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法 Download PDF

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JP6163162B2
JP6163162B2 JP2014546471A JP2014546471A JP6163162B2 JP 6163162 B2 JP6163162 B2 JP 6163162B2 JP 2014546471 A JP2014546471 A JP 2014546471A JP 2014546471 A JP2014546471 A JP 2014546471A JP 6163162 B2 JP6163162 B2 JP 6163162B2
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lipocalin
lipocalin mutein
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アンドレアス ホールバウム
アンドレアス ホールバウム
ローレント オドリ
ローレント オドリ
ベヴァリー コラー
ベヴァリー コラー
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ピエリス ファーマシューティカルズ ゲーエムベーハー
ピエリス ファーマシューティカルズ ゲーエムベーハー
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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JP2014546471A 2011-12-13 2012-12-12 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法 Expired - Fee Related JP6163162B2 (ja)

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US201161570018P 2011-12-13 2011-12-13
US61/570,018 2011-12-13
PCT/EP2012/075146 WO2013087660A1 (en) 2011-12-13 2012-12-12 Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors

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JP2017067615A Division JP6725447B2 (ja) 2011-12-13 2017-03-30 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法

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JP2015505303A JP2015505303A (ja) 2015-02-19
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JP2014546471A Expired - Fee Related JP6163162B2 (ja) 2011-12-13 2012-12-12 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法
JP2017067615A Expired - Fee Related JP6725447B2 (ja) 2011-12-13 2017-03-30 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法
JP2019062186A Expired - Fee Related JP6889201B2 (ja) 2011-12-13 2019-03-28 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法
JP2020092168A Pending JP2020164532A (ja) 2011-12-13 2020-05-27 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法
JP2022049676A Active JP7441589B2 (ja) 2011-12-13 2022-03-25 Il-4および/またはil-13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法

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JP2017067615A Expired - Fee Related JP6725447B2 (ja) 2011-12-13 2017-03-30 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法
JP2019062186A Expired - Fee Related JP6889201B2 (ja) 2011-12-13 2019-03-28 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法
JP2020092168A Pending JP2020164532A (ja) 2011-12-13 2020-05-27 Il−4および/またはil−13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法
JP2022049676A Active JP7441589B2 (ja) 2011-12-13 2022-03-25 Il-4および/またはil-13のそれぞれの受容体への結合を阻害することによる特定の障害の予防または治療のための方法

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EP (3) EP3453400B1 (enExample)
JP (5) JP6163162B2 (enExample)
CN (2) CN109432402B (enExample)
AU (1) AU2012350660B2 (enExample)
CA (1) CA2858962C (enExample)
DK (2) DK3453400T3 (enExample)
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HU (2) HUE042720T2 (enExample)
PL (2) PL3453400T3 (enExample)
SG (2) SG10201604566QA (enExample)
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AU2011263786B2 (en) * 2010-06-08 2014-11-13 Astrazeneca Ab Tear lipocalin muteins binding IL-4 R alpha
EP3453400B1 (en) * 2011-12-13 2021-01-20 Pieris Pharmaceuticals GmbH Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors
EP3145945B1 (en) 2014-05-22 2020-07-15 Pieris Pharmaceuticals GmbH Novel specific-binding polypeptides and uses thereof
MX2018000447A (es) 2015-07-15 2018-08-15 Pieris Pharmaceuticals Gmbh Novedosas proteinas especificas para lag-3.
CN107474134B (zh) * 2016-06-08 2021-07-27 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
JP7225116B2 (ja) 2017-01-18 2023-02-20 ピエリス ファーマシューティカルズ ゲーエムベーハー Lag-3に対する結合親和性を有するリポカリンムテイン
JP7657548B2 (ja) 2017-04-21 2025-04-07 エランコ・ユーエス・インコーポレイテッド 獣医学的使用のためのil4/il13受容体分子
CN111494626B (zh) 2018-12-25 2022-06-21 江苏荃信生物医药股份有限公司 用于治疗il-4和/或il-13介导的信号转导相关的疾病的药物组合物
CN113939307A (zh) 2019-03-29 2022-01-14 皮里斯制药有限公司 脂质运载蛋白突变蛋白的吸入施用
EP3946415A1 (en) * 2019-03-29 2022-02-09 Astrazeneca AB Lipocalin mutein for treatment of asthma
MX2023007174A (es) 2020-12-18 2023-09-08 Astrazeneca Ab Formulacion de polvo seco de muteina de lipocalina para el tratamiento del asma.
CN115414467B (zh) * 2022-10-14 2023-06-06 中国人民解放军陆军军医大学第二附属医院 载脂蛋白d在制备治疗脑出血药物中的用途

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PL3453400T3 (pl) 2021-08-09
JP2022084854A (ja) 2022-06-07
EP3453400A1 (en) 2019-03-13
CN103998053A (zh) 2014-08-20
US10016483B2 (en) 2018-07-10
JP6725447B2 (ja) 2020-07-15
US20210145934A1 (en) 2021-05-20
DK3453400T3 (da) 2021-04-06
US20140357548A1 (en) 2014-12-04
CN103998053B (zh) 2018-11-02
JP2019116499A (ja) 2019-07-18
CN109432402B (zh) 2022-04-29
EP3842058A1 (en) 2021-06-30
SG10201604566QA (en) 2016-07-28
US20230021168A1 (en) 2023-01-19
EP2790719B1 (en) 2018-11-21
AU2012350660B2 (en) 2018-01-25
US10398754B2 (en) 2019-09-03
US11382951B2 (en) 2022-07-12
US20200009223A1 (en) 2020-01-09
TR201901826T4 (tr) 2019-03-21
ES2710384T3 (es) 2019-04-24
CN103998053B9 (zh) 2020-07-21
WO2013087660A1 (en) 2013-06-20
HUE054342T2 (hu) 2021-08-30
US9572863B2 (en) 2017-02-21
JP2017149733A (ja) 2017-08-31
US10857202B2 (en) 2020-12-08
JP7441589B2 (ja) 2024-03-01
EP2790719A1 (en) 2014-10-22
EP3453400B1 (en) 2021-01-20
PL2790719T3 (pl) 2019-05-31
JP2020164532A (ja) 2020-10-08
CA2858962A1 (en) 2013-06-20
AU2012350660A1 (en) 2014-07-03
CN109432402A (zh) 2019-03-08
US20170112900A1 (en) 2017-04-27
SG11201402992SA (en) 2014-07-30
HUE042720T2 (hu) 2019-07-29
JP2015505303A (ja) 2015-02-19
US20190030121A1 (en) 2019-01-31
DK2790719T3 (en) 2019-02-11
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ES2863410T3 (es) 2021-10-11
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