TR201819564T4 - Cmt ve ilgili bozuklukların tedavisi için yeni terapötik yaklaşımlar. - Google Patents
Cmt ve ilgili bozuklukların tedavisi için yeni terapötik yaklaşımlar.Info
- Publication number
- TR201819564T4 TR201819564T4 TR2018/19564T TR201819564T TR201819564T4 TR 201819564 T4 TR201819564 T4 TR 201819564T4 TR 2018/19564 T TR2018/19564 T TR 2018/19564T TR 201819564 T TR201819564 T TR 201819564T TR 201819564 T4 TR201819564 T4 TR 201819564T4
- Authority
- TR
- Turkey
- Prior art keywords
- related disorders
- cmt
- treatment
- novel therapeutic
- therapeutic approaches
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Abstract
Mevcut buluş, Charcot-Marie-Tooth hastalığı ve ilgili bozuklukların tedavisi için bileşimlerle ve yöntemlerle ilgilidir. Daha spesifik olarak, buluş söz konusu hastalığın sujede PMP22 ekspresyonunun azaltılması aracılığıyla tedavi edilmesi için kombine tedavilerle ilgilidir.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07301614A EP2065038A1 (en) | 2007-11-30 | 2007-11-30 | New therapeutic approaches for treating Charcot-Marie-Tooth disease |
US99180007P | 2007-12-03 | 2007-12-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201819564T4 true TR201819564T4 (tr) | 2019-01-21 |
Family
ID=39264515
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2018/19564T TR201819564T4 (tr) | 2007-11-30 | 2008-11-28 | Cmt ve ilgili bozuklukların tedavisi için yeni terapötik yaklaşımlar. |
Country Status (24)
Country | Link |
---|---|
US (6) | US8992891B2 (tr) |
EP (4) | EP2065038A1 (tr) |
JP (4) | JP5953000B2 (tr) |
KR (1) | KR101546031B1 (tr) |
CN (2) | CN101883561B (tr) |
AU (1) | AU2008328745B2 (tr) |
BR (1) | BRPI0819678A2 (tr) |
CA (3) | CA3031484C (tr) |
CY (2) | CY1113980T1 (tr) |
DK (2) | DK2211846T3 (tr) |
EA (3) | EA032767B1 (tr) |
ES (3) | ES2703508T3 (tr) |
HR (2) | HRP20130345T1 (tr) |
HU (1) | HUE040596T2 (tr) |
IL (1) | IL205741A0 (tr) |
LT (1) | LT2609916T (tr) |
MX (1) | MX2010005709A (tr) |
NZ (1) | NZ585440A (tr) |
PL (2) | PL2211846T3 (tr) |
PT (2) | PT2211846E (tr) |
SI (2) | SI2211846T1 (tr) |
TR (1) | TR201819564T4 (tr) |
WO (1) | WO2009068668A1 (tr) |
ZA (1) | ZA201003610B (tr) |
Families Citing this family (32)
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EP2065038A1 (en) | 2007-11-30 | 2009-06-03 | Pharnext | New therapeutic approaches for treating Charcot-Marie-Tooth disease |
EP2135607A1 (en) * | 2008-06-18 | 2009-12-23 | Pharnext | Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders |
WO2010025322A2 (en) * | 2008-08-28 | 2010-03-04 | The Florida International University Board Of Trustees | Magnetic nanodelivery of therapeutic agents across the blood brain barrier |
EP2263665A1 (en) | 2009-06-02 | 2010-12-22 | Pharnext | New compositions for treating CMT and related disorders |
US9393241B2 (en) | 2009-06-02 | 2016-07-19 | Pharnext | Compositions for treating CMT and related disorders |
WO2011061304A1 (en) * | 2009-11-20 | 2011-05-26 | Pharnext | New diagnostic tools for charcot-marie-tooth disease |
EP2523661B1 (en) | 2010-01-15 | 2017-05-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Nkcc inhibitors for the treatment of autism |
WO2012045804A1 (en) * | 2010-10-08 | 2012-04-12 | Vib Vzw | Hdac inhibitors to treat charcot-marie-tooth disease |
CN102464610B (zh) * | 2010-11-16 | 2014-07-30 | 北大方正集团有限公司 | 一种美替拉酮的制备方法 |
ES2716865T3 (es) | 2011-02-18 | 2019-06-17 | Scripps Research Inst | Diferenciación dirigida de células precursoras de oligodendrocitos a un destino celular mielinizante |
RU2013139247A (ru) | 2011-02-23 | 2015-03-27 | Церулеус Лтд. | Комплексы флумазенила, содержащие их композиции и их применения |
UA115968C2 (uk) | 2011-03-01 | 2018-01-25 | Фарнекст | Нові композиції для лікування неврологічних захворювань |
US9248111B2 (en) | 2011-03-01 | 2016-02-02 | Pharnext | Therapeutic approaches for treating parkinson's disease |
EP2705842A1 (en) | 2012-09-05 | 2014-03-12 | Pharnext | Therapeutic approaches for treating parkinson's disease |
CN102247324B (zh) * | 2011-07-14 | 2012-11-21 | 海南美兰史克制药有限公司 | 一种氟马西尼脂质体注射液 |
CN102887830B (zh) * | 2012-09-04 | 2013-11-27 | 苏州弘森药业有限公司 | 一种盐酸酚苄明的制备方法 |
US10016142B2 (en) | 2012-10-19 | 2018-07-10 | Sidewaystrategies Llc | Systems and methods for nerve mapping and monitoring |
US20150329483A1 (en) * | 2012-12-17 | 2015-11-19 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and Pharmaceutical Compositions for the Treatment of X-Linked Charcot-Marie-Tooth |
SI3003268T1 (sl) | 2013-06-05 | 2019-01-31 | Pharnext | Stabilne oralne raztopine za kombinirane API |
JP6619744B2 (ja) | 2014-02-11 | 2019-12-11 | ファーネクストPharnext | 神経障害の処置のためのバクロフェン、アカンプロセート、及び中鎖トリグリセライドの併用 |
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US10383870B2 (en) | 2016-06-10 | 2019-08-20 | Pharnext | Early treatment of CMT disease |
US11272871B2 (en) | 2016-07-14 | 2022-03-15 | Sidewaystrategies Llc | System and methods for improving diagnostic evoked potential studies for functional assessments of nerves and nerve pathways |
CA3044691A1 (en) | 2016-10-26 | 2018-05-03 | Genea Biocells USA (Holdings), Inc. | Improved generation of muscle lineage cells and therapeutic uses thereof |
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2007
- 2007-11-30 EP EP07301614A patent/EP2065038A1/en not_active Withdrawn
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2008
- 2008-11-28 PL PL08854467T patent/PL2211846T3/pl unknown
- 2008-11-28 KR KR1020107014240A patent/KR101546031B1/ko active IP Right Grant
- 2008-11-28 EP EP18203488.4A patent/EP3459535B1/en active Active
- 2008-11-28 SI SI200830954T patent/SI2211846T1/sl unknown
- 2008-11-28 DK DK08854467.1T patent/DK2211846T3/da active
- 2008-11-28 ES ES12196650T patent/ES2703508T3/es active Active
- 2008-11-28 EP EP12196650.1A patent/EP2609916B1/en active Active
- 2008-11-28 ES ES18203488T patent/ES2831855T3/es active Active
- 2008-11-28 EA EA201301078A patent/EA032767B1/ru not_active IP Right Cessation
- 2008-11-28 PT PT88544671T patent/PT2211846E/pt unknown
- 2008-11-28 CN CN200880118498.4A patent/CN101883561B/zh active Active
- 2008-11-28 NZ NZ585440A patent/NZ585440A/en unknown
- 2008-11-28 EA EA201000914A patent/EA019402B1/ru not_active IP Right Cessation
- 2008-11-28 CA CA3031484A patent/CA3031484C/en active Active
- 2008-11-28 PL PL12196650T patent/PL2609916T3/pl unknown
- 2008-11-28 BR BRPI0819678A patent/BRPI0819678A2/pt not_active Application Discontinuation
- 2008-11-28 US US12/744,962 patent/US8992891B2/en active Active
- 2008-11-28 DK DK12196650.1T patent/DK2609916T3/en active
- 2008-11-28 CN CN201410322856.0A patent/CN104257657B/zh active Active
- 2008-11-28 TR TR2018/19564T patent/TR201819564T4/tr unknown
- 2008-11-28 CA CA3031490A patent/CA3031490C/en active Active
- 2008-11-28 CA CA2705408A patent/CA2705408C/en active Active
- 2008-11-28 HU HUE12196650A patent/HUE040596T2/hu unknown
- 2008-11-28 MX MX2010005709A patent/MX2010005709A/es active IP Right Grant
- 2008-11-28 ES ES08854467T patent/ES2408785T3/es active Active
- 2008-11-28 JP JP2010535399A patent/JP5953000B2/ja active Active
- 2008-11-28 LT LTEP12196650.1T patent/LT2609916T/lt unknown
- 2008-11-28 SI SI200832028T patent/SI2609916T1/sl unknown
- 2008-11-28 PT PT12196650T patent/PT2609916T/pt unknown
- 2008-11-28 EP EP08854467A patent/EP2211846B1/en active Active
- 2008-11-28 EA EA201791669A patent/EA035711B1/ru not_active IP Right Cessation
- 2008-11-28 AU AU2008328745A patent/AU2008328745B2/en active Active
- 2008-11-28 WO PCT/EP2008/066468 patent/WO2009068668A1/en active Application Filing
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2010
- 2010-05-13 IL IL205741A patent/IL205741A0/en active IP Right Grant
- 2010-05-21 ZA ZA2010/03610A patent/ZA201003610B/en unknown
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2013
- 2013-04-17 HR HRP20130345AT patent/HRP20130345T1/hr unknown
- 2013-05-02 CY CY20131100368T patent/CY1113980T1/el unknown
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2015
- 2015-02-20 US US14/627,229 patent/US20150157626A1/en not_active Abandoned
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2016
- 2016-03-01 JP JP2016039032A patent/JP6608309B2/ja active Active
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2018
- 2018-02-26 JP JP2018031658A patent/JP2018109043A/ja active Pending
- 2018-04-30 US US15/966,848 patent/US10322101B2/en active Active
- 2018-08-06 US US16/055,710 patent/US10441558B2/en active Active
- 2018-08-06 US US16/055,797 patent/US10463640B2/en active Active
- 2018-12-18 HR HRP20182147TT patent/HRP20182147T8/hr unknown
- 2018-12-19 CY CY20181101374T patent/CY1121183T1/el unknown
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2019
- 2019-04-17 JP JP2019078588A patent/JP2019142917A/ja active Pending
- 2019-09-27 US US16/586,136 patent/US20200155491A1/en not_active Abandoned
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