HRP20182147T8 - Novi terapijski pristupi za liječenje cmt-a i srodnih poremećaja - Google Patents

Novi terapijski pristupi za liječenje cmt-a i srodnih poremećaja

Info

Publication number
HRP20182147T8
HRP20182147T8 HRP20182147TT HRP20182147T HRP20182147T8 HR P20182147 T8 HRP20182147 T8 HR P20182147T8 HR P20182147T T HRP20182147T T HR P20182147TT HR P20182147 T HRP20182147 T HR P20182147T HR P20182147 T8 HRP20182147 T8 HR P20182147T8
Authority
HR
Croatia
Prior art keywords
related disorders
new therapeutic
therapeutic approaches
treating cmt
cmt
Prior art date
Application number
HRP20182147TT
Other languages
English (en)
Inventor
Daniel Cohen
Ilya Chumakov
Oxana Guerassimenko
Serguei Nabirochkin
Original Assignee
Pharnext
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharnext filed Critical Pharnext
Publication of HRP20182147T1 publication Critical patent/HRP20182147T1/hr
Publication of HRP20182147T8 publication Critical patent/HRP20182147T8/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
HRP20182147TT 2007-11-30 2018-12-18 Novi terapijski pristupi za liječenje cmt-a i srodnih poremećaja HRP20182147T8 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07301614A EP2065038A1 (en) 2007-11-30 2007-11-30 New therapeutic approaches for treating Charcot-Marie-Tooth disease
US99180007P 2007-12-03 2007-12-03
EP12196650.1A EP2609916B1 (en) 2007-11-30 2008-11-28 New therapeutic approaches for treating CMT and related disorders

Publications (2)

Publication Number Publication Date
HRP20182147T1 HRP20182147T1 (hr) 2019-03-08
HRP20182147T8 true HRP20182147T8 (hr) 2019-04-19

Family

ID=39264515

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20130345AT HRP20130345T1 (hr) 2007-11-30 2013-04-17 NOVI TERAPIJSKI PRISTUPI ZA LIJEČENJE CMT-a I SRODNIH POREMEĆA
HRP20182147TT HRP20182147T8 (hr) 2007-11-30 2018-12-18 Novi terapijski pristupi za liječenje cmt-a i srodnih poremećaja

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HRP20130345AT HRP20130345T1 (hr) 2007-11-30 2013-04-17 NOVI TERAPIJSKI PRISTUPI ZA LIJEČENJE CMT-a I SRODNIH POREMEĆA

Country Status (24)

Country Link
US (6) US8992891B2 (hr)
EP (4) EP2065038A1 (hr)
JP (4) JP5953000B2 (hr)
KR (1) KR101546031B1 (hr)
CN (2) CN101883561B (hr)
AU (1) AU2008328745B2 (hr)
BR (1) BRPI0819678A2 (hr)
CA (3) CA3031484C (hr)
CY (2) CY1113980T1 (hr)
DK (2) DK2211846T3 (hr)
EA (3) EA032767B1 (hr)
ES (3) ES2703508T3 (hr)
HR (2) HRP20130345T1 (hr)
HU (1) HUE040596T2 (hr)
IL (1) IL205741A0 (hr)
LT (1) LT2609916T (hr)
MX (1) MX2010005709A (hr)
NZ (1) NZ585440A (hr)
PL (2) PL2211846T3 (hr)
PT (2) PT2211846E (hr)
SI (2) SI2211846T1 (hr)
TR (1) TR201819564T4 (hr)
WO (1) WO2009068668A1 (hr)
ZA (1) ZA201003610B (hr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2065038A1 (en) 2007-11-30 2009-06-03 Pharnext New therapeutic approaches for treating Charcot-Marie-Tooth disease
EP2135607A1 (en) * 2008-06-18 2009-12-23 Pharnext Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders
WO2010025322A2 (en) * 2008-08-28 2010-03-04 The Florida International University Board Of Trustees Magnetic nanodelivery of therapeutic agents across the blood brain barrier
EP2263665A1 (en) 2009-06-02 2010-12-22 Pharnext New compositions for treating CMT and related disorders
US9393241B2 (en) 2009-06-02 2016-07-19 Pharnext Compositions for treating CMT and related disorders
WO2011061304A1 (en) * 2009-11-20 2011-05-26 Pharnext New diagnostic tools for charcot-marie-tooth disease
EP2523661B1 (en) 2010-01-15 2017-05-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Nkcc inhibitors for the treatment of autism
WO2012045804A1 (en) * 2010-10-08 2012-04-12 Vib Vzw Hdac inhibitors to treat charcot-marie-tooth disease
CN102464610B (zh) * 2010-11-16 2014-07-30 北大方正集团有限公司 一种美替拉酮的制备方法
ES2716865T3 (es) 2011-02-18 2019-06-17 Scripps Research Inst Diferenciación dirigida de células precursoras de oligodendrocitos a un destino celular mielinizante
RU2013139247A (ru) 2011-02-23 2015-03-27 Церулеус Лтд. Комплексы флумазенила, содержащие их композиции и их применения
UA115968C2 (uk) 2011-03-01 2018-01-25 Фарнекст Нові композиції для лікування неврологічних захворювань
US9248111B2 (en) 2011-03-01 2016-02-02 Pharnext Therapeutic approaches for treating parkinson's disease
EP2705842A1 (en) 2012-09-05 2014-03-12 Pharnext Therapeutic approaches for treating parkinson's disease
CN102247324B (zh) * 2011-07-14 2012-11-21 海南美兰史克制药有限公司 一种氟马西尼脂质体注射液
CN102887830B (zh) * 2012-09-04 2013-11-27 苏州弘森药业有限公司 一种盐酸酚苄明的制备方法
US10016142B2 (en) 2012-10-19 2018-07-10 Sidewaystrategies Llc Systems and methods for nerve mapping and monitoring
US20150329483A1 (en) * 2012-12-17 2015-11-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and Pharmaceutical Compositions for the Treatment of X-Linked Charcot-Marie-Tooth
SI3003268T1 (sl) 2013-06-05 2019-01-31 Pharnext Stabilne oralne raztopine za kombinirane API
JP6619744B2 (ja) 2014-02-11 2019-12-11 ファーネクストＰｈａｒｎｅｘｔ 神経障害の処置のためのバクロフェン、アカンプロセート、及び中鎖トリグリセライドの併用
CN106456571B (zh) * 2014-02-24 2021-07-27 法奈科斯公司 用于治疗机械性神经元损伤的组合物
US20160339015A1 (en) * 2015-05-20 2016-11-24 Lupin Inc. Oral pharmaceutical composition of methylergonovine
EP3426349A4 (en) 2016-03-09 2020-01-01 Ionis Pharmaceuticals, Inc. METHODS AND COMPOSITIONS FOR INHIBITING PMP22 EXPRESSION
US10383870B2 (en) 2016-06-10 2019-08-20 Pharnext Early treatment of CMT disease
US11272871B2 (en) 2016-07-14 2022-03-15 Sidewaystrategies Llc System and methods for improving diagnostic evoked potential studies for functional assessments of nerves and nerve pathways
CA3044691A1 (en) 2016-10-26 2018-05-03 Genea Biocells USA (Holdings), Inc. Improved generation of muscle lineage cells and therapeutic uses thereof
CA3071114A1 (en) 2017-07-28 2019-01-31 Applied Therapeutics Inc. Compositions and methods for treating galactosemia
MX2021013511A (es) * 2019-05-07 2022-02-23 Univ Miami Tratamiento y deteccion de neuropatias heredadas y trastornos asociados.
CA3176768A1 (en) * 2020-05-01 2021-11-04 Shoshana SHENDELMAN Aldose reductase inhibitors for treating sorbitol dehydrogenase deficiency
EP4019016A1 (en) * 2020-12-24 2022-06-29 Allaysis, LLC Methods of administering intravenous baclofen
US11523984B1 (en) * 2021-11-12 2022-12-13 Amneal Pharmaceuticals Llc Compositions and methods of administering baclofen
WO2023182288A1 (ja) * 2022-03-22 2023-09-28 国立大学法人京都大学 シャルコー・マリー・ツース病の治療または予防薬

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW427904B (en) 1995-12-07 2001-04-01 American Home Prod Neuroprotective agents
RU2184570C2 (ru) 1997-09-30 2002-07-10 Дайити Фармасьютикал Ко., Лтд. Препараты для орального введения
CA2345642A1 (en) 1998-10-02 2000-04-13 Celtrix Pharmaceuticals, Inc. Methods for the treatment of non-thyroid disorders
JP2004504002A (ja) * 1999-01-19 2004-02-12 インサイト・ファーマスーティカルズ・インコーポレイテッド ヒトシャペロンタンパク質
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
WO2002049607A2 (en) 2000-12-20 2002-06-27 Firmenich Sa Flavoured oral drug delivery system
JP3805646B2 (ja) 2001-05-25 2006-08-02 久光メディカル株式会社 医薬液剤
DE60237372D1 (de) * 2001-07-04 2010-09-30 Sun Pharma Advanced Res Co Ltd Magenretentionssystem mit kontrollierter arzneimittelfreisetzung
MXPA04008772A (es) * 2002-03-14 2004-12-06 Euro Celtique Sa Composiciones de clorhidrato de naltrexona.
PT1578350E (pt) * 2002-03-26 2009-08-27 Euro Celtique Sa Composições revestidas com geles de libertação constante
FR2842422B1 (fr) 2002-07-16 2006-06-30 Univ Aix Marseille Ii Compositions destinees au traitement des neuropathies peripheriques, preparation et utilisations
JP2004049093A (ja) * 2002-07-18 2004-02-19 Meiji Milk Prod Co Ltd 腸内酪酸上昇食品組成物および医薬品
WO2004019938A1 (en) 2002-08-28 2004-03-11 Merck Frosst Canada & Co. Oxazolidin-2-one and thiazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of glaucoma
RU2224518C1 (ru) * 2003-02-10 2004-02-27 Дулькис Мария Дмитриевна Жидкая лекарственная форма налтрексона
CA2516816C (en) * 2003-02-24 2012-02-07 Pharmaceutical Productions, Inc. Transmucosal drug delivery system
WO2004091623A1 (en) * 2003-04-08 2004-10-28 Progenics Pharmaceuticals. Inc. Pharmaceutical formulations containing methylnaltrexone
WO2004091593A2 (en) * 2003-04-14 2004-10-28 Pain Therapeutics, Inc. Methods for the treatment of pain comprising opioid antagonists
WO2004103263A2 (en) 2003-05-22 2004-12-02 Yeda Research And Development Co. Ltd. Dopamine and agonists and antagonists thereof for treatment of neurodegenerative diseases
PT1663229E (pt) 2003-09-25 2010-07-13 Euro Celtique Sa CombinaãŽes farmac—uticas de hidrocodona e naltrexona
CA2537029C (en) 2003-11-26 2013-03-12 Likan Liang Micellar systems useful for delivery of lipophilic or hydrophobic compounds
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
US20050220863A1 (en) 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist
JP2006131545A (ja) 2004-11-05 2006-05-25 Japan Science & Technology Agency 神経因性疼痛治療剤
GB0509052D0 (en) * 2005-05-04 2005-06-08 Aimsco Ltd Combination therapy
US20070099947A1 (en) 2005-11-03 2007-05-03 Alkermes, Inc. Methods and compositions for the treatment of brain reward system disorders by combination therapy
DE102006016990A1 (de) * 2006-04-11 2007-10-18 Hermann, Holger Lars, Dr. Verwendung von Baclofen und Baclofen-Derivaten zur Entzugs- und/oder Substitutionsbehandlung bei Abhängigkeit von GHB und/oder GHB-Analogen
US7678808B2 (en) * 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
EP2382975A3 (en) * 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
CA2674610C (en) 2007-01-11 2013-06-18 Xenoport, Inc. Sustained release oral dosage forms of a prodrug of r-baclofen and methods of treatment
US20080255062A1 (en) 2007-02-13 2008-10-16 University Of Manitoba Axon regeneration from adult sensory neurons
US7806721B2 (en) * 2007-08-02 2010-10-05 Tyco Electronics Corporation Patch panel modular jack assembly
EP2065038A1 (en) 2007-11-30 2009-06-03 Pharnext New therapeutic approaches for treating Charcot-Marie-Tooth disease
EP2135607A1 (en) 2008-06-18 2009-12-23 Pharnext Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders
US9393241B2 (en) 2009-06-02 2016-07-19 Pharnext Compositions for treating CMT and related disorders
EP2263665A1 (en) * 2009-06-02 2010-12-22 Pharnext New compositions for treating CMT and related disorders
EP2322163A1 (en) 2009-11-03 2011-05-18 Pharnext New therapeutics approaches for treating alzheimer disease
IT1400067B1 (it) 2010-05-21 2013-05-17 Molteni & C Spray nasale liquido contenente naltrexone a bassi dosaggi.
CN105997969B (zh) 2011-03-01 2022-03-25 法耐斯特公司 基于巴氯芬和阿坎酸的神经性障碍疗法
US9931326B2 (en) 2011-03-29 2018-04-03 Pharnext Composition comprising torasemide and baclofen for treating neurological disorders
SI3003268T1 (sl) 2013-06-05 2019-01-31 Pharnext Stabilne oralne raztopine za kombinirane API
US10383870B2 (en) 2016-06-10 2019-08-20 Pharnext Early treatment of CMT disease

Also Published As

Publication number Publication date
US10322101B2 (en) 2019-06-18
SI2211846T1 (sl) 2013-07-31
JP2016145227A (ja) 2016-08-12
CA3031484A1 (en) 2009-06-04
PT2211846E (pt) 2013-05-10
EP2609916B1 (en) 2018-11-07
EA035711B1 (ru) 2020-07-29
US20180250289A1 (en) 2018-09-06
HRP20182147T1 (hr) 2019-03-08
EA201301078A1 (ru) 2014-06-30
CN104257657B (zh) 2017-07-04
JP6608309B2 (ja) 2019-11-20
US20180360785A1 (en) 2018-12-20
ZA201003610B (en) 2011-06-29
ES2831855T3 (es) 2021-06-09
EP3459535B1 (en) 2020-08-12
PL2609916T3 (pl) 2019-03-29
PL2211846T3 (pl) 2013-09-30
SI2609916T1 (sl) 2019-03-29
EP2211846B1 (en) 2013-02-27
KR20100088160A (ko) 2010-08-06
CN101883561B (zh) 2014-07-30
EA201791669A2 (ru) 2017-12-29
ES2703508T3 (es) 2019-03-11
US20200155491A1 (en) 2020-05-21
TR201819564T4 (tr) 2019-01-21
EP2065038A1 (en) 2009-06-03
US20180338969A1 (en) 2018-11-29
HRP20130345T1 (hr) 2013-07-31
IL205741A0 (en) 2010-11-30
EA201000914A1 (ru) 2010-12-30
DK2609916T3 (en) 2019-01-21
KR101546031B1 (ko) 2015-08-25
HUE040596T2 (hu) 2019-03-28
BRPI0819678A2 (pt) 2017-05-09
EP3459535A1 (en) 2019-03-27
EA019402B1 (ru) 2014-03-31
US20100310641A1 (en) 2010-12-09
JP2018109043A (ja) 2018-07-12
JP2019142917A (ja) 2019-08-29
PT2609916T (pt) 2019-01-10
CA3031490C (en) 2021-05-04
CA3031490A1 (en) 2009-06-04
DK2211846T3 (da) 2013-04-29
US20150157626A1 (en) 2015-06-11
ES2408785T3 (es) 2013-06-21
LT2609916T (lt) 2019-02-11
CA2705408C (en) 2019-04-23
EA201791669A3 (ru) 2018-03-30
US8992891B2 (en) 2015-03-31
EP2211846A1 (en) 2010-08-04
JP5953000B2 (ja) 2016-07-13
AU2008328745B2 (en) 2014-01-30
CA3031484C (en) 2021-05-04
MX2010005709A (es) 2010-11-05
CY1121183T1 (el) 2020-05-29
EP2609916A1 (en) 2013-07-03
JP2011504915A (ja) 2011-02-17
CN104257657A (zh) 2015-01-07
CY1113980T1 (el) 2016-07-27
CA2705408A1 (en) 2009-06-04
AU2008328745A1 (en) 2009-06-04
WO2009068668A1 (en) 2009-06-04
US10463640B2 (en) 2019-11-05
CN101883561A (zh) 2010-11-10
EA032767B1 (ru) 2019-07-31
NZ585440A (en) 2011-12-22
US10441558B2 (en) 2019-10-15

Similar Documents

Publication Publication Date Title
HRP20182147T8 (hr) Novi terapijski pristupi za liječenje cmt-a i srodnih poremećaja
HK1259102A1 (zh) 用於治療微生物病症的amp
ZA200900734B (en) Combination treatment for metabolic disorders
EP2170309A4 (en) METHOD AND COMPOSITIONS FOR THE TREATMENT OF DISEASES
GB0602178D0 (en) Therapeutic treatment
ZA201003497B (en) Methods for treating obesity and obesity related diseases and disorders
HK1158172A1 (en) Compounds for treating ophthalmic diseases and disorders
EP2083857A4 (en) METHOD FOR TREATING INTERFERENCE IN CONNECTION WITH MICA
HK1206590A1 (en) New compositions for treating cmt and related disorders
IL222557A (en) A compound for use in treating mutant disorders has ruled
EP2219448A4 (en) THERAPEUTIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASES AND SUFFERINGS
IL201422A0 (en) Therapeutic agents useful for treating pain
ZA201002167B (en) Treatment regime for proliferative disorders
GB0608655D0 (en) Therapeutic Treatment
GB0915259D0 (en) Sulphur-linked compounds for treating ophthalmic diseases and disorders
EP2120994A4 (en) METHOD AND COMPOSITIONS FOR TREATING HYPOGLYKEMIC CONDITIONS
PT2481407T (pt) Compostos para utilização no tratamento de distúrbios cognitivos
GB0610909D0 (en) Therapeutic treatment
GB0702537D0 (en) Treatment for excessive adiposity
PL1982178T3 (pl) Sposoby leczenia zaburzeń afektywnych
IL207906A0 (en) Treatment for ocular-related disorders
PT2278962E (pt) Métodos para o tratamento de desordens dermatológicas
EP2059238A4 (en) THERAPEUTIC COMPOUNDS FOR DISEASES AND DISORDERS
HK1145282A1 (en) Treatment of sleep disorders
GB0610376D0 (en) Therapeutic treatment