TR201816539T4 - Pomalidomidin hazırlanmasına ve saflaştırılmasına yönelik geliştirilmiş proses. - Google Patents

Pomalidomidin hazırlanmasına ve saflaştırılmasına yönelik geliştirilmiş proses. Download PDF

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Publication number
TR201816539T4
TR201816539T4 TR2018/16539T TR201816539T TR201816539T4 TR 201816539 T4 TR201816539 T4 TR 201816539T4 TR 2018/16539 T TR2018/16539 T TR 2018/16539T TR 201816539 T TR201816539 T TR 201816539T TR 201816539 T4 TR201816539 T4 TR 201816539T4
Authority
TR
Turkey
Prior art keywords
pomalidomide
dione
preparation
solvent
reaction
Prior art date
Application number
TR2018/16539T
Other languages
English (en)
Turkish (tr)
Inventor
Gore Vinayak
Kumar Shukla Vinay
Shinde Dhananjay
Prakash Bansode
Original Assignee
Mylan Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mylan Laboratories Ltd filed Critical Mylan Laboratories Ltd
Priority claimed from IN5409CH2013 external-priority patent/IN2013CH05409A/en
Publication of TR201816539T4 publication Critical patent/TR201816539T4/tr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
TR2018/16539T 2013-11-25 2014-11-24 Pomalidomidin hazırlanmasına ve saflaştırılmasına yönelik geliştirilmiş proses. TR201816539T4 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN424CH2014 2014-01-30
IN5409CH2013 IN2013CH05409A (enExample) 2013-11-25 2014-11-24

Publications (1)

Publication Number Publication Date
TR201816539T4 true TR201816539T4 (tr) 2018-11-21

Family

ID=52350154

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2018/16539T TR201816539T4 (tr) 2013-11-25 2014-11-24 Pomalidomidin hazırlanmasına ve saflaştırılmasına yönelik geliştirilmiş proses.

Country Status (9)

Country Link
US (1) US20160362391A1 (enExample)
EP (1) EP3074383B1 (enExample)
JP (1) JP6644685B2 (enExample)
AU (1) AU2014351354B2 (enExample)
BR (1) BR112016011700B1 (enExample)
CA (1) CA2931606A1 (enExample)
ES (1) ES2694512T3 (enExample)
TR (1) TR201816539T4 (enExample)
WO (1) WO2015075694A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104557858B (zh) * 2013-10-29 2018-06-01 上海医药工业研究院 一种泊利度胺的制备方法
HU231259B1 (hu) 2016-02-04 2022-06-28 Egyt Gyogyszervegyeszeti Gyar Eljárás pomalidomide elõállítására
CN105924426B (zh) * 2016-06-20 2019-03-08 浙江海正药业股份有限公司 一种泊马度胺的结晶工艺
CN105866297B (zh) * 2016-06-24 2019-01-04 合肥久诺医药科技有限公司 一种泊马度胺有关物质的高效液相色谱分析方法
CN106565668B (zh) * 2016-10-27 2020-01-10 扬子江药业集团有限公司 一种高纯度泊马度胺的制备方法
WO2018154516A1 (en) * 2017-02-23 2018-08-30 Sun Pharmaceutical Industries Limited Process for the preparation of pomalidomide
CN114605381A (zh) * 2020-12-03 2022-06-10 南京海辰药业股份有限公司 一种泊马度胺的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635517B1 (en) * 1996-07-24 1999-06-29 Celgene Corp Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
US6281230B1 (en) * 1996-07-24 2001-08-28 Celgene Corporation Isoindolines, method of use, and pharmaceutical compositions
US6660736B2 (en) * 2002-03-27 2003-12-09 Hoffmann-La Roche Inc. Phthalimido derivatives and a process for their preparation
DK1907373T3 (da) * 2005-06-30 2013-02-04 Celgene Corp Fremgangsmåder til fremstillingen af 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dionforbindelser
MX2013005434A (es) * 2010-11-18 2013-09-26 Deuteria Pharmaceuticals Inc 3´ - deutero - polidomida.
WO2012177678A2 (en) * 2011-06-22 2012-12-27 Celgene Corporation Isotopologues of pomalidomide
WO2013126326A1 (en) * 2012-02-21 2013-08-29 Celgene Corporation Solid forms of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, compositions and methods of use thereof
EP2981532A4 (en) * 2013-04-01 2016-12-14 Hetero Research Foundation PROCESS FOR THE PREPARATION OF POMALIDOMIDE
CN103288797B (zh) * 2013-05-17 2016-03-02 宁波百思佳医药科技有限公司 一种用亚砜类溶剂纯化Pomalidomide的方法
CN103275062B (zh) * 2013-05-17 2016-04-13 宁波百思佳医药科技有限公司 一种Pomalidomide的纯化方法

Also Published As

Publication number Publication date
AU2014351354B2 (en) 2018-11-08
EP3074383A1 (en) 2016-10-05
JP6644685B2 (ja) 2020-02-12
AU2014351354A1 (en) 2016-06-16
BR112016011700A2 (pt) 2017-10-10
US20160362391A1 (en) 2016-12-15
CA2931606A1 (en) 2015-05-28
BR112016011700B1 (pt) 2022-08-23
WO2015075694A1 (en) 2015-05-28
ES2694512T3 (es) 2018-12-21
JP2017505286A (ja) 2017-02-16
EP3074383B1 (en) 2018-10-10

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