TR201808197T4 - Mikroemülsiyon topikal dağıtım platformu. - Google Patents

Mikroemülsiyon topikal dağıtım platformu. Download PDF

Info

Publication number
TR201808197T4
TR201808197T4 TR2018/08197T TR201808197T TR201808197T4 TR 201808197 T4 TR201808197 T4 TR 201808197T4 TR 2018/08197 T TR2018/08197 T TR 2018/08197T TR 201808197 T TR201808197 T TR 201808197T TR 201808197 T4 TR201808197 T4 TR 201808197T4
Authority
TR
Turkey
Prior art keywords
surfactant
eye
water
oil
microemulsion
Prior art date
Application number
TR2018/08197T
Other languages
English (en)
Turkish (tr)
Inventor
A Wassel Ronald
George Mondalek Fadee
Rafal Farjo A
Alexander Quiambao B
Didier Nuno J
Original Assignee
Eyecro Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eyecro Llc filed Critical Eyecro Llc
Publication of TR201808197T4 publication Critical patent/TR201808197T4/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TR2018/08197T 2013-03-14 2014-03-13 Mikroemülsiyon topikal dağıtım platformu. TR201808197T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361784005P 2013-03-14 2013-03-14

Publications (1)

Publication Number Publication Date
TR201808197T4 true TR201808197T4 (tr) 2018-07-23

Family

ID=50628949

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2018/08197T TR201808197T4 (tr) 2013-03-14 2014-03-13 Mikroemülsiyon topikal dağıtım platformu.

Country Status (12)

Country Link
US (2) US8968775B2 (enExample)
EP (1) EP2968139B1 (enExample)
JP (1) JP6348567B2 (enExample)
CN (1) CN105451718B (enExample)
AU (1) AU2014244154B2 (enExample)
CA (1) CA2905023C (enExample)
DK (1) DK2968139T3 (enExample)
ES (1) ES2673009T3 (enExample)
PL (1) PL2968139T3 (enExample)
PT (1) PT2968139T (enExample)
TR (1) TR201808197T4 (enExample)
WO (1) WO2014160079A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2448494T3 (es) 2006-07-13 2014-03-14 Achillion Pharmaceuticals, Inc. Péptidos de 4-amino-4-oxobutanoilo en calidad de inhibidores de la replicación viral
ES2584534B1 (es) * 2015-03-27 2017-03-13 Retinset, S.L. Formulación tópica oftálmica de bosentan
WO2017127306A1 (en) 2016-01-18 2017-07-27 Arisan Therapeutics Adamatane derivatives for the treatment of filovirus infection
DK3266446T3 (en) * 2016-07-07 2019-02-11 Salvat Lab Sa Eye preparation comprising castor oil and medium chain triglyceride
US11548893B2 (en) 2017-07-15 2023-01-10 Arisan Therapeutics Inc. Enantiomerically pure adamantane carboxamides for the treatment of filovirus infection
KR102652605B1 (ko) * 2017-08-27 2024-03-28 로드스 테크놀로지즈 안과 질환 치료를 위한 약학제적 조성물
US11583497B2 (en) 2017-11-14 2023-02-21 The Schepens Eye Research Institute, Inc. Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery
JP7569336B2 (ja) 2019-06-11 2024-10-17 サイファイ エス.ピー.エー. マイクロエマルション組成物
JP6622950B1 (ja) * 2019-07-08 2019-12-18 株式会社Moresco マイクロエマルションを調製するための組成物、マイクロエマルション、これらの製造方法、及びマイクロエマルションの利用
JP7785295B2 (ja) * 2020-11-19 2025-12-15 学校法人日本大学 網膜循環障害及び網膜神経血管連関障害の改善用又は予防用点眼剤
US20240408010A1 (en) * 2021-10-01 2024-12-12 University Of South Africa A Nano Emulsified Phyto-Drug For Transdermal Treatment of Diabetes
WO2025034554A1 (en) * 2023-08-04 2025-02-13 Ads Therapeutics Llc Compositions and methods for delivery of ophthalmological actives
IL327899A (en) 2023-10-23 2026-06-01 Inmed Pharmaceuticals Inc Compositions and methods for use of cannabinol compounds in neuroprotection
WO2026085060A1 (en) * 2024-10-15 2026-04-23 Virginia Commonwealth University Ppara agonist loaded microemulsion and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI398261B (zh) * 2003-12-17 2013-06-11 Alcon Inc 血清類澱粉a基因於診斷及治療青光眼及鑑定抗青光眼劑上之用途
US7569612B1 (en) * 2006-08-21 2009-08-04 Mutual Pharmaceutical Company, Inc. Methods of use of fenofibric acid
US20090082470A1 (en) * 2007-09-24 2009-03-26 Rafal Farjo Stat3 inhibiting compositions and methods
US8652443B2 (en) * 2008-02-14 2014-02-18 Precision Dermatology, Inc. Foamable microemulsion compositions for topical administration
AU2012214146A1 (en) * 2011-02-11 2013-08-29 Psivida Us, Inc. Methods of treating macular edema using antiedema therapeutics
WO2013049621A1 (en) * 2011-09-29 2013-04-04 The Board Of Regents Of The University Of Oklahoma Ophthalmic compositions comprising ppar-alpha agonists and methods of production and use thereof

Also Published As

Publication number Publication date
EP2968139B1 (en) 2018-05-23
JP6348567B2 (ja) 2018-06-27
AU2014244154A1 (en) 2015-09-24
WO2014160079A1 (en) 2014-10-02
PT2968139T (pt) 2018-06-18
US9149453B2 (en) 2015-10-06
PL2968139T3 (pl) 2018-10-31
CN105451718A (zh) 2016-03-30
EP2968139A1 (en) 2016-01-20
US8968775B2 (en) 2015-03-03
CA2905023A1 (en) 2014-10-02
AU2014244154B2 (en) 2018-08-09
CN105451718B (zh) 2018-09-28
ES2673009T3 (es) 2018-06-19
DK2968139T3 (en) 2018-06-25
US20150164846A1 (en) 2015-06-18
JP2016512562A (ja) 2016-04-28
CA2905023C (en) 2019-10-15
US20140275263A1 (en) 2014-09-18

Similar Documents

Publication Publication Date Title
DK2968139T3 (en) PLATFORM FOR TOPIC SUBMISSION OF MICROEMULSION
JP2016512562A5 (enExample)
CN112135603B (zh) 包含奈必洛尔的药物组合物
CN111867560B (zh) 包含噻吗洛尔的药物组合物
JPH05186333A (ja) 眼用組成物
US20100174000A1 (en) Carrier in the form of oil-in-water emulsion notably intended for ophthalmic or dermocosmetic use
KR20150100670A (ko) 레고라페닙을 함유하는 국소 안과 제약 조성물
CN117582396A (zh) 局部眼用制剂的用途
KR20150000405A (ko) 난용성 의약품의 수중유적형 에멀젼 조성물 및 이의 제조방법
ES3012007T3 (en) Lipid-based ophthalmic composition for the treatment of dry eye
WO2023055321A1 (en) Anti-inflammatory microemulsion eye formulations derived from nigella sativa oil
KR101151235B1 (ko) 나노에멀젼 형태의 안과용 조성물
US20140302099A1 (en) Ophthalmic Composition Containing Cyclosporine And method For Preparing Same
Acharya Development and Evaluation of Liquid Crystalline Cubogel for Ocular Delivery of Anti-glaucoma Agents
Shah Design of an Ophthalmic Nanostructured Lipid Carrier Containing Amphotericin B and Nonadecanoic Acid for the Management of Fungal Keratitis
ES2834931T3 (es) Proceso de preparación de un colirio de ciclosporina A
Maw Development of cyclodextrin-based pickering nanoemulsion containing amphotericin b for treatment of fungal keratitis
HK40128015A (en) Ophthalmic compositions containing cyclosporine
HK40044057B (en) Pharmaceutical compositions comprising nebivolol
HK40044057A (en) Pharmaceutical compositions comprising nebivolol