DK2968139T3 - PLATFORM FOR TOPIC SUBMISSION OF MICROEMULSION - Google Patents

PLATFORM FOR TOPIC SUBMISSION OF MICROEMULSION Download PDF

Info

Publication number
DK2968139T3
DK2968139T3 DK14720786.4T DK14720786T DK2968139T3 DK 2968139 T3 DK2968139 T3 DK 2968139T3 DK 14720786 T DK14720786 T DK 14720786T DK 2968139 T3 DK2968139 T3 DK 2968139T3
Authority
DK
Denmark
Prior art keywords
oil
api
surfactants
eye
pharmaceutical composition
Prior art date
Application number
DK14720786.4T
Other languages
Danish (da)
English (en)
Inventor
Ronald A Wassel
Rafal A Farjo
Alexander B Quiambao
Fadee George Mondalek
Didier J Nuno
Original Assignee
Eyecro Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eyecro Llc filed Critical Eyecro Llc
Application granted granted Critical
Publication of DK2968139T3 publication Critical patent/DK2968139T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK14720786.4T 2013-03-14 2014-03-13 PLATFORM FOR TOPIC SUBMISSION OF MICROEMULSION DK2968139T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361784005P 2013-03-14 2013-03-14
PCT/US2014/025773 WO2014160079A1 (en) 2013-03-14 2014-03-13 Microemulsion topical delivery platform

Publications (1)

Publication Number Publication Date
DK2968139T3 true DK2968139T3 (en) 2018-06-25

Family

ID=50628949

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14720786.4T DK2968139T3 (en) 2013-03-14 2014-03-13 PLATFORM FOR TOPIC SUBMISSION OF MICROEMULSION

Country Status (12)

Country Link
US (2) US8968775B2 (enExample)
EP (1) EP2968139B1 (enExample)
JP (1) JP6348567B2 (enExample)
CN (1) CN105451718B (enExample)
AU (1) AU2014244154B2 (enExample)
CA (1) CA2905023C (enExample)
DK (1) DK2968139T3 (enExample)
ES (1) ES2673009T3 (enExample)
PL (1) PL2968139T3 (enExample)
PT (1) PT2968139T (enExample)
TR (1) TR201808197T4 (enExample)
WO (1) WO2014160079A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2374812B1 (en) 2006-07-13 2015-04-15 Achillion Pharmaceuticals, Inc. 4-amino-4-oxobutanoyl Peptides as Inhibitors of Viral Replication
ES2584534B1 (es) * 2015-03-27 2017-03-13 Retinset, S.L. Formulación tópica oftálmica de bosentan
EP3405183A4 (en) 2016-01-18 2019-12-11 Arisan Therapeutics Inc. ADAMATE DERIVATIVES FOR TREATING A FILOVIRUS INFECTION
LT3266446T (lt) * 2016-07-07 2019-01-25 Laboratorios Salvat, S.A. Oftalmologinė kompozicija, apimanti ricinos aliejų ir vidutinio grandinės ilgio trigliceridą
WO2019018185A1 (en) 2017-07-15 2019-01-24 Arisan Therapeutics Inc. ENANTIOMERICALLY PURE ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTIONS
IL272601B2 (en) * 2017-08-27 2025-03-01 Rhodes Tech Inc Pharmaceutical compositions for the treatment of ophthalmic conditions
US11583497B2 (en) 2017-11-14 2023-02-21 The Schepens Eye Research Institute, Inc. Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery
JP7569336B2 (ja) 2019-06-11 2024-10-17 サイファイ エス.ピー.エー. マイクロエマルション組成物
WO2021005676A1 (ja) * 2019-07-08 2021-01-14 株式会社Moresco マイクロエマルションを調製するための組成物、マイクロエマルション、これらの製造方法、及びマイクロエマルションの利用
US20240415796A1 (en) * 2020-11-19 2024-12-19 Nihon University Eyedrops for ameliorating or preventing retinal circulation disorder and retinal neurovascular coupling disorder
CN119789854A (zh) * 2023-08-04 2025-04-08 Ads医疗有限责任公司 用于递送眼科活性物的组合物和方法
WO2025090133A1 (en) 2023-10-23 2025-05-01 Inmed Pharmaceuticals Inc. Compositions and methods for use of cannabinol compounds in neuroprotection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI398261B (zh) * 2003-12-17 2013-06-11 Alcon Inc 血清類澱粉a基因於診斷及治療青光眼及鑑定抗青光眼劑上之用途
US7569612B1 (en) * 2006-08-21 2009-08-04 Mutual Pharmaceutical Company, Inc. Methods of use of fenofibric acid
WO2009042677A2 (en) * 2007-09-24 2009-04-02 Farjo Rafal A Stat3 inhibiting compositions and methods
US8652443B2 (en) * 2008-02-14 2014-02-18 Precision Dermatology, Inc. Foamable microemulsion compositions for topical administration
CA2827082A1 (en) * 2011-02-11 2012-08-16 Psivida Us, Inc. Methods of treating macular edema using antiedema therapeutics
WO2013049621A1 (en) * 2011-09-29 2013-04-04 The Board Of Regents Of The University Of Oklahoma Ophthalmic compositions comprising ppar-alpha agonists and methods of production and use thereof

Also Published As

Publication number Publication date
JP2016512562A (ja) 2016-04-28
CN105451718A (zh) 2016-03-30
EP2968139A1 (en) 2016-01-20
TR201808197T4 (tr) 2018-07-23
US8968775B2 (en) 2015-03-03
CN105451718B (zh) 2018-09-28
AU2014244154A1 (en) 2015-09-24
AU2014244154B2 (en) 2018-08-09
PL2968139T3 (pl) 2018-10-31
WO2014160079A1 (en) 2014-10-02
US9149453B2 (en) 2015-10-06
EP2968139B1 (en) 2018-05-23
JP6348567B2 (ja) 2018-06-27
CA2905023C (en) 2019-10-15
ES2673009T3 (es) 2018-06-19
CA2905023A1 (en) 2014-10-02
PT2968139T (pt) 2018-06-18
US20140275263A1 (en) 2014-09-18
US20150164846A1 (en) 2015-06-18

Similar Documents

Publication Publication Date Title
DK2968139T3 (en) PLATFORM FOR TOPIC SUBMISSION OF MICROEMULSION
JP2016512562A5 (enExample)
Tamilvanan et al. The potential of lipid emulsion for ocular delivery of lipophilic drugs
AU2008310956B2 (en) Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors
JP7496778B2 (ja) チモロールを含む医薬組成物
JP6452725B2 (ja) 眼疾患の治療のための膜付着性の自己組織化システム
CN112135603B (zh) 包含奈必洛尔的药物组合物
JPH0899867A (ja) 眼科用ビヒクルとして有用な水中油型ナノエマルジョンおよびその調製法
CN113518619A (zh) 用于治疗眼部新生血管形成的药物组合物
EP3445331A1 (en) Preservative free pharmaceutical ophthalmic compositions
WO2020231670A9 (en) Triamcinolone acetonide-loaded liposomes topical ophthalmic formulations for prevention of macular thickening and its associated visual outcomes after lens surgery
KR20150000405A (ko) 난용성 의약품의 수중유적형 에멀젼 조성물 및 이의 제조방법
ES3012007T3 (en) Lipid-based ophthalmic composition for the treatment of dry eye
Khan et al. Self-Nano Emulsifying Drug delivery system (SNEEDS) for Ocular Administration
Acharya Development and Evaluation of Liquid Crystalline Cubogel for Ocular Delivery of Anti-glaucoma Agents
US20230241080A1 (en) Triamcinolone acetonide-loaded liposomes topical ophthalmic formulations as primary therapy for macular edema secondary to branch retinal vein occlusion
WO2023055321A1 (en) Anti-inflammatory microemulsion eye formulations derived from nigella sativa oil
HK40044057B (zh) 包含奈必洛尔的药物组合物
HK40044057A (en) Pharmaceutical compositions comprising nebivolol
Khodakiya Formulation Design and Optimization of topical Microemulsion in Situ Gelling System: Drug Delivery to Posterior Segment of the Eye