CA2905023C - Microemulsion topical delivery platform - Google Patents
Microemulsion topical delivery platform Download PDFInfo
- Publication number
- CA2905023C CA2905023C CA2905023A CA2905023A CA2905023C CA 2905023 C CA2905023 C CA 2905023C CA 2905023 A CA2905023 A CA 2905023A CA 2905023 A CA2905023 A CA 2905023A CA 2905023 C CA2905023 C CA 2905023C
- Authority
- CA
- Canada
- Prior art keywords
- eye
- oil
- surfactants
- disease
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361784005P | 2013-03-14 | 2013-03-14 | |
| US61/784,005 | 2013-03-14 | ||
| PCT/US2014/025773 WO2014160079A1 (en) | 2013-03-14 | 2014-03-13 | Microemulsion topical delivery platform |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2905023A1 CA2905023A1 (en) | 2014-10-02 |
| CA2905023C true CA2905023C (en) | 2019-10-15 |
Family
ID=50628949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2905023A Active CA2905023C (en) | 2013-03-14 | 2014-03-13 | Microemulsion topical delivery platform |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8968775B2 (enExample) |
| EP (1) | EP2968139B1 (enExample) |
| JP (1) | JP6348567B2 (enExample) |
| CN (1) | CN105451718B (enExample) |
| AU (1) | AU2014244154B2 (enExample) |
| CA (1) | CA2905023C (enExample) |
| DK (1) | DK2968139T3 (enExample) |
| ES (1) | ES2673009T3 (enExample) |
| PL (1) | PL2968139T3 (enExample) |
| PT (1) | PT2968139T (enExample) |
| TR (1) | TR201808197T4 (enExample) |
| WO (1) | WO2014160079A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2374812B1 (en) | 2006-07-13 | 2015-04-15 | Achillion Pharmaceuticals, Inc. | 4-amino-4-oxobutanoyl Peptides as Inhibitors of Viral Replication |
| ES2584534B1 (es) * | 2015-03-27 | 2017-03-13 | Retinset, S.L. | Formulación tópica oftálmica de bosentan |
| EP3405183A4 (en) | 2016-01-18 | 2019-12-11 | Arisan Therapeutics Inc. | ADAMATE DERIVATIVES FOR TREATING A FILOVIRUS INFECTION |
| LT3266446T (lt) * | 2016-07-07 | 2019-01-25 | Laboratorios Salvat, S.A. | Oftalmologinė kompozicija, apimanti ricinos aliejų ir vidutinio grandinės ilgio trigliceridą |
| WO2019018185A1 (en) | 2017-07-15 | 2019-01-24 | Arisan Therapeutics Inc. | ENANTIOMERICALLY PURE ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTIONS |
| IL272601B2 (en) * | 2017-08-27 | 2025-03-01 | Rhodes Tech Inc | Pharmaceutical compositions for the treatment of ophthalmic conditions |
| US11583497B2 (en) | 2017-11-14 | 2023-02-21 | The Schepens Eye Research Institute, Inc. | Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery |
| JP7569336B2 (ja) | 2019-06-11 | 2024-10-17 | サイファイ エス．ピー．エー． | マイクロエマルション組成物 |
| WO2021005676A1 (ja) * | 2019-07-08 | 2021-01-14 | 株式会社Moresco | マイクロエマルションを調製するための組成物、マイクロエマルション、これらの製造方法、及びマイクロエマルションの利用 |
| US20240415796A1 (en) * | 2020-11-19 | 2024-12-19 | Nihon University | Eyedrops for ameliorating or preventing retinal circulation disorder and retinal neurovascular coupling disorder |
| CN119789854A (zh) * | 2023-08-04 | 2025-04-08 | Ads医疗有限责任公司 | 用于递送眼科活性物的组合物和方法 |
| WO2025090133A1 (en) | 2023-10-23 | 2025-05-01 | Inmed Pharmaceuticals Inc. | Compositions and methods for use of cannabinol compounds in neuroprotection |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI398261B (zh) * | 2003-12-17 | 2013-06-11 | Alcon Inc | 血清類澱粉ａ基因於診斷及治療青光眼及鑑定抗青光眼劑上之用途 |
| US7569612B1 (en) * | 2006-08-21 | 2009-08-04 | Mutual Pharmaceutical Company, Inc. | Methods of use of fenofibric acid |
| WO2009042677A2 (en) * | 2007-09-24 | 2009-04-02 | Farjo Rafal A | Stat3 inhibiting compositions and methods |
| US8652443B2 (en) * | 2008-02-14 | 2014-02-18 | Precision Dermatology, Inc. | Foamable microemulsion compositions for topical administration |
| CA2827082A1 (en) * | 2011-02-11 | 2012-08-16 | Psivida Us, Inc. | Methods of treating macular edema using antiedema therapeutics |
| WO2013049621A1 (en) * | 2011-09-29 | 2013-04-04 | The Board Of Regents Of The University Of Oklahoma | Ophthalmic compositions comprising ppar-alpha agonists and methods of production and use thereof |
-
2014
- 2014-03-13 CN CN201480027477.7A patent/CN105451718B/zh active Active
- 2014-03-13 DK DK14720786.4T patent/DK2968139T3/en active
- 2014-03-13 JP JP2016501962A patent/JP6348567B2/ja active Active
- 2014-03-13 EP EP14720786.4A patent/EP2968139B1/en active Active
- 2014-03-13 WO PCT/US2014/025773 patent/WO2014160079A1/en not_active Ceased
- 2014-03-13 PL PL14720786T patent/PL2968139T3/pl unknown
- 2014-03-13 ES ES14720786.4T patent/ES2673009T3/es active Active
- 2014-03-13 PT PT147207864T patent/PT2968139T/pt unknown
- 2014-03-13 CA CA2905023A patent/CA2905023C/en active Active
- 2014-03-13 AU AU2014244154A patent/AU2014244154B2/en active Active
- 2014-03-13 TR TR2018/08197T patent/TR201808197T4/tr unknown
- 2014-03-14 US US14/212,675 patent/US8968775B2/en active Active - Reinstated
-
2015
- 2015-02-24 US US14/630,073 patent/US9149453B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016512562A (ja) | 2016-04-28 |
| CN105451718A (zh) | 2016-03-30 |
| EP2968139A1 (en) | 2016-01-20 |
| TR201808197T4 (tr) | 2018-07-23 |
| US8968775B2 (en) | 2015-03-03 |
| CN105451718B (zh) | 2018-09-28 |
| AU2014244154A1 (en) | 2015-09-24 |
| AU2014244154B2 (en) | 2018-08-09 |
| PL2968139T3 (pl) | 2018-10-31 |
| WO2014160079A1 (en) | 2014-10-02 |
| US9149453B2 (en) | 2015-10-06 |
| EP2968139B1 (en) | 2018-05-23 |
| JP6348567B2 (ja) | 2018-06-27 |
| DK2968139T3 (en) | 2018-06-25 |
| ES2673009T3 (es) | 2018-06-19 |
| CA2905023A1 (en) | 2014-10-02 |
| PT2968139T (pt) | 2018-06-18 |
| US20140275263A1 (en) | 2014-09-18 |
| US20150164846A1 (en) | 2015-06-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2905023C (en) | Microemulsion topical delivery platform | |
| JP2016512562A5 (enExample) | ||
| Tamilvanan et al. | The potential of lipid emulsion for ocular delivery of lipophilic drugs | |
| US11576893B2 (en) | Pharmaceutical compositions comprising nebivolol | |
| JP7496778B2 (ja) | チモロールを含む医薬組成物 | |
| CA2802162A1 (en) | Ophthalmic compositions for the administration of liposoluble acitve ingredients | |
| CA2949954A1 (en) | Topical formulations and uses thereof | |
| JP7669326B2 (ja) | 局所製剤およびその使用 | |
| KR20150000405A (ko) | 난용성 의약품의 수중유적형 에멀젼 조성물 및 이의 제조방법 | |
| ES3012007T3 (en) | Lipid-based ophthalmic composition for the treatment of dry eye | |
| ES2944784B2 (es) | Microemulsión oftálmica, procedimiento de obtención y uso dado a la misma | |
| Khan et al. | Self-Nano Emulsifying Drug delivery system (SNEEDS) for Ocular Administration | |
| US20140302099A1 (en) | Ophthalmic Composition Containing Cyclosporine And method For Preparing Same | |
| Acharya | Development and Evaluation of Liquid Crystalline Cubogel for Ocular Delivery of Anti-glaucoma Agents | |
| CN120732828A (zh) | 一种含有ar-15512的组合物及其制备方法和应用 | |
| HK40044057B (zh) | 包含奈必洛尔的药物组合物 | |
| HK40044057A (en) | Pharmaceutical compositions comprising nebivolol | |
| Baravkar et al. | REVIEW ON A PROMISING STRATEGY FOR ENHANCED OCULAR DRUG DELIVERY SYSTEM | |
| Khodakiya | Formulation Design and Optimization of topical Microemulsion in Situ Gelling System: Drug Delivery to Posterior Segment of the Eye |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20170109 |