TR201802700T4 - Sterol deriveleri ve dönüştürülmüş astrosit hücreleri içeren hastalıkların tedavi edilmesine yönelik veya malignan hemopatilerin tedavi edilmesine yönelik olarak bunların kullanımı. - Google Patents

Sterol deriveleri ve dönüştürülmüş astrosit hücreleri içeren hastalıkların tedavi edilmesine yönelik veya malignan hemopatilerin tedavi edilmesine yönelik olarak bunların kullanımı. Download PDF

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Publication number
TR201802700T4
TR201802700T4 TR2018/02700T TR201802700T TR201802700T4 TR 201802700 T4 TR201802700 T4 TR 201802700T4 TR 2018/02700 T TR2018/02700 T TR 2018/02700T TR 201802700 T TR201802700 T TR 201802700T TR 201802700 T4 TR201802700 T4 TR 201802700T4
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TR
Turkey
Prior art keywords
dimethyl
molecule
cells
cyclopenta
compound
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Application number
TR2018/02700T
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English (en)
Turkish (tr)
Inventor
Clarion Ludovic
Mersel Marcel
Petite Didier
Original Assignee
Beta Innov
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Publication date
Application filed by Beta Innov filed Critical Beta Innov
Publication of TR201802700T4 publication Critical patent/TR201802700T4/tr

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
TR2018/02700T 2012-05-10 2013-05-07 Sterol deriveleri ve dönüştürülmüş astrosit hücreleri içeren hastalıkların tedavi edilmesine yönelik veya malignan hemopatilerin tedavi edilmesine yönelik olarak bunların kullanımı. TR201802700T4 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12305518.8A EP2662382B1 (fr) 2012-05-10 2012-05-10 Dérivés de stérol, leur procédé de préparation, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement du glioblastome multiple
US201261656151P 2012-06-06 2012-06-06

Publications (1)

Publication Number Publication Date
TR201802700T4 true TR201802700T4 (tr) 2018-03-21

Family

ID=46149353

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2018/02700T TR201802700T4 (tr) 2012-05-10 2013-05-07 Sterol deriveleri ve dönüştürülmüş astrosit hücreleri içeren hastalıkların tedavi edilmesine yönelik veya malignan hemopatilerin tedavi edilmesine yönelik olarak bunların kullanımı.

Country Status (24)

Country Link
US (1) US10800806B2 (el)
EP (2) EP2662382B1 (el)
JP (1) JP6270823B2 (el)
KR (1) KR102160316B1 (el)
CN (1) CN104302655B (el)
BR (1) BR112014026948B1 (el)
CA (1) CA2871714C (el)
CY (2) CY1117723T1 (el)
DK (2) DK2662382T3 (el)
ES (2) ES2580331T3 (el)
HK (2) HK1191654A1 (el)
HR (2) HRP20160624T1 (el)
HU (2) HUE029243T2 (el)
IN (1) IN2014DN09437A (el)
LT (1) LT2847204T (el)
ME (1) ME02436B (el)
PL (2) PL2662382T3 (el)
PT (2) PT2662382T (el)
RS (2) RS54926B1 (el)
RU (1) RU2627710C2 (el)
SI (2) SI2662382T1 (el)
SM (1) SMT201600215B (el)
TR (1) TR201802700T4 (el)
WO (1) WO2013168096A1 (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3013048A1 (fr) * 2013-11-12 2015-05-15 Beta Innov Derive de sterol, son procede de preparation, composition pharmaceutique le contenant et son utilisation pour le traitement du glioblastome multiforme
EP3593789A1 (fr) * 2018-07-11 2020-01-15 Beta Innov Composition contenant un dérivé de 7beta-hydroxycholestérol et un véhicule lipidique, et son utilisation dans le traitement de pathologies néoplasiques
KR20220156177A (ko) * 2021-05-18 2022-11-25 연세대학교 산학협력단 암의 예방, 개선 또는 치료용 조성물
KR20220156469A (ko) * 2021-05-18 2022-11-25 연세대학교 산학협력단 암의 예방, 개선 또는 치료용 조성물
WO2024030660A2 (en) * 2022-08-04 2024-02-08 University Of Massachusetts Cholesterol-modified hyaluronic acids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9602100D0 (sv) 1996-05-30 1996-05-30 Magnus Axelson New pharmaceuticals
WO2004029068A1 (en) * 2002-09-25 2004-04-08 Forbes Medi-Tech Inc. Derivatives comprising sterols and/or stanols and specific classes of anti-inflammatory agents and use thereof in treating or preventing cardiovascular disease

Also Published As

Publication number Publication date
RS57065B1 (sr) 2018-06-29
ES2580331T3 (es) 2016-08-23
ES2662123T3 (es) 2018-04-05
RS54926B1 (sr) 2016-10-31
PT2847204T (pt) 2018-03-21
LT2847204T (lt) 2018-03-26
CA2871714C (en) 2022-09-20
PT2662382T (pt) 2016-07-13
ME02436B (me) 2016-09-20
IN2014DN09437A (el) 2015-07-17
CY1117723T1 (el) 2017-05-17
BR112014026948B1 (pt) 2022-05-24
KR102160316B1 (ko) 2020-09-25
EP2662382A1 (fr) 2013-11-13
HRP20180345T1 (hr) 2018-06-01
HK1207385A1 (en) 2016-01-29
US10800806B2 (en) 2020-10-13
HUE029243T2 (en) 2017-02-28
EP2662382B1 (fr) 2016-04-06
HRP20160624T1 (hr) 2016-08-12
CN104302655A (zh) 2015-01-21
SMT201600215B (it) 2016-08-31
US20150086615A1 (en) 2015-03-26
BR112014026948A2 (pt) 2017-06-27
HUE037004T2 (hu) 2018-08-28
SI2847204T1 (en) 2018-05-31
CY1120395T1 (el) 2019-07-10
CA2871714A1 (en) 2013-11-14
KR20150013254A (ko) 2015-02-04
EP2847204B1 (en) 2017-12-13
CN104302655B (zh) 2018-04-03
WO2013168096A1 (en) 2013-11-14
JP2015520146A (ja) 2015-07-16
SI2662382T1 (sl) 2016-08-31
EP2847204A1 (en) 2015-03-18
RU2627710C2 (ru) 2017-08-10
HK1191654A1 (zh) 2014-08-01
RU2014149705A (ru) 2016-07-10
PL2662382T3 (pl) 2016-10-31
DK2847204T3 (en) 2018-03-12
DK2662382T3 (en) 2016-06-27
JP6270823B2 (ja) 2018-01-31
PL2847204T3 (pl) 2018-06-29

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