TR200900437T1 - Kontrollü Salınım Formülasyonları ve Bunlarla İlişkili Yöntemler - Google Patents

Kontrollü Salınım Formülasyonları ve Bunlarla İlişkili Yöntemler

Info

Publication number
TR200900437T1
TR200900437T1 TR2009/00437T TR200900437T TR200900437T1 TR 200900437 T1 TR200900437 T1 TR 200900437T1 TR 2009/00437 T TR2009/00437 T TR 2009/00437T TR 200900437 T TR200900437 T TR 200900437T TR 200900437 T1 TR200900437 T1 TR 200900437T1
Authority
TR
Turkey
Prior art keywords
layer
layers
controlled release
release formulations
related methods
Prior art date
Application number
TR2009/00437T
Other languages
English (en)
Inventor
Melaku Teshome
Parikh Nilesh H.
Original Assignee
Watson Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Watson Laboratories, Inc. filed Critical Watson Laboratories, Inc.
Publication of TR200900437T1 publication Critical patent/TR200900437T1/tr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

İçerisinde yer alan etken maddelerin salınım özelliklerini etkileyen geometrik bir konfıgürasyona sahip farmasötik bir formülasyon ve bununla ilişkili yöntemler temin edilmektedir. Buluşun bir yönüne göre, yavaş salınımlı bir oral dozaj farmasötik tableti (10) birinci bir etken maddeyi içeren birinci bir tabakaya (12) yer verebilmekte ve burada birinci tabaka (12) komşu iki kontrollü salınım tabakasının (14) arasına yerleştirilmekte ve komşu tabakalardan (14) en az biri, en az bir tane ikinci etken maddeyi barındırmaktadır, iki komşu tabaka (14), birinci tabakanın (12) bir parçasını örtecek biçimde düzenlenmektedir. Oral dozaj biçiminin genel konfigürasyonuna ve geometrik tasarımına bağlı olarak, iki komşu tabaka (14) birbirinden ayrı tabakalar halinde olabilmekte veya tek bir sürekli tabaka halinde birleştirilebilmektedir.
TR2009/00437T 2006-07-19 2007-07-19 Kontrollü Salınım Formülasyonları ve Bunlarla İlişkili Yöntemler TR200900437T1 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/458,651 US8765178B2 (en) 2006-07-19 2006-07-19 Controlled release formulations and associated methods

Publications (1)

Publication Number Publication Date
TR200900437T1 true TR200900437T1 (tr) 2009-05-21

Family

ID=38957414

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2009/00437T TR200900437T1 (tr) 2006-07-19 2007-07-19 Kontrollü Salınım Formülasyonları ve Bunlarla İlişkili Yöntemler

Country Status (13)

Country Link
US (1) US8765178B2 (tr)
EP (1) EP2043647A4 (tr)
JP (1) JP5202522B2 (tr)
CN (2) CN101553230B (tr)
AU (1) AU2007275557A1 (tr)
BR (1) BRPI0714304A2 (tr)
CA (1) CA2657913C (tr)
CO (1) CO6150130A2 (tr)
MX (1) MX2009000730A (tr)
NZ (2) NZ590674A (tr)
RU (1) RU2463049C2 (tr)
TR (1) TR200900437T1 (tr)
WO (1) WO2008011169A2 (tr)

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CA2657913C (en) 2015-09-22
CA2657913A1 (en) 2008-01-24
JP5202522B2 (ja) 2013-06-05
CO6150130A2 (es) 2010-04-20
RU2463049C2 (ru) 2012-10-10
JP2009543875A (ja) 2009-12-10
MX2009000730A (es) 2009-03-20
WO2008011169A3 (en) 2008-11-06
US8765178B2 (en) 2014-07-01
CN101553230A (zh) 2009-10-07
AU2007275557A1 (en) 2008-01-24
US20080020039A1 (en) 2008-01-24
EP2043647A2 (en) 2009-04-08
CN101553230B (zh) 2012-04-11
RU2009105373A (ru) 2010-08-27
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WO2008011169A2 (en) 2008-01-24

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