CY1115652T1 - Μορφη δοσολογιας που περιεχει δυο δραστικα φαρμακευτικα συστατικα μειγματος σε διαφορετικες φυσικες μορφες - Google Patents
Μορφη δοσολογιας που περιεχει δυο δραστικα φαρμακευτικα συστατικα μειγματος σε διαφορετικες φυσικες μορφεςInfo
- Publication number
- CY1115652T1 CY1115652T1 CY20141100879T CY141100879T CY1115652T1 CY 1115652 T1 CY1115652 T1 CY 1115652T1 CY 20141100879 T CY20141100879 T CY 20141100879T CY 141100879 T CY141100879 T CY 141100879T CY 1115652 T1 CY1115652 T1 CY 1115652T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pellet
- dosage form
- different natural
- mixing ingredients
- natural forms
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
Abstract
Μορφή δοσολογίας για χορήγηση δύο ή περισσότερων φαρμακευτικών συστατικών μείγματος για ένα υποκείμενο, που περιλαμβάνει πρώτη φαρμακευτική σύνθεση που περιλαμβάνει πρώτο δραστικό φαρμακευτικό συστατικό μείγματος και προαιρετικώς ένα ή περισσότερα φαρμακευτικώς αποδεκτά έκδοχα σε πρώτη φυσική μορφή που επιλέγεται από την ομάδα συνιστάμενη από μορφή κόνεος, κοκκίου, σβώλου, σφαιριδίου, ή μινι-δισκίου και τουλάχιστον μια δεύτερη φαρμακευτική σύνθεση που περιλαμβάνει δεύτερο δραστικό φαρμακευτικό συστατικό μείγματος και προαιρετικώς ένα ή περισσότερο φαρμακευτικώς αποδεκτά έκδοχα σε δεύτερη φυσική μορφή που επιλέγεται από την ομάδα συνιστάμενη από μορφή κοκκίου, σβώλου, σφαιριδίου, μινι-δισκίου, ή δισκίου όπου η σύνθεση χαρακτηρίζεται από το γεγονός ότι οι εν λόγω πρώτες και δεύτερες φυσικές μορφές επιλέγονται να είναι διαφορετικές για να ελαχιστοποιηθούν οι αλληλεπιδράσεις μεταξύ των εν λόγω πρώτων και δεύτερων φαρμακευτικών συνθέσεων και για να επιτραπεί ο διαχωρισμός των εν λόγω πρώτων και δεύτερων φαρμακευτικών συνθέσεων για ανάλυση βάσει της διαφοράς μεγέθους.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2007900682A AU2007900682A0 (en) | 2007-02-09 | Novel Formulation | |
EP20080706056 EP2120878B1 (en) | 2007-02-09 | 2008-02-11 | A dosage form containing two active pharmaceutical ingredients in different physical forms |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1115652T1 true CY1115652T1 (el) | 2017-01-25 |
Family
ID=39681201
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20141100879T CY1115652T1 (el) | 2007-02-09 | 2014-10-27 | Μορφη δοσολογιας που περιεχει δυο δραστικα φαρμακευτικα συστατικα μειγματος σε διαφορετικες φυσικες μορφες |
Country Status (15)
Country | Link |
---|---|
US (1) | US9095519B2 (el) |
EP (1) | EP2120878B1 (el) |
JP (1) | JP5467870B2 (el) |
CN (1) | CN101674811B (el) |
AU (1) | AU2008213744B2 (el) |
CA (1) | CA2677623C (el) |
CY (1) | CY1115652T1 (el) |
DK (1) | DK2120878T3 (el) |
ES (1) | ES2522297T3 (el) |
HR (1) | HRP20141008T1 (el) |
NZ (1) | NZ599031A (el) |
PL (1) | PL2120878T3 (el) |
PT (1) | PT2120878E (el) |
SI (1) | SI2120878T1 (el) |
WO (1) | WO2008095263A1 (el) |
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US20100189797A1 (en) * | 2002-06-10 | 2010-07-29 | Julien Mendlewicz | Oral antidepressant formulation |
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US11241420B2 (en) | 2007-04-11 | 2022-02-08 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
EP2184055A1 (en) * | 2008-11-07 | 2010-05-12 | LEK Pharmaceuticals d.d. | Process for preparing solid dosage forms of rosiglitazone maleate |
CN101780078B (zh) * | 2010-02-10 | 2012-02-29 | 威特(湖南)药业有限公司 | 替米沙坦和氨氯地平复方制剂及其制备方法 |
EP2368543A1 (en) | 2010-03-25 | 2011-09-28 | KRKA, tovarna zdravil, d.d., Novo mesto | Method of preparing a granulated pharmaceutical composition comprising simvastatin and/or ezetimibe |
ES2581158T3 (es) * | 2010-05-06 | 2016-09-01 | Cal International Limited | Una composición farmacéutica que comprende aspirina y bisoprolol |
CN102247366B (zh) * | 2010-05-18 | 2015-04-15 | 广州白云山制药股份有限公司广州白云山制药总厂 | 包括依那普利和非洛地平的药物组合物缓释制剂 |
CN102028670A (zh) * | 2010-09-06 | 2011-04-27 | 邓俐丽 | 一种包含替米沙坦和钙离子通道拮抗剂的复方胶囊剂 |
KR20120068277A (ko) * | 2010-12-17 | 2012-06-27 | 한미사이언스 주식회사 | HMG-CoA 환원효소 억제제 및 아스피린을 포함하는 약제학적 복합제제 |
IN2014DN03169A (el) | 2011-10-21 | 2015-05-22 | Takeda Pharmaceutical | |
EP2793866B2 (en) | 2011-12-21 | 2023-10-25 | Elanco Tiergesundheit AG | Bilayer tablet comprising benazepril hydrochloride and pimobendan |
CN103169704A (zh) * | 2011-12-26 | 2013-06-26 | 上海复星医药产业发展有限公司 | 烟酸和辛伐他汀复方缓释胶囊制剂及其制备方法 |
EP3501501A1 (en) | 2012-02-17 | 2019-06-26 | Egis Gyógyszergyár Zrt. | Pharmaceutical formulation having improved stability |
ES2924478T3 (es) | 2012-03-15 | 2022-10-07 | Boehringer Ingelheim Vetmedica Gmbh | Formulación de comprimidos farmacéuticos para el sector médico veterinario, método de producción y uso de los mismos |
CN102670630B (zh) * | 2012-05-23 | 2013-11-27 | 重庆康刻尔制药有限公司 | 一种缬沙坦与氢氯噻嗪药物组合物胶囊剂及其制备方法 |
IN2015DN01093A (el) * | 2012-08-28 | 2015-06-26 | Dsm Sinochem Pharm Nl Bv | |
EP2810644A1 (en) * | 2013-06-06 | 2014-12-10 | Ferrer Internacional, S.A. | Oral formulation for the treatment of cardiovascular diseases |
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CN103462903B (zh) * | 2013-08-26 | 2016-06-22 | 中国人民解放军第150中心医院 | 一种盐酸吡格列酮缓释微丸制剂的制备工艺 |
WO2015038854A1 (en) * | 2013-09-13 | 2015-03-19 | R.P. Scherer Technologies, Llc | Encased-pellet tablets |
HU231036B1 (hu) * | 2013-09-30 | 2019-12-30 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Koleszterin bioszintézis gátló hatóanyagot és koleszterin abszorpciót gátló hatóanyagot tartalmazó kombinációs gyógyszerkészítmény |
WO2015073573A1 (en) * | 2013-11-14 | 2015-05-21 | Jacobs Michael M | Compositions and methods for the prevention and treatment of alcohol-induced hangover syndrome |
KR101910901B1 (ko) * | 2013-11-29 | 2018-10-24 | 한미약품 주식회사 | 암로디핀, 로자탄 및 로수바스타틴을 포함하는 약제학적 복합 제제 |
CN104382896A (zh) * | 2014-11-04 | 2015-03-04 | 万全万特制药江苏有限公司 | 含有依折麦布和辛伐他汀的药物组合物 |
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-
2008
- 2008-02-11 PT PT08706056T patent/PT2120878E/pt unknown
- 2008-02-11 US US12/526,326 patent/US9095519B2/en active Active
- 2008-02-11 CN CN200880004561.1A patent/CN101674811B/zh not_active Expired - Fee Related
- 2008-02-11 WO PCT/AU2008/000169 patent/WO2008095263A1/en active Application Filing
- 2008-02-11 CA CA2677623A patent/CA2677623C/en not_active Expired - Fee Related
- 2008-02-11 JP JP2009548549A patent/JP5467870B2/ja not_active Expired - Fee Related
- 2008-02-11 ES ES08706056.2T patent/ES2522297T3/es active Active
- 2008-02-11 PL PL08706056T patent/PL2120878T3/pl unknown
- 2008-02-11 SI SI200831315T patent/SI2120878T1/sl unknown
- 2008-02-11 NZ NZ59903108A patent/NZ599031A/xx not_active IP Right Cessation
- 2008-02-11 DK DK08706056T patent/DK2120878T3/da active
- 2008-02-11 AU AU2008213744A patent/AU2008213744B2/en not_active Ceased
- 2008-02-11 EP EP20080706056 patent/EP2120878B1/en active Active
-
2014
- 2014-10-21 HR HRP20141008AT patent/HRP20141008T1/hr unknown
- 2014-10-27 CY CY20141100879T patent/CY1115652T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
US20100092549A1 (en) | 2010-04-15 |
CN101674811A (zh) | 2010-03-17 |
HRP20141008T1 (hr) | 2015-01-02 |
CN101674811B (zh) | 2015-08-19 |
SI2120878T1 (sl) | 2014-12-31 |
PL2120878T3 (pl) | 2015-01-30 |
WO2008095263A1 (en) | 2008-08-14 |
JP5467870B2 (ja) | 2014-04-09 |
DK2120878T3 (da) | 2014-11-03 |
AU2008213744B2 (en) | 2013-12-05 |
ES2522297T3 (es) | 2014-11-14 |
NZ599031A (en) | 2013-11-29 |
JP2010518028A (ja) | 2010-05-27 |
EP2120878A4 (en) | 2013-05-08 |
CA2677623C (en) | 2015-04-07 |
PT2120878E (pt) | 2014-11-05 |
AU2008213744A1 (en) | 2008-08-14 |
CA2677623A1 (en) | 2008-08-14 |
EP2120878B1 (en) | 2014-07-30 |
EP2120878A1 (en) | 2009-11-25 |
US9095519B2 (en) | 2015-08-04 |
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