TR200301277T3 - Laboratuar ortamında kopyalama/dönüştürme sistemi kullanarak peptidler üretmek için işlem. EP1319074 - Google Patents

Laboratuar ortamında kopyalama/dönüştürme sistemi kullanarak peptidler üretmek için işlem. EP1319074

Info

Publication number
TR200301277T3
TR200301277T3 TR2003/01277T TR200301277T TR200301277T3 TR 200301277 T3 TR200301277 T3 TR 200301277T3 TR 2003/01277 T TR2003/01277 T TR 2003/01277T TR 200301277 T TR200301277 T TR 200301277T TR 200301277 T3 TR200301277 T3 TR 200301277T3
Authority
TR
Turkey
Prior art keywords
reaction system
peptide
rna
transcription
transformation system
Prior art date
Application number
TR2003/01277T
Other languages
English (en)
Inventor
Inoue Akio
Shimizu Yoshihiro
Ueda Takuya
Original Assignee
Post Genome Institute Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Post Genome Institute Co., Ltd. filed Critical Post Genome Institute Co., Ltd.
Publication of TR200301277T3 publication Critical patent/TR200301277T3/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Laboratuar ortaminda bir peptid sentez sisteminde üretilen bir peptidin tepkime sisteminden yüksek saflik seviyesinde etkili bir sekilde izole edilebildigi ve ayni zamanda tepkime sistemindeki enerji tüketimi probleminin çözüldügü bir tepkime sisteminin olusturulmasi amaçlanmaktadir. Laboratuar ortaminda bir DNA'nin bir RNA'ya kopyalanma ve daha sonra üretilen RNA'yi dönüstürme tepkime sistemi veya bir RNA'yi dönüstürme tepkime sistemi kullanarak bir peptid veya bir peptid türevi üretmek için bir islem olup, özelligi kopyalama/dönüstürme tepkime sistemini olustutran protein bilesenlerinin bir bölümünün veya tümünün birbirine yapisan bir çift maddenin bir tanesi ile isaretlenmesi ve çiftin diger maddesinin dönüsümden sonra bahsedilen isaretlenmis protein bilesenlerinin yakalanmasi için bir tutucu olarak kullanilmasidir.
TR2003/01277T 2000-12-28 2001-12-06 Laboratuar ortamında kopyalama/dönüştürme sistemi kullanarak peptidler üretmek için işlem. EP1319074 TR200301277T3 (tr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000401417 2000-12-28
JP2001006910 2001-01-15
JP2001227094 2001-07-27
JP2001294795A JP4061043B2 (ja) 2000-12-28 2001-09-26 invitro転写/翻訳系によるペプチド等の製造方法

Publications (1)

Publication Number Publication Date
TR200301277T3 true TR200301277T3 (tr) 2003-11-21

Family

ID=27481947

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2003/01277T TR200301277T3 (tr) 2000-12-28 2001-12-06 Laboratuar ortamında kopyalama/dönüştürme sistemi kullanarak peptidler üretmek için işlem. EP1319074

Country Status (17)

Country Link
US (1) US7118883B2 (tr)
EP (1) EP1319074B1 (tr)
JP (1) JP4061043B2 (tr)
KR (1) KR20030001371A (tr)
AT (1) ATE296885T1 (tr)
AU (1) AU2002221071A1 (tr)
CA (1) CA2400735C (tr)
DE (2) DE60111247T2 (tr)
ES (1) ES2193896T3 (tr)
HU (1) HUP0301723A2 (tr)
IL (1) IL150892A0 (tr)
IS (1) IS6607A (tr)
MX (1) MXPA02008485A (tr)
NO (1) NO20024082L (tr)
PL (1) PL366364A1 (tr)
TR (1) TR200301277T3 (tr)
WO (1) WO2002053582A2 (tr)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2435812C (en) * 2001-01-25 2012-03-27 Anthony C. Forster Process and compositions for peptide, protein and peptidomimetic synthesis
DE10137792A1 (de) * 2001-08-06 2003-02-27 Erdmann Volker Verfahren zur Genexpression
JP4389870B2 (ja) * 2003-06-10 2009-12-24 株式会社島津製作所 哺乳動物培養細胞抽出液を用いた無細胞系タンパク質合成方法
US20040265921A1 (en) * 2003-06-30 2004-12-30 National University Of Singapore Intein-mediated attachment of ligands to proteins for immobilization onto a support
DE10336705A1 (de) * 2003-08-06 2005-03-10 Rina Netzwerk Rna Technologien Verfahren zur Herstellung eines Lysats zur zellfreien Proteinbiosynthese
US7459290B1 (en) 2004-03-30 2008-12-02 Iowa State University Research Foundation, Inc. Methods of using functional 30S subunits
US8603775B2 (en) 2004-04-30 2013-12-10 Biocomber Co., Ltd. Method of disulfide crosslink forming in vitro protein synthesis
WO2008005529A2 (en) 2006-07-07 2008-01-10 The Trustees Columbia University In The City Of New York Cell-mediated directed evolution
JP4931135B2 (ja) * 2007-05-02 2012-05-16 国立大学法人 東京大学 リボソームディスプレイ
US7803623B2 (en) * 2007-10-30 2010-09-28 E.I. Du Pont De Nemours And Company Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate
US9085798B2 (en) 2009-04-30 2015-07-21 Prognosys Biosciences, Inc. Nucleic acid constructs and methods of use
PL2556171T3 (pl) 2010-04-05 2016-04-29 Prognosys Biosciences Inc Oznaczenia biologiczne kodowane przestrzennie
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US9753040B2 (en) 2010-12-01 2017-09-05 Mitsubishi Tanabe Pharma Corporation Polynucleotide construct capable of displaying fab in a cell-free translation system, and method for manufacturing and screening fab using same
JP5948673B2 (ja) 2011-03-10 2016-07-06 ジーンフロンティア株式会社 リポ多糖混入量を低減した蛋白質合成用組成物、該組成物を用いた蛋白質製造方法
US20120258871A1 (en) 2011-04-08 2012-10-11 Prognosys Biosciences, Inc. Peptide constructs and assay systems
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
WO2013067523A1 (en) * 2011-11-04 2013-05-10 Cornell University A prokaryote-based cell-free system for the synthesis of glycoproteins
TWI640541B (zh) 2011-12-28 2018-11-11 中外製藥股份有限公司 Peptide compound having an annular portion and pharmaceutical composition thereof
EP4219706A1 (en) 2012-08-16 2023-08-02 Synthetic Genomics, Inc. Automated dsdna synthesis using a digital to biological converter
JP6159808B2 (ja) * 2012-11-30 2017-07-05 バイオニア コーポレーション 全自動無細胞タンパク質製造装備及びこれを利用したタンパク質の製造方法
US9528137B2 (en) 2013-03-15 2016-12-27 Northwestern University Methods for cell-free protein synthesis
CN105358984B (zh) 2013-03-15 2020-02-18 普罗格诺西斯生物科学公司 用于检测肽/mhc/tcr结合的方法
CN118240918A (zh) 2013-06-25 2024-06-25 普罗格诺西斯生物科学公司 采用微流控装置的空间编码生物分析
WO2015070037A2 (en) 2013-11-08 2015-05-14 Prognosys Biosciences, Inc. Polynucleotide conjugates and methods for analyte detection
EP4119677B1 (en) 2015-04-10 2023-06-28 Spatial Transcriptomics AB Spatially distinguished, multiplex nucleic acid analysis of biological specimens
WO2019035916A1 (en) 2017-08-15 2019-02-21 Northwestern University DESIGN OF PROTEIN GLYCOSYLATION SITES BY RAPID EXPRESSION AND CHARACTERIZATION OF N-GLYCOSYLTRANSFERASES
US11530432B2 (en) 2018-03-19 2022-12-20 Northwestern University Compositions and methods for rapid in vitro synthesis of bioconjugate vaccines in vitro via production and N-glycosylation of protein carriers in detoxified prokaryotic cell lysates
US11725224B2 (en) 2018-04-16 2023-08-15 Northwestern University Methods for co-activating in vitro non-standard amino acid (nsAA) incorporation and glycosylation in crude cell lysates
WO2020040840A2 (en) 2018-06-01 2020-02-27 Northwestern University Expanding the chemical substrates for genetic code reprogramming
US11519033B2 (en) 2018-08-28 2022-12-06 10X Genomics, Inc. Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
US11649485B2 (en) 2019-01-06 2023-05-16 10X Genomics, Inc. Generating capture probes for spatial analysis
US11926867B2 (en) 2019-01-06 2024-03-12 10X Genomics, Inc. Generating capture probes for spatial analysis
EP3976820A1 (en) 2019-05-30 2022-04-06 10X Genomics, Inc. Methods of detecting spatial heterogeneity of a biological sample
WO2021030271A2 (en) 2019-08-09 2021-02-18 Nutcracker Therapeutics, Inc. Methods and apparatuses for manufacturing for removing material from a therapeutic composition
EP4025711A2 (en) 2019-11-08 2022-07-13 10X Genomics, Inc. Enhancing specificity of analyte binding
WO2021091611A1 (en) 2019-11-08 2021-05-14 10X Genomics, Inc. Spatially-tagged analyte capture agents for analyte multiplexing
ES2946357T3 (es) 2019-12-23 2023-07-17 10X Genomics Inc Métodos para el análisis espacial usando ligación con molde de ARN
US11732299B2 (en) 2020-01-21 2023-08-22 10X Genomics, Inc. Spatial assays with perturbed cells
US11702693B2 (en) 2020-01-21 2023-07-18 10X Genomics, Inc. Methods for printing cells and generating arrays of barcoded cells
US11821035B1 (en) 2020-01-29 2023-11-21 10X Genomics, Inc. Compositions and methods of making gene expression libraries
US11898205B2 (en) 2020-02-03 2024-02-13 10X Genomics, Inc. Increasing capture efficiency of spatial assays
US11732300B2 (en) 2020-02-05 2023-08-22 10X Genomics, Inc. Increasing efficiency of spatial analysis in a biological sample
US11835462B2 (en) 2020-02-11 2023-12-05 10X Genomics, Inc. Methods and compositions for partitioning a biological sample
US11891654B2 (en) 2020-02-24 2024-02-06 10X Genomics, Inc. Methods of making gene expression libraries
US11926863B1 (en) 2020-02-27 2024-03-12 10X Genomics, Inc. Solid state single cell method for analyzing fixed biological cells
US11768175B1 (en) 2020-03-04 2023-09-26 10X Genomics, Inc. Electrophoretic methods for spatial analysis
ES2965354T3 (es) 2020-04-22 2024-04-12 10X Genomics Inc Métodos para análisis espacial que usan eliminación de ARN elegido como diana
WO2021237087A1 (en) 2020-05-22 2021-11-25 10X Genomics, Inc. Spatial analysis to detect sequence variants
EP4153775A1 (en) 2020-05-22 2023-03-29 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
WO2021242834A1 (en) 2020-05-26 2021-12-02 10X Genomics, Inc. Method for resetting an array
WO2021247543A2 (en) 2020-06-02 2021-12-09 10X Genomics, Inc. Nucleic acid library methods
WO2021247568A1 (en) 2020-06-02 2021-12-09 10X Genomics, Inc. Spatial trancriptomics for antigen-receptors
WO2021252499A1 (en) 2020-06-08 2021-12-16 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
WO2021252591A1 (en) 2020-06-10 2021-12-16 10X Genomics, Inc. Methods for determining a location of an analyte in a biological sample
WO2021263111A1 (en) 2020-06-25 2021-12-30 10X Genomics, Inc. Spatial analysis of dna methylation
US11761038B1 (en) 2020-07-06 2023-09-19 10X Genomics, Inc. Methods for identifying a location of an RNA in a biological sample
US11981960B1 (en) 2020-07-06 2024-05-14 10X Genomics, Inc. Spatial analysis utilizing degradable hydrogels
US11981958B1 (en) 2020-08-20 2024-05-14 10X Genomics, Inc. Methods for spatial analysis using DNA capture
US11926822B1 (en) 2020-09-23 2024-03-12 10X Genomics, Inc. Three-dimensional spatial analysis
US11827935B1 (en) 2020-11-19 2023-11-28 10X Genomics, Inc. Methods for spatial analysis using rolling circle amplification and detection probes
WO2022140028A1 (en) 2020-12-21 2022-06-30 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
EP4301870A1 (en) 2021-03-18 2024-01-10 10X Genomics, Inc. Multiplex capture of gene and protein expression from a biological sample
EP4196605A1 (en) 2021-09-01 2023-06-21 10X Genomics, Inc. Methods, compositions, and kits for blocking a capture probe on a spatial array

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US264147A (en) * 1882-09-12 Attachment fob sewing machines
DE3379506D1 (en) 1983-08-22 1989-05-03 Kyowa Hakko Kogyo Kk Process for producing peptide
US4710464A (en) 1984-09-27 1987-12-01 Eli Lilly And Company Transcription terminators
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DE3587814T2 (de) 1985-03-30 1994-11-10 Marc Ballivet Verfahren zum erhalten von dns, rns, peptiden, polypeptiden oder proteinen durch dns-rekombinant-verfahren.
CA1340522C (en) * 1987-03-10 1999-05-04 Heinz Dobeli Fusion proteins containing neighbouring histidines for improved purification
SU1618761A1 (ru) 1987-04-29 1991-01-07 Институт Белка Ан Ссср Способ получени пептидов и белков в бесклеточной системе трансл ции
AU649217B2 (en) 1988-11-18 1994-05-19 Regents Of The University Of California, The Method for site-specifically incorporating unnatural amino acids into proteins
US5478730A (en) 1988-12-21 1995-12-26 Institute Of Protein Research Method of preparing polypeptides in cell-free translation system
ES2118066T3 (es) 1989-10-05 1998-09-16 Optein Inc Sintesis y aislamiento, exentos de celulas, de nuevos genes y polipeptidos.
JPH04200390A (ja) 1990-11-30 1992-07-21 Shigeyuki Yokoyama 無細胞ポリペプチド合成系によるポリペプチドの製造方法
US5492817A (en) * 1993-11-09 1996-02-20 Promega Corporation Coupled transcription and translation in eukaryotic cell-free extract
SE9604108D0 (sv) 1996-11-08 1996-11-08 Maans Ehrenberg A method for the labelling of polypeptides and novel labelled polypeptides
US6306628B1 (en) * 1999-08-25 2001-10-23 Ambergen, Incorporated Methods for the detection, analysis and isolation of Nascent proteins
CA2435812C (en) 2001-01-25 2012-03-27 Anthony C. Forster Process and compositions for peptide, protein and peptidomimetic synthesis

Also Published As

Publication number Publication date
NO20024082D0 (no) 2002-08-27
CA2400735C (en) 2008-03-18
HUP0301723A2 (hu) 2003-08-28
ATE296885T1 (de) 2005-06-15
KR20030001371A (ko) 2003-01-06
ES2193896T3 (es) 2005-10-16
US7118883B2 (en) 2006-10-10
DE60111247D1 (de) 2005-07-07
AU2002221071A1 (en) 2002-07-16
WO2002053582A3 (en) 2003-03-20
EP1319074B1 (en) 2005-06-01
JP2003102495A (ja) 2003-04-08
CA2400735A1 (en) 2002-07-11
NO20024082L (no) 2002-08-27
JP4061043B2 (ja) 2008-03-12
ES2193896T1 (es) 2003-11-16
EP1319074A2 (en) 2003-06-18
WO2002053582A2 (en) 2002-07-11
DE1319074T1 (de) 2003-11-27
IS6607A (is) 2002-10-31
PL366364A1 (en) 2005-01-24
IL150892A0 (en) 2003-02-12
US20020123101A1 (en) 2002-09-05
MXPA02008485A (es) 2004-05-17
DE60111247T2 (de) 2006-05-04

Similar Documents

Publication Publication Date Title
TR200301277T3 (tr) Laboratuar ortamında kopyalama/dönüştürme sistemi kullanarak peptidler üretmek için işlem. EP1319074
DE60120713D1 (de) Funktionelles protein array
DE60109443D1 (de) Antigene zusammensetzung die ein polykationisches peptid und inosin und cytosin enthält
CY1106369T1 (el) Μεθοδος ταχειας τυποποιησης μικροοργανισμων με ηλεκτροφορηση πηκτης παλλομενου πεδιου με την οποια τα δειγματα παρασκευαζονται σε ενα εγκλειομενο σε αυτοκλειστο και ευκαμπτο καλουπι
HUP0203567A2 (hu) APRIL-receptor (BCMA) és alkalmazásai
DE3686304D1 (de) Typenspezifische papillomavirus-dns-sequenzen und peptide.
CA2020958A1 (en) Nucleic acid sequence amplification methods
AR031912A2 (es) Subtilasa modificada, acido nucleico, vector, celula microbiana y metodo para producirla
DK0850310T3 (da) Cirkulært DNA molekyle med betinget replikationsorigin, proces til fremstilling deraf og anvendelse deraf i genterapi
ATE553191T1 (de) Codon-optimierte alkalisch phosphatase und ihre expression in hefe
WO2008081938A1 (ja) 耐熱性ビオチン結合性タンパク質の利用法、および当該タンパク質が結合した固体担体
ATE85620T1 (de) Verfahren zur 9-alpha-dehalogenierung von 9-alpha-steroiden.
NO20023276D0 (no) Fremgangsmåte til å fremstille betulinsyre
AU2174002A (en) Method for analyzing proteins
SE0002835D0 (sv) Method and kit for production of monoclonal antibodies
MY128619A (en) Detection of human hepatitis b virus surface antigen mutants by specific amplification and its application on gene chip
WO2001083822A3 (en) Use of representations of dna for genetic analysis
DE602005003922D1 (de) Synthese von spongosin
DE60113660D1 (de) G-protein gekoppelter rezeptor
WO2000075352A3 (en) Hcv/bvdv chimeric genomes and uses thereof
DK1594991T3 (da) Fremgangsmåde til fremstilling af DNA-molekyler
WO2004096999A3 (en) In vitro translation system
PE20001367A1 (es) Sintesis recombinante de beta-lipotropina y otros peptidos
Park et al. Biotechnology; Development of new premix-type DNA Ligases: advantages of premix-type DNA Ligase over solution-type DNA Ligase
ECSP993253A (es) Composiciones de flint y usos de estas (caso x-12671)