TR200202374T2 - Donepezil hidroklorid polimorfları ve üretim prosesleri - Google Patents

Donepezil hidroklorid polimorfları ve üretim prosesleri

Info

Publication number
TR200202374T2
TR200202374T2 TR2002/02374T TR200202374T TR200202374T2 TR 200202374 T2 TR200202374 T2 TR 200202374T2 TR 2002/02374 T TR2002/02374 T TR 2002/02374T TR 200202374 T TR200202374 T TR 200202374T TR 200202374 T2 TR200202374 T2 TR 200202374T2
Authority
TR
Turkey
Prior art keywords
donepezil hydrochloride
production processes
polymorphs
hydrochloride polymorphs
peaks
Prior art date
Application number
TR2002/02374T
Other languages
English (en)
Turkish (tr)
Inventor
Ima Akio
Watanabe Hideaki
Takashi Kajima
Ishihama Yasushi
Ohtsuka Akiyo
Tanaka Tomohide
Narabu Yukio
Original Assignee
Eisai Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1996/003881 external-priority patent/WO1997046526A1/en
Application filed by Eisai Co., Ltd filed Critical Eisai Co., Ltd
Publication of TR200202374T2 publication Critical patent/TR200202374T2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TR2002/02374T 1996-06-07 1997-06-06 Donepezil hidroklorid polimorfları ve üretim prosesleri TR200202374T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP14629396 1996-06-07
PCT/JP1996/003881 WO1997046526A1 (en) 1996-06-07 1996-12-27 Stable polymorphs of donepezil (1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) hydrochloride and process for production
US08/774,802 US6140321A (en) 1996-06-07 1996-12-30 Polymorphs of donepezil hydrochloride and process for production

Publications (1)

Publication Number Publication Date
TR200202374T2 true TR200202374T2 (tr) 2003-01-21

Family

ID=26477192

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2002/02374T TR200202374T2 (tr) 1996-06-07 1997-06-06 Donepezil hidroklorid polimorfları ve üretim prosesleri
TR1998/02531T TR199802531T2 (xx) 1996-06-07 1997-06-06 Donepezil hidroklorid polimorflar� ve �retim prosesleri.

Family Applications After (1)

Application Number Title Priority Date Filing Date
TR1998/02531T TR199802531T2 (xx) 1996-06-07 1997-06-06 Donepezil hidroklorid polimorflar� ve �retim prosesleri.

Country Status (10)

Country Link
CN (1) CN1207282C (de)
AT (1) ATE230396T1 (de)
CY (1) CY2316B1 (de)
CZ (1) CZ296619B6 (de)
DE (1) DE69718216T2 (de)
NO (1) NO20060377L (de)
PL (1) PL330362A1 (de)
PT (1) PT1019374E (de)
TR (2) TR200202374T2 (de)
TW (1) TWI243816B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101906066B (zh) * 2010-08-08 2015-03-11 浙江华海药业股份有限公司 一种制备盐酸奈哌齐晶型i的方法
CN102060752B (zh) * 2011-01-24 2013-03-13 上海右手医药科技开发有限公司 高纯度盐酸多奈哌齐无水i晶型的生产方法及其产品
CN103012247B (zh) * 2013-01-18 2014-12-10 浙江东亚药业有限公司 一种盐酸多奈哌齐无水i晶型的制备方法
CN103694164B (zh) * 2014-01-23 2015-08-12 天津大学 一种盐酸多奈哌齐新晶型及制备方法
CN107550884B (zh) * 2017-09-19 2018-06-05 扬子江药业集团上海海尼药业有限公司 一种盐酸多奈哌齐胶囊及其制备方法

Also Published As

Publication number Publication date
TR199802531T2 (xx) 1999-02-22
ATE230396T1 (de) 2003-01-15
CY2316B1 (en) 2003-11-14
NO20060377L (no) 1999-01-28
PL330362A1 (en) 1999-05-10
PT1019374E (pt) 2003-03-31
DE69718216T2 (de) 2003-10-09
DE69718216D1 (de) 2003-02-06
CN1221404A (zh) 1999-06-30
TWI243816B (en) 2005-11-21
CN1207282C (zh) 2005-06-22
CZ396098A3 (cs) 1999-03-17
CZ296619B6 (cs) 2006-05-17

Similar Documents

Publication Publication Date Title
HK1080078A1 (en) Polymorphs of donepezil hydrochloride and process for production
CA2252806A1 (en) Polymorphs of donepezil hydrochloride and process for production
NO20060377L (no) Polymorfer av donepezilhydroklorid og fremgangsmater for deres fremstilling
NO2004004I1 (no) Bortezomib eller en farmasøytisk akseptabel ester derav, eventuelt i form av et farmasøytisk akseptabelt salt derav
BR9612018A (pt) Processos e intermediários para preparação de 1-benzil-4- ((5,6-dimetóxi-1-indanon)-2-il)metilpiperid ina
DK0734260T4 (da) Paroxetintabletter og fremgangsmåde til fremstilling deraf
NO962896D0 (no) Fremgangsmåte for fremstilling av et titandioksydpigment og pigmentet oppnådd derved
NO983261L (no) Nye benzoylguanidin-derivater, fremgangsmåte ved fremstilling av dem og anvendelse av dem ved fremstilling av medisiner
HU9600624D0 (en) Piperidine derivatives, process for producing them and their pharmaceutical use
TW362096B (en) Novel piperidine derivatives and the process for preparing the same
NO970023D0 (no) Fremgangsmåte for fremstilling av en anatase-titandioksyd, og anatase-titandioksyd oppnådd derved
HUP0002270A2 (hu) Donepezil-hidroklorid polimorf módosulatai, eljárás ezek előállítására, valamint e módosulatokat tartalmazó gyógyászati készítmények
EE04235B1 (et) Toimeainete, nimelt tetrahüdropüridiinide ja atsetüülkoliinesteraasi inhibiitorite, kombinatsioon Alzheimeri tõve tüüpi seniildementsuse raviks
DE69330114T2 (de) Methandiphosphonat-derivat, dessen produktion und dessen verwendung als arzneimittel
RU93004477A (ru) Способ термохимического разложения закиси азота
PL303978A1 (en) Novel derivatives of piperidine and piperazine, method of obtaining them as well as pharmaceutical preparation and method of obtaining same
FI941480A0 (fi) 1,2,5,6-tetrahydropyridiinijohdannainen, menetelmä sen valmistamiseksi ja sen käyttö terapiassa
CA2286914A1 (en) Process for producing 1-chlorocarbonyl-4-piperidinopiperidine or hydrochloride thereof
RU93046413A (ru) Производные пиперидина, способ их получения и фармацевтическая композиция на их основе
IT8812021A0 (it) Elementi per l'isolamento e l'assorbimento acustico e termico negli edifici, nonche' per il fonoisolamento e l'assorbimento acustico negli spazi aperti
ITMI911911A1 (it) Lastre composite anche ornamentali e di sicurezza, e procedimento per la produzione delle stesse
TR27566A (tr) Konut ve sanayi kullanimli büyük kapilarin imalatinda ve bina ici bölmelerde kullanilan yüksek nitelikli panolar ve bunlarin imalatinda kullanilan yöntemler.
ITTV930079A0 (it) Procedimento perfezionato per la realizzazione di laminato plastico, e laminato cosi' ottenuto, particolarmente per rivestimento di antine per mobili
ITPD930027U1 (it) Profilato in alluminio estruso, di contenimento perimetrale per pannelli in genere nelle chiusure industriali: portoni ad impacco