TR200103067T2 - Renin inhibitörleri - Google Patents
Renin inhibitörleriInfo
- Publication number
- TR200103067T2 TR200103067T2 TR2001/03067T TR200103067T TR200103067T2 TR 200103067 T2 TR200103067 T2 TR 200103067T2 TR 2001/03067 T TR2001/03067 T TR 2001/03067T TR 200103067 T TR200103067 T TR 200103067T TR 200103067 T2 TR200103067 T2 TR 200103067T2
- Authority
- TR
- Turkey
- Prior art keywords
- renin inhibitors
- glaucoma
- restenosis
- combinations
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Bu bulus formül (I) bilesimleri ve bunlarin farmasötik açidan kabul edilebilir tuzlari ile ilgilidir ki burada R1 ve R2 tarifname ve istemlerde tarif edildikleri gibidirler. Bilesimler, restenoz, glokoma, kardiyak enfarktüs, yüksek basinci ve sonucu organ hasarlari, örn. kalp yetmezligi ve böbrek yetmezligi ile baglantili hastaliklarin tedavisi için kullanislidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99108200 | 1999-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200103067T2 true TR200103067T2 (tr) | 2002-05-21 |
Family
ID=8238051
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/03067T TR200103067T2 (tr) | 1999-04-27 | 2000-04-20 | Renin inhibitörleri |
Country Status (22)
Country | Link |
---|---|
US (1) | US6197959B1 (tr) |
EP (1) | EP1180103B1 (tr) |
JP (1) | JP3602449B2 (tr) |
KR (1) | KR100476916B1 (tr) |
CN (1) | CN1323079C (tr) |
AR (1) | AR018717A1 (tr) |
AT (1) | ATE363478T1 (tr) |
AU (1) | AU761392B2 (tr) |
BR (1) | BR0010076A (tr) |
CA (1) | CA2370244C (tr) |
CO (1) | CO5170512A1 (tr) |
CZ (1) | CZ20013737A3 (tr) |
DE (1) | DE60035039T2 (tr) |
ES (1) | ES2286021T3 (tr) |
HU (1) | HUP0200881A3 (tr) |
MX (1) | MXPA01010855A (tr) |
PE (1) | PE20010068A1 (tr) |
PL (1) | PL362903A1 (tr) |
SK (1) | SK15172001A3 (tr) |
TR (1) | TR200103067T2 (tr) |
WO (1) | WO2000064887A1 (tr) |
ZA (1) | ZA200108739B (tr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040214832A1 (en) * | 2003-04-10 | 2004-10-28 | Cuiman Cai | Piperazine derivative renin inhibitors |
TW200900399A (en) * | 2003-10-01 | 2009-01-01 | Speedel Experimenta Ag | Organic compounds |
AR045950A1 (es) * | 2003-10-09 | 2005-11-16 | Speedel Experimenta Ag | Compuestos derivados de piperazina, composiciones farmaceuticas que los contienen y su uso en la fabricacion de medicamentos. |
AU2004293177B2 (en) * | 2003-11-26 | 2008-10-23 | Novartis Ag | 4-phenylpiperidine derivatives as renin inhibitors |
TW200613274A (en) * | 2004-07-09 | 2006-05-01 | Speedel Experimenta Ag | Organic compounds |
CA2580862A1 (en) | 2004-10-08 | 2006-04-20 | Novartis Ag | Use of renin inhibitors for the prevention or treatment of diastolic dysfunction or diastolic heart failure |
GB0428526D0 (en) * | 2004-12-30 | 2005-02-09 | Novartis Ag | Organic compounds |
GB0500784D0 (en) * | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
AR053836A1 (es) * | 2005-03-31 | 2007-05-23 | Speedel Experimenta Ag | Piperdinas 3,4,5-sustituidas |
EP1707202A1 (de) * | 2005-03-31 | 2006-10-04 | Speedel Experimenta AG | Organische Verbindungen |
ES2352564T3 (es) * | 2005-03-31 | 2011-02-21 | Novartis Ag | Piperidinas sustituidas. |
EP1897879A3 (en) * | 2005-03-31 | 2008-06-11 | Speedel Experimenta AG | 2,4,5-substituted piperidines as renin inhibitors |
TW200833687A (en) * | 2005-03-31 | 2008-08-16 | Speedel Experimenta Ag | Substituted piperidines |
GB0508992D0 (en) * | 2005-05-03 | 2005-06-08 | Novartis Ag | Organic compounds |
JP5306811B2 (ja) * | 2005-05-11 | 2013-10-02 | ライフ テクノロジーズ コーポレーション | 2本鎖dnaへの高い選択性を有する蛍光化学物質及びそれらの使用 |
KR100963455B1 (ko) | 2005-05-27 | 2010-06-18 | 액테리온 파마슈티칼 리미티드 | 신규한 피페리딘 카르복실산 아미드 유도체 |
GB0514203D0 (en) * | 2005-07-11 | 2005-08-17 | Novartis Ag | Organic compounds |
US8129411B2 (en) * | 2005-12-30 | 2012-03-06 | Novartis Ag | Organic compounds |
TW200804359A (en) * | 2006-01-19 | 2008-01-16 | Speedel Experimenta Ag | Substituted 4-phenylpiperidines |
EP1908761A1 (en) * | 2006-10-04 | 2008-04-09 | Speedel Experimenta AG | Organic compounds |
BRPI0813900A2 (pt) | 2007-06-25 | 2014-12-30 | Novartis Ag | Derivados de n5-(2-etoxietil)-n3-(2-piridinil)-3,5-piperidinodicarboxa mida para uso como inibidores de renina |
AU2008320806A1 (en) * | 2007-11-02 | 2009-05-07 | Novartis Ag | 4,4-disubstituted piperidines as renin inhibitors |
SG175877A1 (en) * | 2009-05-04 | 2011-12-29 | Plexxikon Inc | Compounds and methods for inhibition of renin, and indications therefor |
WO2013045505A1 (en) | 2011-09-28 | 2013-04-04 | Novartis Ag | Biomarkers for raas combination therapy |
EP2810644A1 (en) | 2013-06-06 | 2014-12-10 | Ferrer Internacional, S.A. | Oral formulation for the treatment of cardiovascular diseases |
WO2018002673A1 (en) | 2016-07-01 | 2018-01-04 | N4 Pharma Uk Limited | Novel formulations of angiotensin ii receptor antagonists |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997009311A1 (de) * | 1995-09-07 | 1997-03-13 | F. Hoffmann-La Roche Ag | Neue 4-(oxyalkoxyphenyl)-3-oxy-piperidine zur behandlung von herz- und niereninsuffizienz |
-
2000
- 2000-04-04 US US09/542,598 patent/US6197959B1/en not_active Expired - Fee Related
- 2000-04-20 JP JP2000614239A patent/JP3602449B2/ja not_active Expired - Fee Related
- 2000-04-20 DE DE60035039T patent/DE60035039T2/de not_active Expired - Fee Related
- 2000-04-20 CA CA002370244A patent/CA2370244C/en not_active Expired - Fee Related
- 2000-04-20 HU HU0200881A patent/HUP0200881A3/hu unknown
- 2000-04-20 ES ES00929401T patent/ES2286021T3/es not_active Expired - Lifetime
- 2000-04-20 PL PL00362903A patent/PL362903A1/xx unknown
- 2000-04-20 TR TR2001/03067T patent/TR200103067T2/tr unknown
- 2000-04-20 BR BR0010076-5A patent/BR0010076A/pt not_active IP Right Cessation
- 2000-04-20 WO PCT/EP2000/003597 patent/WO2000064887A1/en not_active Application Discontinuation
- 2000-04-20 KR KR10-2001-7013726A patent/KR100476916B1/ko not_active IP Right Cessation
- 2000-04-20 SK SK1517-2001A patent/SK15172001A3/sk unknown
- 2000-04-20 CZ CZ20013737A patent/CZ20013737A3/cs unknown
- 2000-04-20 CN CNB008067988A patent/CN1323079C/zh not_active Expired - Fee Related
- 2000-04-20 AT AT00929401T patent/ATE363478T1/de not_active IP Right Cessation
- 2000-04-20 AU AU47501/00A patent/AU761392B2/en not_active Ceased
- 2000-04-20 MX MXPA01010855A patent/MXPA01010855A/es active IP Right Grant
- 2000-04-20 EP EP00929401A patent/EP1180103B1/en not_active Expired - Lifetime
- 2000-04-24 PE PE2000000377A patent/PE20010068A1/es not_active Application Discontinuation
- 2000-04-25 AR ARP000101933A patent/AR018717A1/es active IP Right Grant
- 2000-04-25 CO CO00029684A patent/CO5170512A1/es not_active Application Discontinuation
-
2001
- 2001-10-23 ZA ZA200108739A patent/ZA200108739B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2002543072A (ja) | 2002-12-17 |
AU761392B2 (en) | 2003-06-05 |
DE60035039T2 (de) | 2008-02-07 |
KR100476916B1 (ko) | 2005-03-17 |
PL362903A1 (en) | 2004-11-02 |
SK15172001A3 (sk) | 2002-06-04 |
CO5170512A1 (es) | 2002-06-27 |
AU4750100A (en) | 2000-11-10 |
HUP0200881A2 (en) | 2002-08-28 |
ES2286021T3 (es) | 2007-12-01 |
EP1180103A1 (en) | 2002-02-20 |
CA2370244C (en) | 2007-03-27 |
DE60035039D1 (de) | 2007-07-12 |
JP3602449B2 (ja) | 2004-12-15 |
CA2370244A1 (en) | 2000-11-02 |
EP1180103B1 (en) | 2007-05-30 |
KR20020005017A (ko) | 2002-01-16 |
CZ20013737A3 (cs) | 2002-04-17 |
US6197959B1 (en) | 2001-03-06 |
ATE363478T1 (de) | 2007-06-15 |
HUP0200881A3 (en) | 2003-05-28 |
CN1323079C (zh) | 2007-06-27 |
MXPA01010855A (es) | 2002-05-06 |
ZA200108739B (en) | 2003-01-23 |
CN1349524A (zh) | 2002-05-15 |
WO2000064887A1 (en) | 2000-11-02 |
PE20010068A1 (es) | 2001-01-29 |
AR018717A1 (es) | 2001-11-28 |
BR0010076A (pt) | 2002-01-15 |
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