TR200102730T2 - Doksazosin-mesilatın kristal modifikasyonda üretimine yönelik yeni yöntem. - Google Patents

Doksazosin-mesilatın kristal modifikasyonda üretimine yönelik yeni yöntem.

Info

Publication number
TR200102730T2
TR200102730T2 TR2001/02730T TR200102730T TR200102730T2 TR 200102730 T2 TR200102730 T2 TR 200102730T2 TR 2001/02730 T TR2001/02730 T TR 2001/02730T TR 200102730 T TR200102730 T TR 200102730T TR 200102730 T2 TR200102730 T2 TR 200102730T2
Authority
TR
Turkey
Prior art keywords
production
doxazosin
new method
crystal modification
doxazosin mesylate
Prior art date
Application number
TR2001/02730T
Other languages
English (en)
Turkish (tr)
Inventor
Klein Peter
Thyes Mar�O
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of TR200102730T2 publication Critical patent/TR200102730T2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
TR2001/02730T 1999-03-18 2000-03-06 Doksazosin-mesilatın kristal modifikasyonda üretimine yönelik yeni yöntem. TR200102730T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19912063A DE19912063A1 (de) 1999-03-18 1999-03-18 Neues Verfahren zur Herstellung von Doxazosin-Mesylat in einer als Form A bezeichneten Kristallmodifikation

Publications (1)

Publication Number Publication Date
TR200102730T2 true TR200102730T2 (tr) 2002-06-21

Family

ID=7901411

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02730T TR200102730T2 (tr) 1999-03-18 2000-03-06 Doksazosin-mesilatın kristal modifikasyonda üretimine yönelik yeni yöntem.

Country Status (13)

Country Link
EP (1) EP1165548A1 (ja)
JP (1) JP2002540109A (ja)
KR (1) KR20010113753A (ja)
CN (1) CN1352643A (ja)
AU (1) AU3960800A (ja)
CA (1) CA2367903A1 (ja)
CZ (1) CZ20013347A3 (ja)
DE (1) DE19912063A1 (ja)
HU (1) HUP0200663A2 (ja)
IL (1) IL144944A0 (ja)
PL (1) PL350088A1 (ja)
TR (1) TR200102730T2 (ja)
WO (1) WO2000056731A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19912573A1 (de) * 1999-03-19 2000-09-21 Knoll Ag Arzneimittel, enthaltend Doxazosin-Mesylat der Kristallmodifikaton D
NZ585558A (en) 2007-12-24 2011-08-26 Cipla Ltd Crystalline polymorph of doxazosin mesylate (form iv) and process for preparation thereof
CN109988158A (zh) * 2018-01-03 2019-07-09 合肥立方制药股份有限公司 X晶型、含有x晶型的多沙唑嗪甲磺酸盐及其制备方法和用途
CN111303130B (zh) * 2018-12-11 2021-09-14 合肥立方制药股份有限公司 一种多沙唑嗪甲磺酸盐晶型、其制备方法及用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1287588B1 (it) * 1996-12-13 1998-08-06 Alfa Chem Ital Forma cristallina del doxazosin mesilato e processo per la sua produzione
PT849266E (pt) * 1996-12-20 2007-03-30 Heumann Pcs Gmbh Nova forma polimorfa de mesilato de doxazosina (forma iii)
DE19800214A1 (de) * 1998-01-06 1999-07-15 Knoll Ag Verfahren zur Herstellung von Doxazosin-Mcsylat in einer als Form A bezeichneten Kristallmodifikation und ein Zwischenprodukt dafür

Also Published As

Publication number Publication date
CN1352643A (zh) 2002-06-05
CZ20013347A3 (cs) 2002-01-16
KR20010113753A (ko) 2001-12-28
PL350088A1 (en) 2002-11-04
WO2000056731A1 (de) 2000-09-28
JP2002540109A (ja) 2002-11-26
AU3960800A (en) 2000-10-09
DE19912063A1 (de) 2000-09-21
IL144944A0 (en) 2002-06-30
HUP0200663A2 (en) 2002-08-28
CA2367903A1 (en) 2000-09-28
EP1165548A1 (de) 2002-01-02

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