DE60007716D1 - Verfahren zur gewinnung von 17beta-(n-tert-butylcarbamoyl)-3-on-4-aza-steroiden - Google Patents

Verfahren zur gewinnung von 17beta-(n-tert-butylcarbamoyl)-3-on-4-aza-steroiden

Info

Publication number
DE60007716D1
DE60007716D1 DE60007716T DE60007716T DE60007716D1 DE 60007716 D1 DE60007716 D1 DE 60007716D1 DE 60007716 T DE60007716 T DE 60007716T DE 60007716 T DE60007716 T DE 60007716T DE 60007716 D1 DE60007716 D1 DE 60007716D1
Authority
DE
Germany
Prior art keywords
tert
butylcarbamoyl
17beta
obtaining
aza
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60007716T
Other languages
English (en)
Other versions
DE60007716T2 (de
Inventor
Guisasola Luis Octavio Silva
Fernandez Cristina Blanco
Bonde-Larsen Antonio Lorente
Juarez Jorge Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ragactives SL
Original Assignee
Ragactives SL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ragactives SL filed Critical Ragactives SL
Publication of DE60007716D1 publication Critical patent/DE60007716D1/de
Application granted granted Critical
Publication of DE60007716T2 publication Critical patent/DE60007716T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
DE60007716T 1999-07-05 2000-07-05 Verfahren zur gewinnung von 17beta-(n-tert-butylcarbamoyl)-3-on-4-aza-steroiden Expired - Fee Related DE60007716T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES009901487A ES2153789B1 (es) 1999-07-05 1999-07-05 Procedimiento para la obtencion de 178-(n-terc-butlcarbamoil)-3-ona-4-aza-esteroides
ES9901487 1999-07-05
PCT/ES2000/000239 WO2001002422A1 (es) 1999-07-05 2000-07-05 PROCEDIMIENTO PARA LA OBTENCION DE 17β-(N-TERC-BUTILCARBAMOIL)-3-ONA-4-AZA-ESTEROIDES

Publications (2)

Publication Number Publication Date
DE60007716D1 true DE60007716D1 (de) 2004-02-19
DE60007716T2 DE60007716T2 (de) 2004-12-09

Family

ID=8309089

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60007716T Expired - Fee Related DE60007716T2 (de) 1999-07-05 2000-07-05 Verfahren zur gewinnung von 17beta-(n-tert-butylcarbamoyl)-3-on-4-aza-steroiden

Country Status (9)

Country Link
US (1) US6509466B2 (de)
EP (1) EP1116725B1 (de)
JP (1) JP2003503507A (de)
AT (1) ATE257842T1 (de)
CA (1) CA2342864A1 (de)
DE (1) DE60007716T2 (de)
ES (1) ES2153789B1 (de)
HU (1) HUP0103002A3 (de)
WO (1) WO2001002422A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100415858B1 (ko) * 2001-09-22 2004-01-24 한미약품 주식회사 17베타-(엔-3차-부틸카바모일)-3-온 스테로이드 화합물의제조방법
US10351615B2 (en) 2006-02-03 2019-07-16 Opko Biologics Ltd. Methods of treatment with long-acting growth hormone
US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
FR3106058B1 (fr) * 2020-01-09 2022-01-07 Oreal Procédé de traitement cosmétique
CN114213502B (zh) * 2021-12-08 2024-02-13 湖南醇健制药科技有限公司 一种非那雄胺的精制方法及非那雄胺制剂和其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760071A (en) 1984-02-27 1988-07-26 Merck & Co., Inc. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
US5237061A (en) * 1988-10-31 1993-08-17 Merck & Co., Inc. Methods of synthesizing benign prostatic hypertropic agents and their intermediates
US5468860A (en) * 1992-11-19 1995-11-21 Merck & Co., Inc. New finasteride processes
DK0705272T3 (da) * 1993-06-24 2002-05-27 Richter Gedeon Vegyeszet Særlig fremgangsmåde til fremstilling af 17beta-substituerede 4-azaandrostanderivater
US5670643A (en) * 1995-03-16 1997-09-23 Glaxo Wellcome Inc. Method for preparing finasteride
GB2338234B (en) * 1998-06-10 2000-05-03 Torcan Chemical Ltd Preparation of finasteride

Also Published As

Publication number Publication date
JP2003503507A (ja) 2003-01-28
DE60007716T2 (de) 2004-12-09
ATE257842T1 (de) 2004-01-15
EP1116725A1 (de) 2001-07-18
ES2153789A1 (es) 2001-03-01
US6509466B2 (en) 2003-01-21
WO2001002422A9 (es) 2001-04-05
EP1116725B1 (de) 2004-01-14
ES2153789B1 (es) 2001-10-16
CA2342864A1 (en) 2001-01-11
US20010008895A1 (en) 2001-07-19
HUP0103002A2 (hu) 2002-01-28
HUP0103002A3 (en) 2002-09-30
WO2001002422A1 (es) 2001-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee