TR200101443T2 - 8-siyano-1-siklopropil-7- (1S,6S-2,8-diazabisiklo[4,3,0]-nonan-8-il) -6-flüoro-1, 4-dihidro-4-okso-3-kinolinkarboksilik asidin yarı-hidroklorürü - Google Patents

8-siyano-1-siklopropil-7- (1S,6S-2,8-diazabisiklo[4,3,0]-nonan-8-il) -6-flüoro-1, 4-dihidro-4-okso-3-kinolinkarboksilik asidin yarı-hidroklorürü

Info

Publication number
TR200101443T2
TR200101443T2 TR2001/01443T TR200101443T TR200101443T2 TR 200101443 T2 TR200101443 T2 TR 200101443T2 TR 2001/01443 T TR2001/01443 T TR 2001/01443T TR 200101443 T TR200101443 T TR 200101443T TR 200101443 T2 TR200101443 T2 TR 200101443T2
Authority
TR
Turkey
Prior art keywords
nonan
diazabicyclo
dihydro
oxo
fluoro
Prior art date
Application number
TR2001/01443T
Other languages
English (en)
Inventor
Himmler Thomas
Rast Hubert
Original Assignee
Bayer Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag. filed Critical Bayer Ag.
Publication of TR200101443T2 publication Critical patent/TR200101443T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Bu bulus, 8-siyano-1siklopropil-7- (1S,6S-2,8-diazabisiklo[4.3.0]nonan-8-il)-6-flüoro-1, 4-dihidro-4-okso-3-kinolin-karboksilik asidin bir yari-hidroklorürüne, bunun hazirlanmasi için islemlere ve bunu içeren antibakteriyel bilesimlere iliskindir. 8-siyano-1-siklopropil-7- (1S,6S-2,8-diazabisiklo[4,3,0]nonan-8-il)-6-flüoro-1, 4-dihidro-4-okso-3-kinolinkarboksilik asit, asagidaki formül ile tanimlanabilir (FORMÜL).
TR2001/01443T 1998-11-25 1999-11-15 8-siyano-1-siklopropil-7- (1S,6S-2,8-diazabisiklo[4,3,0]-nonan-8-il) -6-flüoro-1, 4-dihidro-4-okso-3-kinolinkarboksilik asidin yarı-hidroklorürü TR200101443T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19854357A DE19854357A1 (de) 1998-11-25 1998-11-25 Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Publications (1)

Publication Number Publication Date
TR200101443T2 true TR200101443T2 (tr) 2001-09-21

Family

ID=7888961

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/01443T TR200101443T2 (tr) 1998-11-25 1999-11-15 8-siyano-1-siklopropil-7- (1S,6S-2,8-diazabisiklo[4,3,0]-nonan-8-il) -6-flüoro-1, 4-dihidro-4-okso-3-kinolinkarboksilik asidin yarı-hidroklorürü

Country Status (28)

Country Link
US (1) US6995170B1 (tr)
EP (1) EP1133495B1 (tr)
JP (1) JP2002530408A (tr)
KR (1) KR100740956B1 (tr)
CN (1) CN1176921C (tr)
AR (1) AR023709A1 (tr)
AT (1) ATE225790T1 (tr)
AU (1) AU759769B2 (tr)
BR (1) BR9915684A (tr)
CA (1) CA2351714C (tr)
CZ (1) CZ300058B6 (tr)
DE (2) DE19854357A1 (tr)
DK (1) DK1133495T3 (tr)
ES (1) ES2181488T3 (tr)
HK (1) HK1042704B (tr)
HU (1) HUP0104367A3 (tr)
IL (2) IL142837A0 (tr)
NO (1) NO318053B1 (tr)
NZ (1) NZ511863A (tr)
PL (1) PL196508B1 (tr)
PT (1) PT1133495E (tr)
RU (1) RU2242475C2 (tr)
SK (1) SK285561B6 (tr)
TR (1) TR200101443T2 (tr)
TW (1) TWI234565B (tr)
UA (1) UA67875C2 (tr)
WO (1) WO2000031077A1 (tr)
ZA (1) ZA013317B (tr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE10224086A1 (de) * 2002-05-31 2003-12-11 Bayer Ag Pharmazeutische Zubereitungen zur oralen Anwendung enthaltend wirkstoffbeladene Ionentauscherharze sowie strukturviskose Gelbildner als Verdicker
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin
WO2018146194A1 (en) 2017-02-13 2018-08-16 Bayer Animal Health Gmbh Liquid composition containing pradofloxacin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
DK0882049T3 (da) * 1996-02-23 2003-03-03 Bayer Ag Eventuelt substituerede 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyrer og deres derivater
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Also Published As

Publication number Publication date
NO318053B1 (no) 2005-01-24
PL196508B1 (pl) 2008-01-31
EP1133495B1 (de) 2002-10-09
BR9915684A (pt) 2001-08-14
CN1328557A (zh) 2001-12-26
AU1271600A (en) 2000-06-13
EP1133495A1 (de) 2001-09-19
DK1133495T3 (da) 2003-02-10
SK6842001A3 (en) 2001-12-03
ZA013317B (en) 2002-06-26
JP2002530408A (ja) 2002-09-17
US6995170B1 (en) 2006-02-07
IL142837A0 (en) 2002-03-10
CZ20011753A3 (cs) 2001-09-12
KR100740956B1 (ko) 2007-07-19
NO20012532D0 (no) 2001-05-23
ES2181488T3 (es) 2003-02-16
NO20012532L (no) 2001-07-02
KR20010075694A (ko) 2001-08-09
IL142837A (en) 2006-08-01
HK1042704A1 (en) 2002-08-23
DE59903063D1 (de) 2002-11-14
HK1042704B (zh) 2005-09-09
CA2351714C (en) 2010-06-15
TWI234565B (en) 2005-06-21
UA67875C2 (uk) 2004-07-15
PL347799A1 (en) 2002-04-22
CN1176921C (zh) 2004-11-24
HUP0104367A2 (hu) 2002-02-28
RU2242475C2 (ru) 2004-12-20
DE19854357A1 (de) 2000-05-31
PT1133495E (pt) 2003-02-28
CA2351714A1 (en) 2000-06-02
SK285561B6 (sk) 2007-03-01
WO2000031077A1 (de) 2000-06-02
ATE225790T1 (de) 2002-10-15
AR023709A1 (es) 2002-09-04
HUP0104367A3 (en) 2002-12-28
NZ511863A (en) 2003-05-30
CZ300058B6 (cs) 2009-01-21
AU759769B2 (en) 2003-05-01

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