TR200102435T2 - 8-siyano-1-siklopropil- (1S, 6S- 2,8- diazabisiklo-[4,3.0]nonan-8-il)-6- flüoro-1,4-dihidro-4-okso-3-kinolin karboksilik asidin kristal modifikasyonu D. - Google Patents

8-siyano-1-siklopropil- (1S, 6S- 2,8- diazabisiklo-[4,3.0]nonan-8-il)-6- flüoro-1,4-dihidro-4-okso-3-kinolin karboksilik asidin kristal modifikasyonu D.

Info

Publication number
TR200102435T2
TR200102435T2 TR2001/02435T TR200102435T TR200102435T2 TR 200102435 T2 TR200102435 T2 TR 200102435T2 TR 2001/02435 T TR2001/02435 T TR 2001/02435T TR 200102435 T TR200102435 T TR 200102435T TR 200102435 T2 TR200102435 T2 TR 200102435T2
Authority
TR
Turkey
Prior art keywords
nonan
diazabicyclo
cyclopropyl
dihydro
oxo
Prior art date
Application number
TR2001/02435T
Other languages
English (en)
Inventor
Himmler Thomas
Rast Hubert
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of TR200102435T2 publication Critical patent/TR200102435T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

(FORMÜL) Bu bulus, 8-siyano-1-siklopropil-7- (1S,6S-2,8-diazabisiklo [4.3.0]nonan-8-il)-6- flüoro-1, 4-dihidro-4-okso-3- kinolinkarboksilik asidin tanimlanmis bir kristal modifikasyonuna, bunun hazirlanmasi için islemlere ve farmasötik preparatlarin hazirlanmasinda kullanilmasina iliskindir. Kristal modifikasyonu, karakteristik X-isini toz kirinim çizelgesiyle ve diferansiyel termodiyagramiyla,8-siyano-1-siklopropil-7- (1S,6S-2.8-diazabisiklo [4.3.0]nonan-8-il)-6-flüoro-1, 4-dihidro-4-okso-3- kinolinkarboksilik asidin diger kristal modifikasyonlarindan ayirt edilebilir.
TR2001/02435T 1999-02-26 2000-02-14 8-siyano-1-siklopropil- (1S, 6S- 2,8- diazabisiklo-[4,3.0]nonan-8-il)-6- flüoro-1,4-dihidro-4-okso-3-kinolin karboksilik asidin kristal modifikasyonu D. TR200102435T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19908448A DE19908448A1 (de) 1999-02-26 1999-02-26 Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure

Publications (1)

Publication Number Publication Date
TR200102435T2 true TR200102435T2 (tr) 2002-01-21

Family

ID=7899026

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02435T TR200102435T2 (tr) 1999-02-26 2000-02-14 8-siyano-1-siklopropil- (1S, 6S- 2,8- diazabisiklo-[4,3.0]nonan-8-il)-6- flüoro-1,4-dihidro-4-okso-3-kinolin karboksilik asidin kristal modifikasyonu D.

Country Status (22)

Country Link
US (1) US6492391B1 (tr)
EP (1) EP1159277A1 (tr)
JP (1) JP2002538159A (tr)
KR (1) KR100756474B1 (tr)
CN (1) CN1217944C (tr)
AU (1) AU760710B2 (tr)
BR (1) BR0008520A (tr)
CA (1) CA2362804A1 (tr)
CZ (1) CZ20013065A3 (tr)
DE (1) DE19908448A1 (tr)
HK (1) HK1045158B (tr)
HU (1) HUP0200053A3 (tr)
IL (1) IL144528A0 (tr)
NO (1) NO320314B1 (tr)
NZ (1) NZ513749A (tr)
PL (1) PL349394A1 (tr)
RU (1) RU2248357C2 (tr)
SK (1) SK11942001A3 (tr)
TR (1) TR200102435T2 (tr)
UA (1) UA71606C2 (tr)
WO (1) WO2000052010A1 (tr)
ZA (1) ZA200106050B (tr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
AU2018217931B2 (en) 2017-02-13 2023-04-13 Elanco Animal Health Gmbh Liquid composition containing pradofloxacin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2676521B2 (ja) * 1988-03-22 1997-11-17 北陸製薬株式会社 キノロンカルボン酸化合物ｉ型結晶の製造法
MX9703622A (es) * 1994-11-18 1997-08-30 Upjohn Co Una nueva forma solida fisicamente estable en una fluoroquinolona.
JP4338217B2 (ja) * 1996-02-23 2009-10-07 バイエル・アニマル・ヘルス・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 置換可能な８―シアノ―１―シクロプロピル―７―（２，８―ジアザビシクロ―［４．３．０］―ノナン―８―イル）―６―フルオロ―１，４―ジヒドロ―４―オキソ―３―キノリンカルボン酸およびそれらの誘導体
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
JP2001242582A (ja) * 2000-02-25 2001-09-07 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料およびその現像処理方法

Also Published As

Publication number Publication date
BR0008520A (pt) 2001-12-18
CZ20013065A3 (cs) 2002-01-16
AU3154400A (en) 2000-09-21
IL144528A0 (en) 2002-05-23
JP2002538159A (ja) 2002-11-12
PL349394A1 (en) 2002-07-15
CN1341116A (zh) 2002-03-20
NZ513749A (en) 2003-10-31
ZA200106050B (en) 2002-07-24
RU2248357C2 (ru) 2005-03-20
WO2000052010A1 (de) 2000-09-08
HK1045158B (zh) 2006-04-21
HUP0200053A2 (hu) 2002-05-29
SK11942001A3 (sk) 2001-12-03
NO20014059D0 (no) 2001-08-21
UA71606C2 (uk) 2004-12-15
EP1159277A1 (de) 2001-12-05
KR100756474B1 (ko) 2007-09-07
AU760710B2 (en) 2003-05-22
HK1045158A1 (en) 2002-11-15
HUP0200053A3 (en) 2003-01-28
CA2362804A1 (en) 2000-09-08
NO320314B1 (no) 2005-11-21
KR20010093300A (ko) 2001-10-27
NO20014059L (no) 2001-08-21
US6492391B1 (en) 2002-12-10
DE19908448A1 (de) 2000-08-31
CN1217944C (zh) 2005-09-07

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