HK1045158B - 8-氰基-1-環丙基-7-(1s，6s-2，8-二氮雜雙環[4‧3‧0]壬-8-基)-6-氟-1，4-二氫-4-氧代-3-喹啉羧酸的結晶變體d - Google Patents

8-氰基-1-環丙基-7-(1s，6s-2，8-二氮雜雙環[4‧3‧0]壬-8-基)-6-氟-1，4-二氫-4-氧代-3-喹啉羧酸的結晶變體d

Info

Publication number
HK1045158B
HK1045158B HK02106690.8A HK02106690A HK1045158B HK 1045158 B HK1045158 B HK 1045158B HK 02106690 A HK02106690 A HK 02106690A HK 1045158 B HK1045158 B HK 1045158B
Authority
HK
Hong Kong
Prior art keywords
nonan
diazabicyclo
cyclopropyl
dihydro
oxo
Prior art date
Application number
HK02106690.8A
Other languages
English (en)
Other versions
HK1045158A1 (en
Inventor
Himmler Thomas
Rast Hubert
Original Assignee
拜爾公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 拜爾公司 filed Critical 拜爾公司
Publication of HK1045158A1 publication Critical patent/HK1045158A1/xx
Publication of HK1045158B publication Critical patent/HK1045158B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK02106690.8A 1999-02-26 2002-09-12 8-氰基-1-環丙基-7-(1s，6s-2，8-二氮雜雙環[4‧3‧0]壬-8-基)-6-氟-1，4-二氫-4-氧代-3-喹啉羧酸的結晶變體d HK1045158B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19908448A DE19908448A1 (de) 1999-02-26 1999-02-26 Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
PCT/EP2000/001203 WO2000052010A1 (de) 1999-02-26 2000-02-14 Kristallmodifikation d von 8-cyan-1-cyclopropyl-7- (1s, 6s- 2,8- diazabicyclo- [4.3.0] nonan -8-yl) -6-fluor -1,4- dihydro -4-oxo -3-c hinolincarbonsäure

Publications (2)

Publication Number Publication Date
HK1045158A1 HK1045158A1 (en) 2002-11-15
HK1045158B true HK1045158B (zh) 2006-04-21

Family

ID=7899026

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02106690.8A HK1045158B (zh) 1999-02-26 2002-09-12 8-氰基-1-環丙基-7-(1s，6s-2，8-二氮雜雙環[4‧3‧0]壬-8-基)-6-氟-1，4-二氫-4-氧代-3-喹啉羧酸的結晶變體d

Country Status (22)

Country Link
US (1) US6492391B1 (zh)
EP (1) EP1159277A1 (zh)
JP (1) JP2002538159A (zh)
KR (1) KR100756474B1 (zh)
CN (1) CN1217944C (zh)
AU (1) AU760710B2 (zh)
BR (1) BR0008520A (zh)
CA (1) CA2362804A1 (zh)
CZ (1) CZ20013065A3 (zh)
DE (1) DE19908448A1 (zh)
HK (1) HK1045158B (zh)
HU (1) HUP0200053A3 (zh)
IL (1) IL144528A0 (zh)
NO (1) NO320314B1 (zh)
NZ (1) NZ513749A (zh)
PL (1) PL349394A1 (zh)
RU (1) RU2248357C2 (zh)
SK (1) SK11942001A3 (zh)
TR (1) TR200102435T2 (zh)
UA (1) UA71606C2 (zh)
WO (1) WO2000052010A1 (zh)
ZA (1) ZA200106050B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
RU2019128568A (ru) 2017-02-13 2021-03-15 Байер Энимэл Хельс ГмбХ Жидкая композиция, содержащая прадофлоксацин

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2676521B2 (ja) * 1988-03-22 1997-11-17 北陸製薬株式会社 キノロンカルボン酸化合物ｉ型結晶の製造法
AU709057B2 (en) * 1994-11-18 1999-08-19 Pharmacia & Upjohn Company A new physically stable solid form of a fluoroquinolone
DE59708771D1 (de) * 1996-02-23 2003-01-02 Bayer Ag Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
JP2001242582A (ja) * 2000-02-25 2001-09-07 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料およびその現像処理方法

Also Published As

Publication number Publication date
WO2000052010A1 (de) 2000-09-08
CN1341116A (zh) 2002-03-20
AU3154400A (en) 2000-09-21
DE19908448A1 (de) 2000-08-31
PL349394A1 (en) 2002-07-15
CZ20013065A3 (cs) 2002-01-16
HUP0200053A3 (en) 2003-01-28
HUP0200053A2 (hu) 2002-05-29
NO320314B1 (no) 2005-11-21
NZ513749A (en) 2003-10-31
RU2248357C2 (ru) 2005-03-20
BR0008520A (pt) 2001-12-18
EP1159277A1 (de) 2001-12-05
JP2002538159A (ja) 2002-11-12
KR20010093300A (ko) 2001-10-27
UA71606C2 (uk) 2004-12-15
SK11942001A3 (sk) 2001-12-03
HK1045158A1 (en) 2002-11-15
NO20014059L (no) 2001-08-21
US6492391B1 (en) 2002-12-10
KR100756474B1 (ko) 2007-09-07
CA2362804A1 (en) 2000-09-08
AU760710B2 (en) 2003-05-22
IL144528A0 (en) 2002-05-23
ZA200106050B (en) 2002-07-24
CN1217944C (zh) 2005-09-07
TR200102435T2 (tr) 2002-01-21
NO20014059D0 (no) 2001-08-21

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100214