TR199902883T2 - NK-2 ve NK-3 reseptör antagonistleri olarak kuinolin-4-karboksamid türevleri. - Google Patents
NK-2 ve NK-3 reseptör antagonistleri olarak kuinolin-4-karboksamid türevleri.Info
- Publication number
- TR199902883T2 TR199902883T2 TR1999/02883T TR9902883T TR199902883T2 TR 199902883 T2 TR199902883 T2 TR 199902883T2 TR 1999/02883 T TR1999/02883 T TR 1999/02883T TR 9902883 T TR9902883 T TR 9902883T TR 199902883 T2 TR199902883 T2 TR 199902883T2
- Authority
- TR
- Turkey
- Prior art keywords
- quinoline
- receptor antagonists
- carboxamide derivatives
- compounds
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/48—Two nitrogen atoms
- C07D251/52—Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Abstract
Bu bulus, özellikle yeni kuinolin türevleri olmak üzere yeni bilesikler, bu gibi bilesiklerin hazirlanmasi için prosesler, bu gibi bilesikleri içeren farmasötik terkipler ve bu gibi terkiplerin tipta kullanimi ile ilgilidir. (Formül(I))
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9710750.2A GB9710750D0 (en) | 1997-05-23 | 1997-05-23 | Novel compounds |
IT002354 IT1295358B1 (it) | 1997-10-17 | 1997-10-17 | Derivati chinolinici procedimento per la loro preparazione e uso come antagonisti del recettore nk3 |
ITMI972775 IT1296976B1 (it) | 1997-12-16 | 1997-12-16 | Derivati chinolinici procedimento per la loro preparazione e uso come antagonisti del recettore nk3 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199902883T2 true TR199902883T2 (tr) | 2000-05-22 |
Family
ID=27268859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1999/02883T TR199902883T2 (tr) | 1997-05-23 | 1998-05-18 | NK-2 ve NK-3 reseptör antagonistleri olarak kuinolin-4-karboksamid türevleri. |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP0983262B1 (tr) |
JP (1) | JP2002500645A (tr) |
CN (1) | CN1264378A (tr) |
AP (1) | AP9901695A0 (tr) |
AR (1) | AR012732A1 (tr) |
AT (1) | ATE244711T1 (tr) |
AU (1) | AU8209898A (tr) |
BG (1) | BG104009A (tr) |
BR (1) | BR9809652A (tr) |
CA (1) | CA2291111A1 (tr) |
CO (1) | CO4950515A1 (tr) |
DE (1) | DE69816290T2 (tr) |
DZ (1) | DZ2498A1 (tr) |
EA (1) | EA199901062A1 (tr) |
ES (1) | ES2201509T3 (tr) |
HU (1) | HUP0002300A3 (tr) |
ID (1) | ID22876A (tr) |
IL (1) | IL133036A0 (tr) |
MA (1) | MA26501A1 (tr) |
NO (1) | NO995711L (tr) |
OA (1) | OA11515A (tr) |
PE (1) | PE75199A1 (tr) |
PL (1) | PL336942A1 (tr) |
SK (1) | SK159299A3 (tr) |
TR (1) | TR199902883T2 (tr) |
WO (1) | WO1998052942A1 (tr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9825554D0 (en) * | 1998-11-20 | 1999-01-13 | Smithkline Beecham Spa | Novel Compounds |
TR200101412T2 (tr) * | 1998-11-20 | 2001-10-22 | Smithkline Beecham S.P.A. | Yeni bileşikler. |
US6780875B2 (en) * | 1998-11-20 | 2004-08-24 | Smithkline Beecham S.P.A. | Quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists |
DE60004654T2 (de) | 1999-03-29 | 2004-06-24 | Neurogen Corp., Branford | 4-substituierte chinolinderivate als nk-3 und/oder gaba(a) rezeptor liganden |
AU4802500A (en) | 1999-04-26 | 2000-11-10 | Neurogen Corporation | 2-aminoquinolinecarboxamides: neurokinin receptor ligands |
AU2001276556A1 (en) * | 2000-08-11 | 2002-02-25 | Smithkline Beecham P.L.C. | Novel pharmaceutical use of quinnoline derivatives |
JP2004517062A (ja) * | 2000-11-13 | 2004-06-10 | グラクソスミスクライン・ソシエタ・ペル・アチオニ | Nk−3およびnk−2アンタゴニストとしてのキノリン誘導体 |
AU2002226356A1 (en) * | 2000-11-28 | 2002-06-11 | Glaxosmithkline S.P.A. | Quinoline derivatives as nk-3 antagonists |
GB0028964D0 (en) * | 2000-11-28 | 2001-01-10 | Smithkline Beecham Spa | Novel compounds |
US6540733B2 (en) | 2000-12-29 | 2003-04-01 | Corazon Technologies, Inc. | Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occlusion |
EP1659120A1 (en) * | 2001-04-11 | 2006-05-24 | GlaxoSmithKline S.p.A. | 3-substituted quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists |
GB0109122D0 (en) * | 2001-04-11 | 2001-05-30 | Smithkline Beecham Spa | Novel compounds |
MY134211A (en) * | 2001-05-18 | 2007-11-30 | Smithkline Beecham Corp | Novel use |
GB0425076D0 (en) * | 2004-11-12 | 2004-12-15 | Smithkline Beecham Corp | Novel compounds |
GB0425075D0 (en) * | 2004-11-12 | 2004-12-15 | Smithkline Beecham Corp | Novel compounds |
GB0425077D0 (en) * | 2004-11-12 | 2004-12-15 | Smithkline Beecham Corp | Novel compounds |
KR20080016591A (ko) * | 2005-06-03 | 2008-02-21 | 아스트라제네카 아베 | Nk3 길항제로서의 퀴놀린 유도체 |
GB0515580D0 (en) | 2005-07-29 | 2005-09-07 | Merck Sharp & Dohme | Therapeutic compounds |
AR057130A1 (es) | 2005-09-21 | 2007-11-14 | Astrazeneca Ab | Quinolinas de alquilsulfoxido y una composicion farmaceutica |
DE202007017299U1 (de) * | 2007-12-12 | 2009-04-23 | Drebo Werkzeugfabrik Gmbh | Bohrer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ291476B6 (cs) * | 1994-05-27 | 2003-03-12 | Smithkline Beecham S. P. A. | N-(alfa-Ethylbenzyl)-3-hydroxy-2-fenylchinolin-4-karboxamid, farmaceutický prostředek s jeho obsahem a použití |
AR004735A1 (es) * | 1995-11-24 | 1999-03-10 | Smithkline Beecham Spa | Quinoleina 4-amido sustituida, un procedimiento para su preparacion, una composicion farmaceutica que los contiene y el uso de los mismos para lapreparacion de un medicamento. |
-
1998
- 1998-05-18 BR BR9809652-4A patent/BR9809652A/pt not_active IP Right Cessation
- 1998-05-18 WO PCT/EP1998/003014 patent/WO1998052942A1/en not_active Application Discontinuation
- 1998-05-18 AU AU82098/98A patent/AU8209898A/en not_active Abandoned
- 1998-05-18 EP EP98932069A patent/EP0983262B1/en not_active Expired - Lifetime
- 1998-05-18 AT AT98932069T patent/ATE244711T1/de not_active IP Right Cessation
- 1998-05-18 EA EA199901062A patent/EA199901062A1/ru unknown
- 1998-05-18 HU HU0002300A patent/HUP0002300A3/hu unknown
- 1998-05-18 PL PL98336942A patent/PL336942A1/xx unknown
- 1998-05-18 AP APAP/P/1999/001695A patent/AP9901695A0/en unknown
- 1998-05-18 CA CA002291111A patent/CA2291111A1/en not_active Abandoned
- 1998-05-18 ES ES98932069T patent/ES2201509T3/es not_active Expired - Lifetime
- 1998-05-18 ID IDW991432A patent/ID22876A/id unknown
- 1998-05-18 IL IL13303698A patent/IL133036A0/xx unknown
- 1998-05-18 CN CN98807356A patent/CN1264378A/zh active Pending
- 1998-05-18 SK SK1592-99A patent/SK159299A3/sk unknown
- 1998-05-18 DE DE69816290T patent/DE69816290T2/de not_active Expired - Fee Related
- 1998-05-18 TR TR1999/02883T patent/TR199902883T2/tr unknown
- 1998-05-18 JP JP54996798A patent/JP2002500645A/ja not_active Ceased
- 1998-05-19 DZ DZ980108A patent/DZ2498A1/xx active
- 1998-05-20 PE PE1998000398A patent/PE75199A1/es not_active Application Discontinuation
- 1998-05-21 AR ARP980102363A patent/AR012732A1/es not_active Application Discontinuation
- 1998-05-21 MA MA25086A patent/MA26501A1/fr unknown
- 1998-05-22 CO CO98029024A patent/CO4950515A1/es unknown
-
1999
- 1999-11-22 NO NO995711A patent/NO995711L/no not_active Application Discontinuation
- 1999-11-23 OA OA9900253A patent/OA11515A/en unknown
- 1999-12-14 BG BG104009A patent/BG104009A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
BR9809652A (pt) | 2001-09-11 |
BG104009A (en) | 2000-07-31 |
ES2201509T3 (es) | 2004-03-16 |
MA26501A1 (fr) | 2004-12-20 |
IL133036A0 (en) | 2001-03-19 |
ATE244711T1 (de) | 2003-07-15 |
CA2291111A1 (en) | 1998-11-26 |
CO4950515A1 (es) | 2000-09-01 |
DE69816290T2 (de) | 2004-05-27 |
HUP0002300A3 (en) | 2002-01-28 |
PL336942A1 (en) | 2000-07-17 |
ID22876A (id) | 1999-12-16 |
AR012732A1 (es) | 2000-11-08 |
PE75199A1 (es) | 1999-10-22 |
JP2002500645A (ja) | 2002-01-08 |
EP0983262A1 (en) | 2000-03-08 |
WO1998052942A1 (en) | 1998-11-26 |
CN1264378A (zh) | 2000-08-23 |
DZ2498A1 (fr) | 2003-01-25 |
HUP0002300A2 (hu) | 2001-06-28 |
SK159299A3 (en) | 2000-06-12 |
AU8209898A (en) | 1998-12-11 |
AP9901695A0 (en) | 1999-12-31 |
NO995711D0 (no) | 1999-11-22 |
EA199901062A1 (ru) | 2000-08-28 |
NO995711L (no) | 2000-01-19 |
DE69816290D1 (de) | 2003-08-14 |
OA11515A (en) | 2004-02-04 |
EP0983262B1 (en) | 2003-07-09 |
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