HUP0104367A2 - 8-Ciano-1-ciklopropil-7-(1S,6S-2.8-diazabiciklo[4.3.0]-nonán-8-il)-6-fluor-1,4-dihidro-4-oxo-3-kinolinkarbonsav szemi-hidrokloridja, eljárás előállítására és az ezt tartalmazó gyógyszerkészítmények - Google Patents

8-Ciano-1-ciklopropil-7-(1S,6S-2.8-diazabiciklo[4.3.0]-nonán-8-il)-6-fluor-1,4-dihidro-4-oxo-3-kinolinkarbonsav szemi-hidrokloridja, eljárás előállítására és az ezt tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0104367A2
HUP0104367A2 HU0104367A HUP0104367A HUP0104367A2 HU P0104367 A2 HUP0104367 A2 HU P0104367A2 HU 0104367 A HU0104367 A HU 0104367A HU P0104367 A HUP0104367 A HU P0104367A HU P0104367 A2 HUP0104367 A2 HU P0104367A2
Authority
HU
Hungary
Prior art keywords
nonan
diazabicyclo
cyan
cyclopropyl
dihydro
Prior art date
Application number
HU0104367A
Other languages
English (en)
Inventor
Thomas Himmler
Hubert Rast
Original Assignee
Bayer Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag. filed Critical Bayer Ag.
Publication of HUP0104367A2 publication Critical patent/HUP0104367A2/hu
Publication of HUP0104367A3 publication Critical patent/HUP0104367A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
HU0104367A 1998-11-25 1999-11-15 Semi-hydrochloride of 8-cyan-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid, process for its preparation and pharmaceutical composition thereof HUP0104367A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19854357A DE19854357A1 (de) 1998-11-25 1998-11-25 Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
PCT/EP1999/008778 WO2000031077A1 (de) 1998-11-25 1999-11-15 Semi-hydrochlorid von 8-cyan-1- cyclopropyl -7-(1s,6s-2, 8-diazabicyclo [4.3.0]nonan -8-yl)-6- fluor-1, 4-dihydro-4- oxo-3- chinolincarbonsäure

Publications (2)

Publication Number Publication Date
HUP0104367A2 true HUP0104367A2 (hu) 2002-02-28
HUP0104367A3 HUP0104367A3 (en) 2002-12-28

Family

ID=7888961

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104367A HUP0104367A3 (en) 1998-11-25 1999-11-15 Semi-hydrochloride of 8-cyan-1-cyclopropyl-7-(1s,6s-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid, process for its preparation and pharmaceutical composition thereof

Country Status (28)

Country Link
US (1) US6995170B1 (hu)
EP (1) EP1133495B1 (hu)
JP (1) JP2002530408A (hu)
KR (1) KR100740956B1 (hu)
CN (1) CN1176921C (hu)
AR (1) AR023709A1 (hu)
AT (1) ATE225790T1 (hu)
AU (1) AU759769B2 (hu)
BR (1) BR9915684A (hu)
CA (1) CA2351714C (hu)
CZ (1) CZ300058B6 (hu)
DE (2) DE19854357A1 (hu)
DK (1) DK1133495T3 (hu)
ES (1) ES2181488T3 (hu)
HK (1) HK1042704B (hu)
HU (1) HUP0104367A3 (hu)
IL (2) IL142837A0 (hu)
NO (1) NO318053B1 (hu)
NZ (1) NZ511863A (hu)
PL (1) PL196508B1 (hu)
PT (1) PT1133495E (hu)
RU (1) RU2242475C2 (hu)
SK (1) SK285561B6 (hu)
TR (1) TR200101443T2 (hu)
TW (1) TWI234565B (hu)
UA (1) UA67875C2 (hu)
WO (1) WO2000031077A1 (hu)
ZA (1) ZA013317B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE10224086A1 (de) * 2002-05-31 2003-12-11 Bayer Ag Pharmazeutische Zubereitungen zur oralen Anwendung enthaltend wirkstoffbeladene Ionentauscherharze sowie strukturviskose Gelbildner als Verdicker
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin
WO2018146194A1 (en) 2017-02-13 2018-08-16 Bayer Animal Health Gmbh Liquid composition containing pradofloxacin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
DK0882049T3 (da) * 1996-02-23 2003-03-03 Bayer Ag Eventuelt substituerede 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-quinolincarboxylsyrer og deres derivater
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure

Also Published As

Publication number Publication date
NO318053B1 (no) 2005-01-24
PL196508B1 (pl) 2008-01-31
EP1133495B1 (de) 2002-10-09
BR9915684A (pt) 2001-08-14
CN1328557A (zh) 2001-12-26
AU1271600A (en) 2000-06-13
TR200101443T2 (tr) 2001-09-21
EP1133495A1 (de) 2001-09-19
DK1133495T3 (da) 2003-02-10
SK6842001A3 (en) 2001-12-03
ZA013317B (en) 2002-06-26
JP2002530408A (ja) 2002-09-17
US6995170B1 (en) 2006-02-07
IL142837A0 (en) 2002-03-10
CZ20011753A3 (cs) 2001-09-12
KR100740956B1 (ko) 2007-07-19
NO20012532D0 (no) 2001-05-23
ES2181488T3 (es) 2003-02-16
NO20012532L (no) 2001-07-02
KR20010075694A (ko) 2001-08-09
IL142837A (en) 2006-08-01
HK1042704A1 (en) 2002-08-23
DE59903063D1 (de) 2002-11-14
HK1042704B (zh) 2005-09-09
CA2351714C (en) 2010-06-15
TWI234565B (en) 2005-06-21
UA67875C2 (uk) 2004-07-15
PL347799A1 (en) 2002-04-22
CN1176921C (zh) 2004-11-24
RU2242475C2 (ru) 2004-12-20
DE19854357A1 (de) 2000-05-31
PT1133495E (pt) 2003-02-28
CA2351714A1 (en) 2000-06-02
SK285561B6 (sk) 2007-03-01
WO2000031077A1 (de) 2000-06-02
ATE225790T1 (de) 2002-10-15
AR023709A1 (es) 2002-09-04
HUP0104367A3 (en) 2002-12-28
NZ511863A (en) 2003-05-30
CZ300058B6 (cs) 2009-01-21
AU759769B2 (en) 2003-05-01

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Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished