TR200001405T2 - 11ß pozisyonunda ikameli/katkılı yeni 19-nor steroidler hazırlama metodu-ara maddeleri. - Google Patents
11ß pozisyonunda ikameli/katkılı yeni 19-nor steroidler hazırlama metodu-ara maddeleri.Info
- Publication number
- TR200001405T2 TR200001405T2 TR2000/01405T TR200001405T TR200001405T2 TR 200001405 T2 TR200001405 T2 TR 200001405T2 TR 2000/01405 T TR2000/01405 T TR 2000/01405T TR 200001405 T TR200001405 T TR 200001405T TR 200001405 T2 TR200001405 T2 TR 200001405T2
- Authority
- TR
- Turkey
- Prior art keywords
- steroids
- substitute
- additive
- preparing new
- cycl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Bu bulus formül (I)'i havi bilesikler ile ilgili olup, burada: X bir halojen atomudur; D opsiyonel olarak ikame edilen/katkilanan ve opsiyonel olarak doymamis bir halde bulunan bir pentagonal veya heksagonal siklin geri kalanin temsil eder, R1, R2, R3, R4, X ve n de tarifnamede tarif edildigi gibidir; ve yine bu bulus hazirlama prosesini ve ara maddeleri, bunlarin ilaç olarak uygulanmasini ve de bunlari ihtiva eden farmasötik kompozisyonlari da hedeflemektedir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9714357A FR2771096B1 (fr) | 1997-11-17 | 1997-11-17 | Nouveaux 19-nor steroides, substitues en position 11beta, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200001405T2 true TR200001405T2 (tr) | 2001-05-21 |
Family
ID=9513422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/01405T TR200001405T2 (tr) | 1997-11-17 | 1998-11-16 | 11ß pozisyonunda ikameli/katkılı yeni 19-nor steroidler hazırlama metodu-ara maddeleri. |
Country Status (25)
Country | Link |
---|---|
US (2) | US6479476B1 (tr) |
EP (1) | EP1032584B1 (tr) |
JP (1) | JP4476480B2 (tr) |
KR (1) | KR20010032127A (tr) |
CN (1) | CN1286694A (tr) |
AR (1) | AR016012A1 (tr) |
AT (1) | ATE232542T1 (tr) |
AU (1) | AU754846B2 (tr) |
BR (1) | BR9814201A (tr) |
CA (1) | CA2309242A1 (tr) |
CZ (1) | CZ20001799A3 (tr) |
DE (1) | DE69811393T2 (tr) |
EA (1) | EA003133B1 (tr) |
ES (1) | ES2192341T3 (tr) |
FR (1) | FR2771096B1 (tr) |
HR (1) | HRP20000315A2 (tr) |
HU (1) | HUP0100210A3 (tr) |
ID (1) | ID24236A (tr) |
IL (1) | IL136148A0 (tr) |
NO (1) | NO20002483L (tr) |
PL (1) | PL340381A1 (tr) |
SK (1) | SK7052000A3 (tr) |
TR (1) | TR200001405T2 (tr) |
WO (1) | WO1999025725A1 (tr) |
ZA (1) | ZA9810358B (tr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2757519B1 (fr) * | 1996-12-23 | 1999-06-11 | Hoechst Marion Roussel Inc | Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant |
FR2780060B1 (fr) * | 1998-06-23 | 2000-08-04 | Hoechst Marion Roussel Inc | Nouveaux 19-nor steroides 17-halogenes, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant |
DE19929715A1 (de) * | 1999-06-24 | 2000-12-28 | Schering Ag | 11ß-langkettig-substituierte Estratriene, Verfahren zur Herstellung , pharmazeutische Präparate, die diese 11ß-langkettig-substituierten Estratriene enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln |
FR2826004B1 (fr) * | 2001-06-13 | 2008-03-28 | Aventis Pharma Sa | Procede de preparation de derives estrogenes |
FR2854403B1 (fr) * | 2003-04-29 | 2008-07-11 | Aventis Pharma Sa | Nouveau procede et intermediaires de preparation de composes 19-nor-steroides 17-halogenes |
FR2854402B1 (fr) * | 2003-04-29 | 2008-07-04 | Aventis Pharma Sa | Nouveau procede et intermediaires de preparation de composes 19-nor-steroides |
US10400006B2 (en) * | 2014-11-26 | 2019-09-03 | The Regents Of The University Of California | Estrogen receptor modulators |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4978657A (en) * | 1981-01-09 | 1990-12-18 | Roussel Uclaf | Novel 11β-substituted-19-nor-steroids |
FR2640977A2 (en) * | 1982-06-11 | 1990-06-29 | Roussel Uclaf | New position-11 substituted 19-norsteroids and their application as medicinal products. |
FR2643638B1 (fr) * | 1989-02-24 | 1991-06-14 | Roussel Uclaf | Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
-
1997
- 1997-11-17 FR FR9714357A patent/FR2771096B1/fr not_active Expired - Fee Related
-
1998
- 1998-11-12 ZA ZA9810358A patent/ZA9810358B/xx unknown
- 1998-11-16 US US09/554,783 patent/US6479476B1/en not_active Expired - Lifetime
- 1998-11-16 BR BR9814201-1A patent/BR9814201A/pt not_active IP Right Cessation
- 1998-11-16 CN CN98813160A patent/CN1286694A/zh active Pending
- 1998-11-16 EA EA200000530A patent/EA003133B1/ru not_active IP Right Cessation
- 1998-11-16 SK SK705-2000A patent/SK7052000A3/sk unknown
- 1998-11-16 EP EP98955663A patent/EP1032584B1/fr not_active Expired - Lifetime
- 1998-11-16 CA CA002309242A patent/CA2309242A1/fr not_active Abandoned
- 1998-11-16 HU HU0100210A patent/HUP0100210A3/hu unknown
- 1998-11-16 ID IDW20000928A patent/ID24236A/id unknown
- 1998-11-16 PL PL98340381A patent/PL340381A1/xx unknown
- 1998-11-16 DE DE69811393T patent/DE69811393T2/de not_active Expired - Lifetime
- 1998-11-16 CZ CZ20001799A patent/CZ20001799A3/cs unknown
- 1998-11-16 ES ES98955663T patent/ES2192341T3/es not_active Expired - Lifetime
- 1998-11-16 WO PCT/FR1998/002437 patent/WO1999025725A1/fr not_active Application Discontinuation
- 1998-11-16 AT AT98955663T patent/ATE232542T1/de not_active IP Right Cessation
- 1998-11-16 AU AU12426/99A patent/AU754846B2/en not_active Ceased
- 1998-11-16 JP JP2000521105A patent/JP4476480B2/ja not_active Expired - Fee Related
- 1998-11-16 KR KR1020007005314A patent/KR20010032127A/ko not_active Application Discontinuation
- 1998-11-16 TR TR2000/01405T patent/TR200001405T2/tr unknown
- 1998-11-16 IL IL13614898A patent/IL136148A0/xx unknown
- 1998-11-17 AR ARP980105822A patent/AR016012A1/es unknown
-
2000
- 2000-05-12 NO NO20002483A patent/NO20002483L/no not_active Application Discontinuation
- 2000-05-17 HR HR20000315A patent/HRP20000315A2/hr not_active Application Discontinuation
-
2002
- 2002-04-10 US US10/119,903 patent/US6693090B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO20002483L (no) | 2000-07-17 |
WO1999025725A1 (fr) | 1999-05-27 |
DE69811393D1 (de) | 2003-03-20 |
ZA9810358B (en) | 1999-11-12 |
CN1286694A (zh) | 2001-03-07 |
US6693090B2 (en) | 2004-02-17 |
JP4476480B2 (ja) | 2010-06-09 |
IL136148A0 (en) | 2001-05-20 |
ES2192341T3 (es) | 2003-10-01 |
SK7052000A3 (en) | 2000-12-11 |
HRP20000315A2 (en) | 2000-10-31 |
JP2001523687A (ja) | 2001-11-27 |
NO20002483D0 (no) | 2000-05-12 |
EA200000530A1 (ru) | 2000-10-30 |
ATE232542T1 (de) | 2003-02-15 |
KR20010032127A (ko) | 2001-04-16 |
FR2771096A1 (fr) | 1999-05-21 |
DE69811393T2 (de) | 2003-08-28 |
PL340381A1 (en) | 2001-01-29 |
US20030073675A1 (en) | 2003-04-17 |
BR9814201A (pt) | 2000-09-26 |
HUP0100210A1 (hu) | 2001-08-28 |
AU1242699A (en) | 1999-06-07 |
HUP0100210A3 (en) | 2001-12-28 |
FR2771096B1 (fr) | 2000-08-11 |
EA003133B1 (ru) | 2003-02-27 |
AU754846B2 (en) | 2002-11-28 |
CZ20001799A3 (cs) | 2001-11-14 |
EP1032584A1 (fr) | 2000-09-06 |
CA2309242A1 (fr) | 1999-05-27 |
AR016012A1 (es) | 2001-05-30 |
ID24236A (id) | 2000-07-13 |
US6479476B1 (en) | 2002-11-12 |
EP1032584B1 (fr) | 2003-02-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR199901578T2 (tr) | Klaritromisin form 0 kristali | |
IL123293A (en) | Piperidine derivatives, their preparation and pharmaceutical compositions containing them | |
AU6690686A (en) | Piperdine derivative and pharmaceutical composition | |
TR200001645T2 (tr) | Retinoyik asit taklidi anilürler. | |
CA2243504A1 (en) | New 19-nor-pregnene derivatives | |
BR9910971A (pt) | Composto, processos para a preparação de um composto e para produzir um efeito antibacteriano em um animal de sangue quente, uso de um composto, e, composição farmacêutica | |
DE69527400D1 (de) | Wasserlösliche camptothecin-derivate, verfahren zu deren herstellung und deren verwendung als antitumor-mittel | |
ES481729A1 (es) | Procedimiento para la preparacion de derivados de 1,2-dihi- droquinolein-2-onas. | |
DE69831690D1 (de) | Stickstoffhaltige heterocyclische verbindungen, ihre herstellung und verwendung | |
YU29300A (sh) | Katalizovane reakcije prelaznog metala bazirane na hiralnim amin oksazolinil ligandima | |
TR200001405T2 (tr) | 11ß pozisyonunda ikameli/katkılı yeni 19-nor steroidler hazırlama metodu-ara maddeleri. | |
TR200200125T2 (tr) | Yeni aminotiyazol türevleri, bunların hazırlanması ve bunları içeren farmasötik kompozisyonlar. | |
TR200000153T2 (tr) | İl-5 inhibite eden 6-azaurasil türevleri. | |
CA2107485A1 (fr) | Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
TR199802091T2 (tr) | Alfa-17 ikame/ katkilama maddesi içermeyen yeni pregnan türevleri. | |
YU51199A (sh) | Novi 4-halogeni steroidi, postupak i međuproizvodi za njihovo pripremanje, njihova primena kao medikamenata i farmaceutske kompozicije koje ih sadrže | |
EE200300124A (et) | 17alfa-fluoroalküülsteroidid, nende valmistamismeetod ja neid ühendeid sisaldavad farmatseutilised kompositsioonid | |
ES8206537A1 (es) | Procedimiento para la obtencion de nuevos derivados de la tiazolo (3,2-a) pirimidina | |
TR200100214T2 (tr) | Aerotrisin analogları, bunların hazırlanmaları ve kullanımları | |
DK0876393T3 (da) | 21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold | |
TR200003857T2 (tr) | 17 Konumunda halojenlenmiş yeni 19-nor steroitler. | |
EE200200302A (et) | Küllastumata 14,15-tsüklopropanoandrostaanid, nende valmistamise meetod ja neid ühendeid sisaldavadfarmatseutilised kompositsioonid | |
DE3166645D1 (en) | Dibenzoxazonine, dibenzoxazecine, dibenzoxaazacycloundecane derivatives and their corresponding thia- and aza derivatives, their preparation and pharmaceutical compositions | |
ATE49003T1 (de) | Pregnane derivate, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten. | |
ATE7908T1 (de) | 4-phenoxy-3-hydroxy-butyramidoximderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel. |