YU51199A - Novi 4-halogeni steroidi, postupak i međuproizvodi za njihovo pripremanje, njihova primena kao medikamenata i farmaceutske kompozicije koje ih sadrže - Google Patents

Novi 4-halogeni steroidi, postupak i međuproizvodi za njihovo pripremanje, njihova primena kao medikamenata i farmaceutske kompozicije koje ih sadrže

Info

Publication number
YU51199A
YU51199A YU51199A YU51199A YU51199A YU 51199 A YU51199 A YU 51199A YU 51199 A YU51199 A YU 51199A YU 51199 A YU51199 A YU 51199A YU 51199 A YU51199 A YU 51199A
Authority
YU
Yugoslavia
Prior art keywords
intermediates
preparation
application
pharmaceutical compositions
medicines
Prior art date
Application number
YU51199A
Other languages
English (en)
Inventor
Yasmina Bouali
Francois Nique
Jean Georges Teutsch
De Velde Patrick Van
Original Assignee
Hoechst Marion Roussel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel
Publication of YU51199A publication Critical patent/YU51199A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pronalazak se odnosi na jedinjenja formule (I) kod kojih X je halogeni atom, D predstavlja ostatak jednog petougaonog ili šestougaonog prstena, eventualno supstituisanog i eventualno zasićenog, R1, R2, R3, R4, Y i n su takvi kako su definisani u opisu. Pronalazak se takodje odnosi na postupak za njihovo pripremanje i na njihove medjuproizvode, na njihovu primenu kao medikamenata i na farmaceutske kompozicije koje ih sadrže.[The invention concerns compounds of formula (I) in which X is a halogen atom; D represents the residue of a pentagonal or hexagonal cycle, optionally substituted and optionally unsaturated; R1, R2, R3, R4, Y and n are such as defined in the description. The invention also concerns the preparation method and intermediates thereof, their application as medicine and the pharmaceutical compositions containing them.
YU51199A 1997-04-09 1998-04-08 Novi 4-halogeni steroidi, postupak i međuproizvodi za njihovo pripremanje, njihova primena kao medikamenata i farmaceutske kompozicije koje ih sadrže YU51199A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9704321A FR2761992B1 (fr) 1997-04-09 1997-04-09 Nouveaux steroides 4-halogenes, leur procede et intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
YU51199A true YU51199A (sh) 2002-09-19

Family

ID=9505672

Family Applications (1)

Application Number Title Priority Date Filing Date
YU51199A YU51199A (sh) 1997-04-09 1998-04-08 Novi 4-halogeni steroidi, postupak i međuproizvodi za njihovo pripremanje, njihova primena kao medikamenata i farmaceutske kompozicije koje ih sadrže

Country Status (31)

Country Link
US (5) US6239121B1 (sh)
EP (1) EP0973793B1 (sh)
JP (1) JP4347420B2 (sh)
KR (1) KR20010006149A (sh)
CN (1) CN1259956A (sh)
AP (1) AP1137A (sh)
AR (1) AR012377A1 (sh)
AT (1) ATE220408T1 (sh)
AU (1) AU750030B2 (sh)
BR (1) BR9809578A (sh)
CA (1) CA2285679A1 (sh)
DE (1) DE69806473T2 (sh)
DK (1) DK0973793T3 (sh)
EA (1) EA002116B1 (sh)
ES (1) ES2178208T3 (sh)
FR (1) FR2761992B1 (sh)
HR (1) HRP980196B1 (sh)
HU (1) HUP0002457A3 (sh)
ID (1) ID22930A (sh)
IL (1) IL132202A (sh)
NO (1) NO315049B1 (sh)
NZ (1) NZ337947A (sh)
PL (1) PL190629B1 (sh)
PT (1) PT973793E (sh)
SK (1) SK284480B6 (sh)
TR (1) TR199902507T2 (sh)
TW (1) TW505621B (sh)
UA (1) UA57073C2 (sh)
WO (1) WO1998045316A1 (sh)
YU (1) YU51199A (sh)
ZA (1) ZA983046B (sh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757519B1 (fr) * 1996-12-23 1999-06-11 Hoechst Marion Roussel Inc Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant
FR2780060B1 (fr) * 1998-06-23 2000-08-04 Hoechst Marion Roussel Inc Nouveaux 19-nor steroides 17-halogenes, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant
FR2826004B1 (fr) * 2001-06-13 2008-03-28 Aventis Pharma Sa Procede de preparation de derives estrogenes
FR2854402B1 (fr) * 2003-04-29 2008-07-04 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de composes 19-nor-steroides
PL2125827T3 (pl) * 2006-12-29 2011-04-29 Hoffmann La Roche Pochodne azaspiro
US20120046461A1 (en) * 2009-01-23 2012-02-23 Northeastern University Steroidal anti-hormone hybrids
FR2942409B1 (fr) * 2009-02-20 2013-07-26 Natacha Voillot Composition pharmaceutique pour la prevention des avortements a repetition.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640977A2 (en) * 1982-06-11 1990-06-29 Roussel Uclaf New position-11 substituted 19-norsteroids and their application as medicinal products.
US4676932A (en) * 1984-04-09 1987-06-30 The University Of New Mexico Synthesis of 1-haloestradiols
US4859585A (en) * 1986-04-17 1989-08-22 Trustees Of Tufts College In-vitro methods for identifying compositions which are agonists and antagonists of estrogens

Also Published As

Publication number Publication date
US6462211B1 (en) 2002-10-08
TR199902507T2 (xx) 2000-07-21
AU750030B2 (en) 2002-07-11
NZ337947A (en) 2001-04-27
FR2761992A1 (fr) 1998-10-16
ATE220408T1 (de) 2002-07-15
KR20010006149A (ko) 2001-01-26
HRP980196B1 (en) 2003-08-31
IL132202A0 (en) 2001-03-19
EA002116B1 (ru) 2001-12-24
AU7339698A (en) 1998-10-30
EP0973793A1 (fr) 2000-01-26
US6472382B2 (en) 2002-10-29
HUP0002457A1 (hu) 2001-02-28
PT973793E (pt) 2002-11-29
NO994908D0 (no) 1999-10-08
UA57073C2 (uk) 2003-06-16
IL132202A (en) 2004-02-19
EA199900909A1 (ru) 2000-04-24
SK136299A3 (en) 2000-05-16
CA2285679A1 (fr) 1998-10-15
SK284480B6 (sk) 2005-04-01
DE69806473T2 (de) 2003-02-13
DE69806473D1 (de) 2002-08-14
US6239121B1 (en) 2001-05-29
PL336116A1 (en) 2000-06-05
HRP980196A2 (en) 1998-12-31
JP4347420B2 (ja) 2009-10-21
ID22930A (id) 1999-12-16
NO994908L (no) 1999-12-07
BR9809578A (pt) 2000-07-04
EP0973793B1 (fr) 2002-07-10
US20010039268A1 (en) 2001-11-08
AR012377A1 (es) 2000-10-18
AP9901656A0 (en) 1999-09-30
US20020040135A1 (en) 2002-04-04
TW505621B (en) 2002-10-11
JP2001518891A (ja) 2001-10-16
PL190629B1 (pl) 2005-12-30
US20010005756A1 (en) 2001-06-28
ES2178208T3 (es) 2002-12-16
FR2761992B1 (fr) 1999-06-11
DK0973793T3 (da) 2002-10-28
ZA983046B (en) 1999-04-09
AP1137A (en) 2003-01-12
NO315049B1 (no) 2003-06-30
WO1998045316A1 (fr) 1998-10-15
US20010008941A1 (en) 2001-07-19
CN1259956A (zh) 2000-07-12
US6399766B2 (en) 2002-06-04
HUP0002457A3 (en) 2002-07-29

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