DK0876393T3 - 21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold - Google Patents

21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold

Info

Publication number
DK0876393T3
DK0876393T3 DK96943204T DK96943204T DK0876393T3 DK 0876393 T3 DK0876393 T3 DK 0876393T3 DK 96943204 T DK96943204 T DK 96943204T DK 96943204 T DK96943204 T DK 96943204T DK 0876393 T3 DK0876393 T3 DK 0876393T3
Authority
DK
Denmark
Prior art keywords
pct
pregnant
thio
oxo
tetrahydrofuran
Prior art date
Application number
DK96943204T
Other languages
English (en)
Inventor
Keith Biggadike
Rosanne Mary Farrell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9526630.0A external-priority patent/GB9526630D0/en
Priority claimed from GBGB9613036.4A external-priority patent/GB9613036D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK0876393T3 publication Critical patent/DK0876393T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
DK96943204T 1995-12-29 1996-12-19 21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold DK0876393T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9526630.0A GB9526630D0 (en) 1995-12-29 1995-12-29 Compounds
GBGB9613036.4A GB9613036D0 (en) 1996-06-21 1996-06-21 Compounds
PCT/GB1996/003153 WO1997024367A1 (en) 1995-12-29 1996-12-19 21-(2-oxo-tetrahydrofuran)-thio pregnane derivatives, a process for their production and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DK0876393T3 true DK0876393T3 (da) 2000-11-06

Family

ID=26308399

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96943204T DK0876393T3 (da) 1995-12-29 1996-12-19 21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold

Country Status (12)

Country Link
US (1) US6013244A (da)
EP (1) EP0876393B1 (da)
JP (1) JP2947945B2 (da)
AT (1) ATE194357T1 (da)
AU (1) AU1200097A (da)
DE (1) DE69609201T2 (da)
DK (1) DK0876393T3 (da)
ES (1) ES2150151T3 (da)
GR (1) GR3034563T3 (da)
PT (1) PT876393E (da)
SI (1) SI0876393T1 (da)
WO (1) WO1997024367A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2215310T3 (es) * 1997-06-30 2004-10-01 Glaxo Group Limited Procedimiento para identificar compuestos que tienen una actividad sistemica reducida.
WO2004028545A1 (en) * 2002-09-25 2004-04-08 Astrazeneca Ab A COMBINATION OF A LONG-ACTING β2-AGONIST AND A GLUCOCORTICOSTEROID IN THE TREATMENT OF FIBROTIC DISEASES
WO2008124145A1 (en) * 2007-04-05 2008-10-16 Government Of The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Steroid compounds, compositions, and methods of treatment
EP2235035A2 (en) * 2007-12-21 2010-10-06 Schering Corporation C-21 thioethers as glucocorticoid receptor agonists
AR077101A1 (es) 2009-06-16 2011-08-03 Schering Corp Esteroides de heteroarilo (3,2-c), como agonistas de receptor glucocorticoide, composiciones y usos de los mismos
WO2024125639A1 (zh) * 2022-12-16 2024-06-20 津药生物科技（天津）有限公司 新型糖皮质激素、其制备方法及用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420120A (en) * 1993-12-17 1995-05-30 Alcon Laboratories, Inc. Anti-inflammatory glucocorticoid compounds for topical ophthalmic use

Also Published As

Publication number Publication date
DE69609201D1 (de) 2000-08-10
PT876393E (pt) 2000-12-29
DE69609201T2 (de) 2001-03-01
JPH11501676A (ja) 1999-02-09
EP0876393A1 (en) 1998-11-11
AU1200097A (en) 1997-07-28
SI0876393T1 (en) 2000-12-31
JP2947945B2 (ja) 1999-09-13
GR3034563T3 (en) 2001-01-31
ATE194357T1 (de) 2000-07-15
ES2150151T3 (es) 2000-11-16
WO1997024367A1 (en) 1997-07-10
EP0876393B1 (en) 2000-07-05
US6013244A (en) 2000-01-11

Similar Documents

Publication Publication Date Title
TR199900920T2 (xx) Nafthiridin t�revleri.
MX9805181A (es) Derivados de lactona a partir de derivados de 17.beta- carboxi, carbotio y amida androstano.
FI113644B (fi) Menetelmä terapeuttisesti aktiivisten N-substituoitujen 3- atsabisykloalkaanijohdannaisten valmistamiseksi
ATE208772T1 (de) Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung
DE69523622T2 (de) Diastereomerenreine 3-oxo und 3-thioxo-4-aza-androstanderivate und ihre verwendung als antiandrogene
DE69632193D1 (de) Cyclooxygenaseinhibitor und salze von amidinderivaten, verfahren zu deren herstellung, deren verwendung als arzneiwirkstoffe sowie diese salze enthaltende arzneimittel
DK0614362T3 (da) Farmaceutiske præparater på basis af ebastin og dermed analoge forbindelser
FI973221A0 (fi) 1-aryyli-2-asyyliammo-etaaniyhdisteitä ja niiden käyttö neurokiniiniantagonisteina, erityisesti neurokiniini 1 antagonisteina
DK0876393T3 (da) 21-(2-oxo-tetrahydrofuran)-thio-pregnanderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indehold
FI962323A0 (fi) N-substituoidut atsabisykloheptaanijohdannaiset, kuten esim. neuroleptit
DK0559690T3 (da) 8-en-19,11Beta-broholdige steroider, deres fremstilling og farmaceutiske præparater, som indeholder dem
ATE212996T1 (de) Anthracyclin-derivate
MX9303605A (es) Derivados de azabicicloheptano n-substituidas, su obtencion y uso.
MX9303574A (es) Compuestos heterociclicos que son inhibidores de la enzima aromatasa, proceso para su preparacion ycomposiciones farmaceuticas que los contienen.
ATE195529T1 (de) 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung
AP1579A (en) Novel 17-Halogenated 19-nor steroids, method and intermediates for preparing same, use as medicines and pharmaceutical compositions containing same.
NO305519B1 (no) Benzo[f]kinoksalindionderivater og legemidler inneholdende disse
DE60000415T2 (de) 11.beta.-substituierte steroide, verfahren zu ihrer herstellung sowie zwischenprodukte davon, ihre verwendung als medikamente und pharmazeutische zusammensetzungen davon