ATE195529T1 - 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung - Google Patents

17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung

Info

Publication number
ATE195529T1
ATE195529T1 AT96942491T AT96942491T ATE195529T1 AT E195529 T1 ATE195529 T1 AT E195529T1 AT 96942491 T AT96942491 T AT 96942491T AT 96942491 T AT96942491 T AT 96942491T AT E195529 T1 ATE195529 T1 AT E195529T1
Authority
AT
Austria
Prior art keywords
17beta
thio
derivatives
lactone
oxo
Prior art date
Application number
AT96942491T
Other languages
English (en)
Inventor
Keith Biggadike
Panayiotis Alexandro Procopiou
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9526677.1A external-priority patent/GB9526677D0/en
Priority claimed from GBGB9613120.6A external-priority patent/GB9613120D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE195529T1 publication Critical patent/ATE195529T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96942491T 1995-12-29 1996-12-19 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung ATE195529T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9526677.1A GB9526677D0 (en) 1995-12-29 1995-12-29 Compounds
GBGB9613120.6A GB9613120D0 (en) 1996-06-21 1996-06-21 Compounds
PCT/GB1996/003138 WO1997024368A1 (en) 1995-12-29 1996-12-19 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio-androstane derivatives (17beta-(gamma-butyric acid lactone)-thio derivatives) for the treatment of inflammation and pharmaceutical compositions and a process for the production thereof

Publications (1)

Publication Number Publication Date
ATE195529T1 true ATE195529T1 (de) 2000-09-15

Family

ID=26308405

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96942491T ATE195529T1 (de) 1995-12-29 1996-12-19 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung

Country Status (11)

Country Link
US (1) US6114318A (de)
EP (1) EP0883628B1 (de)
JP (1) JP2951000B2 (de)
AT (1) ATE195529T1 (de)
AU (1) AU1185197A (de)
DE (1) DE69609870T2 (de)
DK (1) DK0883628T3 (de)
ES (1) ES2150149T3 (de)
GR (1) GR3034439T3 (de)
PT (1) PT883628E (de)
WO (1) WO1997024368A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001467A2 (en) * 1997-06-30 1999-01-14 Glaxo Group Limited Therapeutically active compounds with low systemic activity due to reduce half life
JP3847065B2 (ja) * 2000-08-21 2006-11-15 松下電器産業株式会社 地点登録装置
ITRM20020458A1 (it) * 2002-09-13 2004-03-14 Ambiotec S A S Di Ammendola Sergio Procedimento per la separazione preparativa degli epimeri di steroidi.
TW201111392A (en) 2009-06-16 2011-04-01 Schering Corp Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481144A (en) * 1984-02-03 1984-11-06 E. R. Squibb & Sons, Inc. 17-Substituted thia-17-alkyl(or alkenyl or alkynyl)androstenes
US4529548A (en) * 1984-05-07 1985-07-16 E. R. Squibb & Sons, Inc. 17β-(substituted thio)androstenes
PL309402A1 (en) * 1992-12-24 1995-10-02 Rhone Poulenc Rorer Ltd Novel steroides

Also Published As

Publication number Publication date
JP2951000B2 (ja) 1999-09-20
ES2150149T3 (es) 2000-11-16
GR3034439T3 (en) 2000-12-29
DE69609870D1 (de) 2000-09-21
US6114318A (en) 2000-09-05
DK0883628T3 (da) 2000-11-06
WO1997024368A1 (en) 1997-07-10
DE69609870T2 (de) 2001-01-25
AU1185197A (en) 1997-07-28
EP0883628B1 (de) 2000-08-16
EP0883628A1 (de) 1998-12-16
PT883628E (pt) 2001-01-31
JPH11501674A (ja) 1999-02-09

Similar Documents

Publication Publication Date Title
DE69429078T2 (de) Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung
ATE175201T1 (de) Mono-n-substituierte 1,4,7,10- tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
MX9805181A (es) Derivados de lactona a partir de derivados de 17.beta- carboxi, carbotio y amida androstano.
ATE220681T1 (de) Wasserlösliche camptothecin-derivate, verfahren zu deren herstellung und deren verwendung als antitumor-mittel
DE69632193D1 (de) Cyclooxygenaseinhibitor und salze von amidinderivaten, verfahren zu deren herstellung, deren verwendung als arzneiwirkstoffe sowie diese salze enthaltende arzneimittel
ATE154031T1 (de) 8-en-19, 11 beta-überbrückte steroide, deren herstellung und diese enthaltende pharmazeutische präparate
ATE195529T1 (de) 17beta-(2-oxo-tetrahydrofuran-4-yl)-thio- androstane derivate (17beta-(gamma-buttersäure- lacton)-thio derivate) zur behandlung von entzündungen, pharmazeutische präparate davon und ein verfahren zu ihrer herstellung
ATE194357T1 (de) 21-(2-oxo-tetrahydrofuran)-thio pregnan derivative, ein verfahren zu ihrer herstellung und pharmazeutische präparate davon
ATE215525T1 (de) Stabile derivate von ubiquinol, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung
ATE192438T1 (de) Bis-2-aminopyridine, verfahren zu ihrer herstelung und ihre verwendung zur bekämpfung von parasitosen
DE59507531D1 (de) Cyclohexanon-derivate, verfahren zu deren herstellung und zwischenprodukte des verfahrens
DE59607683D1 (de) Neue borneolderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
ATE200277T1 (de) Substituierte phenylamidine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE59602622D1 (de) Neue pyridin- bzw. pyridazinderivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE59402079D1 (de) Benzo[f]chinoxalindionderivative, deren herstellung und verwendung in arzneimitteln
ATE141593T1 (de) Leukotrien-b 4?-derivative, verfahren zu ihrer herstellung und arzneimittel
DE69215511T2 (de) Gem-diphosphonsäure-nitrosocarbamoylderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zubereitungen
NO952926D0 (no) Fremgangsmåte for fremstilling av C-substituerte dietylentriaminer

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee