TR200001000T2 - Kapsüllerin ve farmasötik formülasyonların muamele edilmesine yönelik metodlar. - Google Patents
Kapsüllerin ve farmasötik formülasyonların muamele edilmesine yönelik metodlar.Info
- Publication number
- TR200001000T2 TR200001000T2 TR2000/01000T TR200001000T TR200001000T2 TR 200001000 T2 TR200001000 T2 TR 200001000T2 TR 2000/01000 T TR2000/01000 T TR 2000/01000T TR 200001000 T TR200001000 T TR 200001000T TR 200001000 T2 TR200001000 T2 TR 200001000T2
- Authority
- TR
- Turkey
- Prior art keywords
- methods
- pharmaceutical formulations
- capsules
- treating capsules
- treating
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000000428 dust Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 229920003023 plastic Polymers 0.000 abstract 1
- 239000004033 plastic Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4883—Capsule finishing, e.g. dyeing, aromatising, polishing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0203—Solvent extraction of solids with a supercritical fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/02—Equipment for testing the apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
Kuru, toz halindeki bir farmasötik formülasyonun depolanmasi için kullanilan jelatin, selüloz veya plastik kapsüllerde mevcut olan arzu edilmeyen maddeler süperkritik akiskan maddeler ile ekstraksiyona tabi tutulur. Metod, ayni zamanda, ilaç tozundan arzu edilmeyen maddenin bertaraf edilmesi için de kullanilir. Teneffüsten sonra kapsüllerde tutulan toz miktari asgari bir düzeye iner.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6209997P | 1997-10-14 | 1997-10-14 | |
US09/157,267 US6228394B1 (en) | 1997-10-14 | 1998-09-21 | Supercritical fluid extraction of mould lubricant from hard shell capsules |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200001000T2 true TR200001000T2 (tr) | 2000-11-21 |
Family
ID=26741866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/01000T TR200001000T2 (tr) | 1997-10-14 | 1998-10-05 | Kapsüllerin ve farmasötik formülasyonların muamele edilmesine yönelik metodlar. |
Country Status (23)
Country | Link |
---|---|
US (1) | US6228394B1 (tr) |
EP (1) | EP1024794B1 (tr) |
JP (1) | JP2001519380A (tr) |
KR (1) | KR20010031097A (tr) |
CN (1) | CN1306420A (tr) |
AT (1) | ATE350019T1 (tr) |
AU (1) | AU753076B2 (tr) |
BG (1) | BG65169B1 (tr) |
BR (1) | BR9814818A (tr) |
CA (1) | CA2302276C (tr) |
CY (1) | CY1106033T1 (tr) |
CZ (1) | CZ299101B6 (tr) |
DE (1) | DE69836822T2 (tr) |
DK (1) | DK1024794T3 (tr) |
EE (1) | EE200000292A (tr) |
ES (1) | ES2281141T3 (tr) |
HU (1) | HUP0003990A3 (tr) |
IL (1) | IL134731A0 (tr) |
NZ (1) | NZ504394A (tr) |
PL (1) | PL195462B1 (tr) |
PT (1) | PT1024794E (tr) |
TR (1) | TR200001000T2 (tr) |
WO (1) | WO1999018939A1 (tr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6294194B1 (en) | 1997-10-14 | 2001-09-25 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for extraction and reaction using supercritical fluids |
GB9804379D0 (en) * | 1998-03-02 | 1998-04-22 | Bradford Particle Design Ltd | Method of particle formation |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
HU226982B1 (en) * | 2000-10-12 | 2010-04-28 | Boehringer Ingelheim Pharma | Novel tiotropium-containing inhalation powder, process for its preperation and its use |
US6544282B1 (en) | 2001-02-21 | 2003-04-08 | Radiant Medical, Inc. | Inhibition of platelet activation, aggregation and/or adhesion by hypothermia |
US20030070679A1 (en) * | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
DE10126924A1 (de) * | 2001-06-01 | 2002-12-05 | Boehringer Ingelheim Pharma | Inhalationskapseln |
ES2300568T3 (es) | 2002-03-20 | 2008-06-16 | Mannkind Corporation | Aparato de inhalacion. |
US20030181749A1 (en) * | 2002-03-21 | 2003-09-25 | Kunzler Jay F. | Supercritical fluid extraction of vitreoretinal silicone tamponades |
JP2005523951A (ja) * | 2002-04-23 | 2005-08-11 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | カルボマー中の残留有機溶媒の低減方法 |
JP2005530765A (ja) * | 2002-05-07 | 2005-10-13 | ネクター セラピューティクス | 乾燥粉末吸入器のためのカプセル及びそれを製造及び使用する方法 |
US7763280B2 (en) * | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
WO2005018410A1 (de) * | 2003-07-30 | 2005-03-03 | BSH Bosch und Siemens Hausgeräte GmbH | Verfahren zum betreiben eines gerätes mit wenigstens einem teilprogrammschritt 'trocknen' |
MX2007001903A (es) | 2004-08-20 | 2007-08-02 | Mannkind Corp | Catalisis de sintesis de dicetopiperazina. |
DK1791542T3 (en) | 2004-08-23 | 2015-06-15 | Mannkind Corp | Diketopiperazinsalte for pharmaceutical delivery |
DE102004060479A1 (de) * | 2004-12-16 | 2006-06-29 | Schaeffler Kg | Verfahren und Vorrichtung zum Schmieren und Kühlen eines hochbelasteten Lagers |
JP5339328B2 (ja) * | 2005-07-21 | 2013-11-13 | 独立行政法人物質・材料研究機構 | 薬物吸入デバイス |
CA2621806C (en) | 2005-09-14 | 2016-08-02 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents |
CN101389348A (zh) | 2006-02-22 | 2009-03-18 | 曼金德公司 | 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法 |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
EP3281663B8 (en) | 2008-06-13 | 2022-09-21 | MannKind Corporation | Breath powered dry powder inhaler for drug delivery |
ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
WO2010105094A1 (en) | 2009-03-11 | 2010-09-16 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
ES2943333T3 (es) | 2009-06-12 | 2023-06-12 | Mannkind Corp | Micropartículas de dicetopiperazina con superficies específicas definidas |
EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
CA2801936C (en) | 2010-06-21 | 2021-06-01 | Mannkind Corporation | Dry powder drug delivery system and methods |
CN105667994B (zh) | 2011-04-01 | 2018-04-06 | 曼金德公司 | 用于药物药盒的泡罩包装 |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
KR20140095483A (ko) | 2011-10-24 | 2014-08-01 | 맨카인드 코포레이션 | 통증을 치료하기 위한 방법 및 조성물 |
CN104619369B (zh) | 2012-07-12 | 2018-01-30 | 曼金德公司 | 干粉药物输送系统和方法 |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
US10421729B2 (en) | 2013-03-15 | 2019-09-24 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
CN114848614A (zh) | 2013-07-18 | 2022-08-05 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
CN108451920A (zh) * | 2018-03-14 | 2018-08-28 | 绍兴康可胶囊有限公司 | 一种吸雾式胶囊及其制备方法 |
CN109289249A (zh) * | 2018-12-08 | 2019-02-01 | 内蒙合成化工研究所 | 一种高能推进剂中增塑剂和安定剂的回收方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61155265A (ja) | 1984-12-26 | 1986-07-14 | 住友重機械工業株式会社 | 超臨界流体により成形体中のバインダ−を除去する方法 |
JPH0363232A (ja) | 1989-07-10 | 1991-03-19 | Syntex Usa Inc | 溶剤抽出方法 |
ATE122248T1 (de) | 1989-07-31 | 1995-05-15 | Ciba Geigy Ag | Extraktion organischer lösungsmittel aus geformten stoffen durch überkritische fluide und gase, nahe am kritischen punkt. |
US5254335A (en) * | 1990-10-10 | 1993-10-19 | Clairol Incorporated | Hair conditioning compounds containing reactive nonionic surfactants and isothiuronium compounds and method of use |
US5198115A (en) * | 1991-07-09 | 1993-03-30 | Analytical Bio-Chemistry Laboratories, Inc. | Integrated instrument for supercritical fluid sample extraction, sample separation and concentration |
US5481058A (en) | 1994-01-07 | 1996-01-02 | Minnesota Mining And Manufacturing Company | Supercritical fluid extraction involving hydrofluoroalkanes |
US5641510A (en) | 1994-07-01 | 1997-06-24 | Genentech, Inc. | Method for treating capsules used for drug storage |
-
1998
- 1998-09-21 US US09/157,267 patent/US6228394B1/en not_active Expired - Lifetime
- 1998-10-05 JP JP2000515575A patent/JP2001519380A/ja active Pending
- 1998-10-05 ES ES98952043T patent/ES2281141T3/es not_active Expired - Lifetime
- 1998-10-05 CZ CZ20001365A patent/CZ299101B6/cs not_active IP Right Cessation
- 1998-10-05 EP EP98952043A patent/EP1024794B1/en not_active Expired - Lifetime
- 1998-10-05 KR KR1020007003963A patent/KR20010031097A/ko active Search and Examination
- 1998-10-05 TR TR2000/01000T patent/TR200001000T2/tr unknown
- 1998-10-05 DK DK98952043T patent/DK1024794T3/da active
- 1998-10-05 BR BR9814818-4A patent/BR9814818A/pt not_active IP Right Cessation
- 1998-10-05 DE DE69836822T patent/DE69836822T2/de not_active Expired - Lifetime
- 1998-10-05 CA CA002302276A patent/CA2302276C/en not_active Expired - Fee Related
- 1998-10-05 PL PL98342650A patent/PL195462B1/pl not_active IP Right Cessation
- 1998-10-05 AT AT98952043T patent/ATE350019T1/de not_active IP Right Cessation
- 1998-10-05 WO PCT/US1998/020815 patent/WO1999018939A1/en active IP Right Grant
- 1998-10-05 NZ NZ504394A patent/NZ504394A/xx unknown
- 1998-10-05 PT PT98952043T patent/PT1024794E/pt unknown
- 1998-10-05 HU HU0003990A patent/HUP0003990A3/hu unknown
- 1998-10-05 AU AU97838/98A patent/AU753076B2/en not_active Ceased
- 1998-10-05 IL IL13473198A patent/IL134731A0/xx not_active IP Right Cessation
- 1998-10-05 CN CN98810156A patent/CN1306420A/zh active Pending
- 1998-10-05 EE EEP200000292A patent/EE200000292A/xx unknown
-
2000
- 2000-04-07 BG BG104317A patent/BG65169B1/bg active Active
-
2007
- 2007-02-20 CY CY20071100224T patent/CY1106033T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU9783898A (en) | 1999-05-03 |
AU753076B2 (en) | 2002-10-10 |
CA2302276A1 (en) | 1999-04-22 |
CZ299101B6 (cs) | 2008-04-23 |
PL342650A1 (en) | 2001-06-18 |
KR20010031097A (ko) | 2001-04-16 |
IL134731A0 (en) | 2001-04-30 |
HUP0003990A3 (en) | 2001-04-28 |
BG104317A (en) | 2000-12-29 |
EP1024794A1 (en) | 2000-08-09 |
PL195462B1 (pl) | 2007-09-28 |
WO1999018939A1 (en) | 1999-04-22 |
HUP0003990A2 (en) | 2001-03-28 |
WO1999018939A9 (en) | 1999-06-03 |
BR9814818A (pt) | 2000-10-03 |
DE69836822T2 (de) | 2007-04-26 |
PT1024794E (pt) | 2007-02-28 |
ES2281141T3 (es) | 2007-09-16 |
NZ504394A (en) | 2002-12-20 |
CN1306420A (zh) | 2001-08-01 |
BG65169B1 (bg) | 2007-05-31 |
US6228394B1 (en) | 2001-05-08 |
EE200000292A (et) | 2001-08-15 |
CZ20001365A3 (cs) | 2000-09-13 |
DE69836822D1 (de) | 2007-02-15 |
JP2001519380A (ja) | 2001-10-23 |
CA2302276C (en) | 2008-02-05 |
CY1106033T1 (el) | 2011-04-06 |
DK1024794T3 (da) | 2007-04-10 |
ATE350019T1 (de) | 2007-01-15 |
EP1024794B1 (en) | 2007-01-03 |
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