TR200100144T2 - Farmasötik aerosol formülasyonu - Google Patents
Farmasötik aerosol formülasyonuInfo
- Publication number
- TR200100144T2 TR200100144T2 TR2001/00144T TR200100144T TR200100144T2 TR 200100144 T2 TR200100144 T2 TR 200100144T2 TR 2001/00144 T TR2001/00144 T TR 2001/00144T TR 200100144 T TR200100144 T TR 200100144T TR 200100144 T2 TR200100144 T2 TR 200100144T2
- Authority
- TR
- Turkey
- Prior art keywords
- pharmaceutical aerosol
- aerosol formulation
- therapeutic agent
- relates
- formulations
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000008249 pharmaceutical aerosol Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 3
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Bu bulus, asagidaki kisimlari içeren yeni farmasötik aerosol formülasyonlarina ve bu formülasyonlarin hazirlanmasi için bir isleme iliskindir: (A) en azindan bir kaplama ilaç yardimci maddesi ve en azindan bir sürfaktan ile kaplanmis parçaciklar biçiminde bir terapötik madde, (B) özellikle soluma yolu ile terapötik maddelerin tatbikati için bir sivilastirilmis sevk gazi. Bulus ayni zamanda bu formülasyonlarda kullanim için müsait yeni parçaciklara da iliskindir.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9808152.4A GB9808152D0 (en) | 1998-04-18 | 1998-04-18 | Pharmaceutical aerosol formulation |
GBGB9814709.3A GB9814709D0 (en) | 1998-07-08 | 1998-07-08 | Pharmaceutical aerosol formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200100144T2 true TR200100144T2 (tr) | 2001-06-21 |
Family
ID=26313483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/00144T TR200100144T2 (tr) | 1998-04-18 | 1999-04-15 | Farmasötik aerosol formülasyonu |
Country Status (30)
Country | Link |
---|---|
US (1) | US7521042B2 (tr) |
EP (1) | EP1073417B1 (tr) |
JP (1) | JP2002512183A (tr) |
KR (1) | KR20010042816A (tr) |
CN (1) | CN1145478C (tr) |
AP (1) | AP2000001961A0 (tr) |
AR (1) | AR018183A1 (tr) |
AT (1) | ATE228823T1 (tr) |
AU (1) | AU755066B2 (tr) |
BR (1) | BR9909736A (tr) |
CA (1) | CA2328882A1 (tr) |
CO (1) | CO5021210A1 (tr) |
DE (1) | DE69904312T2 (tr) |
DK (1) | DK1073417T3 (tr) |
EA (1) | EA200000956A1 (tr) |
EE (1) | EE200000608A (tr) |
ES (1) | ES2189410T3 (tr) |
HR (1) | HRP20000689A2 (tr) |
HU (1) | HUP0101608A2 (tr) |
ID (1) | ID27887A (tr) |
IL (1) | IL139087A0 (tr) |
IS (1) | IS5665A (tr) |
MA (1) | MA26621A1 (tr) |
NO (1) | NO20005218L (tr) |
NZ (1) | NZ507619A (tr) |
PE (1) | PE20000433A1 (tr) |
PL (1) | PL343491A1 (tr) |
PT (1) | PT1073417E (tr) |
TR (1) | TR200100144T2 (tr) |
WO (1) | WO1999053901A1 (tr) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9616237D0 (en) | 1996-08-01 | 1996-09-11 | Norton Healthcare Ltd | Aerosol formulations |
US6119853A (en) * | 1998-12-18 | 2000-09-19 | Glaxo Wellcome Inc. | Method and package for storing a pressurized container containing a drug |
US6390291B1 (en) | 1998-12-18 | 2002-05-21 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
WO2000061108A1 (en) * | 1999-04-14 | 2000-10-19 | Glaxo Group Limited | Pharmaceutical aerosol formulation |
AU2002222118A1 (en) † | 2000-11-30 | 2002-06-11 | Vectura Limited | Pharmaceutical compositions for inhalation |
DK1337240T4 (en) | 2000-11-30 | 2015-01-05 | Vectura Ltd | A process for the preparation of particles for use in a pharmaceutical composition |
EP1581639A4 (en) * | 2002-12-17 | 2006-03-08 | Medimmune Vaccines Inc | HIGH PRESSURE PULVISATION OF BIOACTIVE MATERIALS |
ITMI20022674A1 (it) * | 2002-12-18 | 2004-06-19 | Chiesi Farma Spa | Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione. |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
US6962006B2 (en) * | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
PE20040950A1 (es) | 2003-02-14 | 2005-01-01 | Theravance Inc | DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS |
WO2004103348A2 (en) * | 2003-05-19 | 2004-12-02 | Baxter International Inc. | Solid particles comprising an anticonvulsant or an immunosuppressive coated with one or more surface modifiers |
TWI341836B (en) | 2004-03-11 | 2011-05-11 | Theravance Inc | Biphenyl compounds useful as muscarinic receptor antagonists |
EP1833822A2 (en) | 2004-08-16 | 2007-09-19 | Theravance, Inc. | Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
JP5156397B2 (ja) * | 2005-02-10 | 2013-03-06 | グラクソ グループ リミテッド | 予備分級技術を用いて乳糖を製造する方法及びその乳糖から形成させた医薬製剤 |
CA2653384C (en) | 2006-06-30 | 2017-03-14 | Iceutica Pty Ltd | Methods for the preparation of biologically active compounds in nanoparticulate form |
US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8414526B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids |
US20080175887A1 (en) | 2006-11-20 | 2008-07-24 | Lixiao Wang | Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs |
US9737640B2 (en) | 2006-11-20 | 2017-08-22 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8414525B2 (en) * | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8998846B2 (en) | 2006-11-20 | 2015-04-07 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US8425459B2 (en) | 2006-11-20 | 2013-04-23 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent |
US9700704B2 (en) | 2006-11-20 | 2017-07-11 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US20080276935A1 (en) | 2006-11-20 | 2008-11-13 | Lixiao Wang | Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs |
WO2010024898A2 (en) | 2008-08-29 | 2010-03-04 | Lutonix, Inc. | Methods and apparatuses for coating balloon catheters |
CN102405044A (zh) | 2009-02-06 | 2012-04-04 | 南加利福尼亚大学 | 含有单萜的治疗组合物 |
EP3578169B1 (en) | 2009-02-26 | 2024-06-26 | Glaxo Group Limited | Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol |
CA2765621C (en) | 2009-07-15 | 2018-02-13 | Theravance, Inc. | Crystalline freebase forms of a biphenyl compound |
GB0921075D0 (en) | 2009-12-01 | 2010-01-13 | Glaxo Group Ltd | Novel combination of the therapeutic agents |
BR112012022209A2 (pt) | 2010-03-03 | 2017-06-06 | Neonc Tech Inc | composições farmacêuticas compreendendo monoterpenos |
KR101445957B1 (ko) * | 2010-06-08 | 2014-09-29 | 각코우호우징 고베가쿠인 | 코팅 입자 및 코팅 입자의 제조 방법 |
US20160038600A1 (en) | 2012-08-03 | 2016-02-11 | Neonc Technologies Inc. | Pharmaceutical compositions comprising poh derivatives |
ES2610425T3 (es) | 2010-08-27 | 2017-04-27 | Neonc Technologies Inc. | Composiciones farmacéuticas que comprenden carbamatos de alcohol perilílico |
CN105616391B (zh) | 2010-12-17 | 2021-03-19 | 尼昂克技术公司 | 使用异紫苏醇的方法和装置 |
CN102366405A (zh) * | 2011-10-21 | 2012-03-07 | 江阴长风医药科技有限公司 | 以氢氟烷烃为抛射剂的氟替卡松丙酸酯气雾剂制剂 |
SG10201703243QA (en) * | 2012-02-28 | 2017-06-29 | Iceutica Holdings Inc | Inhalable pharmaceutical compositions |
WO2014140648A1 (en) | 2013-03-15 | 2014-09-18 | Verona Pharma Plc | Drug combination |
SI3231444T1 (sl) | 2014-05-12 | 2020-04-30 | Verona Pharma Plc | Novo zdravljenje |
WO2016130800A2 (en) | 2015-02-12 | 2016-08-18 | Neonc Technologies Inc. | Pharmaceutical compositions comprising perillyl alcohol derivatives |
CN106546751A (zh) * | 2016-11-16 | 2017-03-29 | 广州华弘生物科技有限公司 | 用于检测oct4蛋白的酶联免疫试剂盒 |
JP7144411B2 (ja) | 2016-11-30 | 2022-09-29 | ネオンク テクノロジーズ インク. | ペリリルアルコール-3-ブロモピルベート複合体及びがんの治療方法 |
JP7325425B2 (ja) | 2018-02-08 | 2023-08-14 | ネオンク テクノロジーズ インク. | 血液脳関門を透過性にする方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141674A (en) * | 1984-03-08 | 1992-08-25 | Phares Pharmaceutical Research N.V. | Methods of preparing pro-liposome dispersions and aerosols |
WO1988001165A1 (en) * | 1986-08-11 | 1988-02-25 | Innovata Biomed Limited | Pharmaceutical formulations comprising microcapsules |
GB9024365D0 (en) * | 1990-11-09 | 1991-01-02 | Glaxo Group Ltd | Medicaments |
EP0655237A1 (de) * | 1993-11-27 | 1995-05-31 | Hoechst Aktiengesellschaft | Medizinische Aerosolformulierung |
GB9426252D0 (en) * | 1994-12-24 | 1995-02-22 | Glaxo Group Ltd | Pharmaceutical composition |
US5876760A (en) * | 1995-06-12 | 1999-03-02 | Ono Pharmaceutical Co., Ltd. | Granules containing pranlukast, process for producing the granules, and method of improving adhesiveness of pranlukast |
GB9606677D0 (en) * | 1996-03-29 | 1996-06-05 | Glaxo Wellcome Inc | Process and device |
EP0952821A4 (en) * | 1996-12-31 | 2006-07-26 | Nektar Therapeutics | METHODS FOR DRYING AQUEOUS SUSPENSION OF HYDROPHOBIC DRUGS WITH HYDROPHILIC EXCIPIENTS AND COMPOSITIONS PREPARED THEREFROM |
-
1999
- 1999-04-15 CA CA002328882A patent/CA2328882A1/en not_active Abandoned
- 1999-04-15 HU HU0101608A patent/HUP0101608A2/hu unknown
- 1999-04-15 AR ARP990101747A patent/AR018183A1/es unknown
- 1999-04-15 AU AU35231/99A patent/AU755066B2/en not_active Ceased
- 1999-04-15 EA EA200000956A patent/EA200000956A1/ru unknown
- 1999-04-15 ID IDW20002392A patent/ID27887A/id unknown
- 1999-04-15 JP JP2000544308A patent/JP2002512183A/ja not_active Ceased
- 1999-04-15 CN CNB998072818A patent/CN1145478C/zh not_active Expired - Fee Related
- 1999-04-15 DE DE69904312T patent/DE69904312T2/de not_active Expired - Fee Related
- 1999-04-15 MA MA25536A patent/MA26621A1/fr unknown
- 1999-04-15 PL PL99343491A patent/PL343491A1/xx unknown
- 1999-04-15 KR KR1020007011572A patent/KR20010042816A/ko not_active Application Discontinuation
- 1999-04-15 CO CO99022532A patent/CO5021210A1/es unknown
- 1999-04-15 EP EP99916921A patent/EP1073417B1/en not_active Expired - Lifetime
- 1999-04-15 NZ NZ507619A patent/NZ507619A/en unknown
- 1999-04-15 AP APAP/P/2000/001961A patent/AP2000001961A0/en unknown
- 1999-04-15 PT PT99916921T patent/PT1073417E/pt unknown
- 1999-04-15 ES ES99916921T patent/ES2189410T3/es not_active Expired - Lifetime
- 1999-04-15 AT AT99916921T patent/ATE228823T1/de not_active IP Right Cessation
- 1999-04-15 BR BR9909736-2A patent/BR9909736A/pt not_active Application Discontinuation
- 1999-04-15 WO PCT/EP1999/002535 patent/WO1999053901A1/en not_active Application Discontinuation
- 1999-04-15 IL IL13908799A patent/IL139087A0/xx unknown
- 1999-04-15 DK DK99916921T patent/DK1073417T3/da active
- 1999-04-15 TR TR2001/00144T patent/TR200100144T2/tr unknown
- 1999-04-15 EE EEP200000608A patent/EE200000608A/xx unknown
- 1999-04-16 PE PE1999000318A patent/PE20000433A1/es not_active Application Discontinuation
-
2000
- 2000-10-13 IS IS5665A patent/IS5665A/is unknown
- 2000-10-17 NO NO20005218A patent/NO20005218L/no not_active Application Discontinuation
- 2000-10-18 HR HR20000689A patent/HRP20000689A2/hr not_active Application Discontinuation
-
2003
- 2003-02-11 US US10/364,257 patent/US7521042B2/en not_active Expired - Fee Related
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