TR199802386T2 - Benzofuran karboksamidler ve bunlar�n terap�tik kullan�m�. - Google Patents

Benzofuran karboksamidler ve bunlar�n terap�tik kullan�m�.

Info

Publication number
TR199802386T2
TR199802386T2 TR1998/02386T TR9802386T TR199802386T2 TR 199802386 T2 TR199802386 T2 TR 199802386T2 TR 1998/02386 T TR1998/02386 T TR 1998/02386T TR 9802386 T TR9802386 T TR 9802386T TR 199802386 T2 TR199802386 T2 TR 199802386T2
Authority
TR
Turkey
Prior art keywords
therapeutic use
benzofuran carboxamides
disease states
carboxamides
benzofuran
Prior art date
Application number
TR1998/02386T
Other languages
English (en)
Turkish (tr)
Inventor
Joan Dyke Hazel
Gary Montana John
Lowe Christopher
Jayne Kendall Hannah
Margaret Sabin Verity
Original Assignee
Darwin Discovery Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9610515.0A external-priority patent/GB9610515D0/en
Priority claimed from PCT/GB1996/003012 external-priority patent/WO1997020833A1/en
Priority claimed from GBGB9708070.9A external-priority patent/GB9708070D0/en
Application filed by Darwin Discovery Limited filed Critical Darwin Discovery Limited
Publication of TR199802386T2 publication Critical patent/TR199802386T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TR1998/02386T 1996-05-20 1997-05-20 Benzofuran karboksamidler ve bunlar�n terap�tik kullan�m�. TR199802386T2 (xx)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9610515.0A GB9610515D0 (en) 1996-05-20 1996-05-20 Novel compounds
PCT/GB1996/003012 WO1997020833A1 (en) 1995-12-05 1996-12-05 Benzofuran carboxamides and sulphonamides
GBGB9708070.9A GB9708070D0 (en) 1997-04-22 1997-04-22 Compounds

Publications (1)

Publication Number Publication Date
TR199802386T2 true TR199802386T2 (xx) 1999-02-22

Family

ID=26309366

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/02386T TR199802386T2 (xx) 1996-05-20 1997-05-20 Benzofuran karboksamidler ve bunlar�n terap�tik kullan�m�.

Country Status (19)

Country Link
US (2) US5925636A (cg-RX-API-DMAC10.html)
EP (1) EP0901482B1 (cg-RX-API-DMAC10.html)
JP (1) JP2000510848A (cg-RX-API-DMAC10.html)
CN (1) CN1219171A (cg-RX-API-DMAC10.html)
AT (1) ATE239004T1 (cg-RX-API-DMAC10.html)
BR (1) BR9709113A (cg-RX-API-DMAC10.html)
CA (1) CA2252537A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ371998A3 (cg-RX-API-DMAC10.html)
DE (1) DE69721526T2 (cg-RX-API-DMAC10.html)
ES (1) ES2193376T3 (cg-RX-API-DMAC10.html)
HU (1) HUP0100042A3 (cg-RX-API-DMAC10.html)
IL (1) IL126558A (cg-RX-API-DMAC10.html)
NO (1) NO985375D0 (cg-RX-API-DMAC10.html)
NZ (1) NZ332340A (cg-RX-API-DMAC10.html)
PL (1) PL329912A1 (cg-RX-API-DMAC10.html)
RU (1) RU2162467C2 (cg-RX-API-DMAC10.html)
SK (1) SK282676B6 (cg-RX-API-DMAC10.html)
TR (1) TR199802386T2 (cg-RX-API-DMAC10.html)
WO (1) WO1997044337A1 (cg-RX-API-DMAC10.html)

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WO2002012189A1 (en) * 2000-08-09 2002-02-14 Mitsubishi Pharma Corporation Fused bicyclic amide compounds and medicinal use thereof
US6953774B2 (en) 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation
DK1463493T3 (da) 2001-12-14 2008-02-04 Serono Lab Fremgangsmåder til at inducere æglösning ved anvendelse af en ikke polypeptid-cAMP-niveaumodulator
PT1489078E (pt) * 2002-03-28 2010-02-24 Mitsubishi Tanabe Pharma Corp Derivados de benzofurano
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ES2195785B1 (es) * 2002-05-16 2005-03-16 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
DE10238257B4 (de) * 2002-08-21 2007-04-19 Johannes-Gutenberg-Universität Mainz Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
US20050215626A1 (en) * 2003-09-25 2005-09-29 Wyeth Substituted benzofuran oximes
TW200524915A (en) * 2003-09-26 2005-08-01 Tanabe Seiyaku Co Carbamoyl-type benzofuran derivatives
ES2251866B1 (es) * 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
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EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
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AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
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US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
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EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
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CN100434426C (zh) * 2006-10-10 2008-11-19 中国科学院昆明植物研究所 盐肤木内酯a,其制备方法和其在制药中的应用
CN101631792B (zh) * 2007-02-28 2013-05-01 利奥制药有限公司 新的磷酸二酯酶抑制剂
SI2114951T1 (sl) * 2007-02-28 2014-08-29 Leo Pharma A/S Novi zaviralci fosfodiesteraze
ES2320954B1 (es) * 2007-03-02 2010-03-16 Laboratorio Almirall S.A. Nuevo procedimiento de preparacion de 3-metil-4-fenilisoxazolo (3,4-d)iridazin-7(6h)-ona.
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PL2406253T3 (pl) * 2009-03-11 2013-10-31 Pfizer Pochodne benzofuranylu jako inhibitory glukokinazy
SI2585469T1 (sl) * 2010-06-24 2016-11-30 Leo Pharma A/S Heterociklične spojine benzodioksola ali benzodioksepina kot zaviralci fostodiesteraze
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Also Published As

Publication number Publication date
BR9709113A (pt) 1999-08-03
EP0901482A1 (en) 1999-03-17
SK160498A3 (en) 1999-06-11
IL126558A0 (en) 1999-08-17
HUP0100042A3 (en) 2003-01-28
EP0901482B1 (en) 2003-05-02
PL329912A1 (en) 1999-04-26
WO1997044337A1 (en) 1997-11-27
DE69721526D1 (de) 2003-06-05
CN1219171A (zh) 1999-06-09
SK282676B6 (sk) 2002-11-06
ES2193376T3 (es) 2003-11-01
NO985375L (no) 1998-11-19
RU2162467C2 (ru) 2001-01-27
NO985375D0 (no) 1998-11-19
NZ332340A (en) 2000-04-28
CZ371998A3 (cs) 1999-03-17
DE69721526T2 (de) 2004-04-08
JP2000510848A (ja) 2000-08-22
ATE239004T1 (de) 2003-05-15
US5925636A (en) 1999-07-20
HUP0100042A2 (hu) 2002-01-28
US5972936A (en) 1999-10-26
IL126558A (en) 2002-07-25
CA2252537A1 (en) 1997-11-27

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