TR199700453A2 - Orto-ikame edilmi� benzoilguanidin'ler, bunlar�n imal edilmesine mahsus usul, bunlar�n ila� ya da diyagnostik madde olarak kullan�lmalar� ve bunlar� ihtive eden ila�. - Google Patents
Orto-ikame edilmi� benzoilguanidin'ler, bunlar�n imal edilmesine mahsus usul, bunlar�n ila� ya da diyagnostik madde olarak kullan�lmalar� ve bunlar� ihtive eden ila�.Info
- Publication number
- TR199700453A2 TR199700453A2 TR97/00453A TR9700453A TR199700453A2 TR 199700453 A2 TR199700453 A2 TR 199700453A2 TR 97/00453 A TR97/00453 A TR 97/00453A TR 9700453 A TR9700453 A TR 9700453A TR 199700453 A2 TR199700453 A2 TR 199700453A2
- Authority
- TR
- Turkey
- Prior art keywords
- drug
- ortho
- manufacture
- diagnostic agent
- substituted benzoylguanidines
- Prior art date
Links
- AJDQRQQNNLZLPM-UHFFFAOYSA-N n-(diaminomethylidene)benzamide Chemical class NC(N)=NC(=O)C1=CC=CC=C1 AJDQRQQNNLZLPM-UHFFFAOYSA-N 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 2
- 239000003814 drug Substances 0.000 title 2
- 229940039227 diagnostic agent Drugs 0.000 title 1
- 239000000032 diagnostic agent Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 206010061216 Infarction Diseases 0.000 abstract 2
- 230000007574 infarction Effects 0.000 abstract 2
- 230000000302 ischemic effect Effects 0.000 abstract 2
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 230000003293 cardioprotective effect Effects 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 238000011161 development Methods 0.000 abstract 1
- 230000018109 developmental process Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000001991 pathophysiological effect Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19622370A DE19622370A1 (de) | 1996-06-04 | 1996-06-04 | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199700453A2 true TR199700453A2 (xx) | 1997-12-21 |
Family
ID=7796095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR97/00453A TR199700453A2 (xx) | 1996-06-04 | 1997-06-02 | Orto-ikame edilmi� benzoilguanidin'ler, bunlar�n imal edilmesine mahsus usul, bunlar�n ila� ya da diyagnostik madde olarak kullan�lmalar� ve bunlar� ihtive eden ila�. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US6011063A (enExample) |
| EP (1) | EP0811610B1 (enExample) |
| JP (1) | JP4101904B2 (enExample) |
| KR (1) | KR980002019A (enExample) |
| CN (1) | CN1064956C (enExample) |
| AR (1) | AR008761A1 (enExample) |
| AT (1) | ATE209630T1 (enExample) |
| AU (1) | AU723665B2 (enExample) |
| BR (1) | BR9703440A (enExample) |
| CA (1) | CA2206758C (enExample) |
| CZ (1) | CZ289411B6 (enExample) |
| DE (2) | DE19622370A1 (enExample) |
| DK (1) | DK0811610T3 (enExample) |
| ES (1) | ES2166487T3 (enExample) |
| HR (1) | HRP970304B1 (enExample) |
| HU (1) | HUP9700989A3 (enExample) |
| ID (1) | ID17038A (enExample) |
| IL (1) | IL120988A0 (enExample) |
| MX (1) | MX9704094A (enExample) |
| NO (1) | NO310188B1 (enExample) |
| NZ (1) | NZ314973A (enExample) |
| PL (1) | PL185757B1 (enExample) |
| PT (1) | PT811610E (enExample) |
| RU (1) | RU2214397C2 (enExample) |
| SI (1) | SI0811610T1 (enExample) |
| SK (1) | SK282628B6 (enExample) |
| TR (1) | TR199700453A2 (enExample) |
| TW (1) | TW429243B (enExample) |
| ZA (1) | ZA974869B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410563B1 (en) | 1999-12-22 | 2002-06-25 | Merck Frosst Canada & Co. | Substituted 8-arylquinoline phosphodiesterase-4 inhibitors |
| US6639077B2 (en) | 2000-03-23 | 2003-10-28 | Merck Frosst Canada & Co. | Tri-aryl-substituted-ethane PDE4 inhibitors |
| MY123585A (en) | 2000-03-23 | 2006-05-31 | Merck Canada Inc | Tri-aryl-substituted-ethane pde4 inhibitors. |
| JP2003534328A (ja) | 2000-05-25 | 2003-11-18 | メルク フロスト カナダ アンド カンパニー | フルオロアルコキシ置換ベンズアミドジクロロピリジニルｎ−オキシドｐｄｅ４阻害剤 |
| US6740666B2 (en) | 2000-12-20 | 2004-05-25 | Merck & Co., Inc. | Substituted 8-arylquinoline phosphodiesterase-4 inhibitors |
| WO2002094823A1 (en) | 2001-05-24 | 2002-11-28 | Merck Frosst Canada & Co. | 1-biaryl-1,8-napthyridin-4-one phosphodiesterase-4 inhibitors |
| JO2311B1 (en) | 2001-08-29 | 2005-09-12 | ميرك فروست كندا ليمتد | Alkyl inhibitors Ariel phosphodiesterase-4 |
| WO2003077918A1 (en) | 2002-03-12 | 2003-09-25 | Merck & Co., Inc. | Di-aryl substituted tetrazole modulators of metabotropic glutamate receptor-5 |
| GB0916163D0 (en) * | 2009-09-15 | 2009-10-28 | Shire Llc | Prodrugs of guanfacine |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ284456B6 (cs) * | 1992-02-15 | 1998-12-16 | Hoechst Aktiengesellschaft | Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje |
| EP0612723B1 (de) * | 1993-02-20 | 1997-08-27 | Hoechst Aktiengesellschaft | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament |
| DE4318756A1 (de) * | 1993-06-05 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4327244A1 (de) * | 1993-08-13 | 1995-02-16 | Hoechst Ag | Harnstoffsubstituierte Benzoylguandine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4422685A1 (de) * | 1994-06-29 | 1996-01-04 | Hoechst Ag | Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1996
- 1996-06-04 DE DE19622370A patent/DE19622370A1/de not_active Withdrawn
-
1997
- 1997-05-22 EP EP97108258A patent/EP0811610B1/de not_active Expired - Lifetime
- 1997-05-22 ES ES97108258T patent/ES2166487T3/es not_active Expired - Lifetime
- 1997-05-22 DE DE59705495T patent/DE59705495D1/de not_active Expired - Lifetime
- 1997-05-22 DK DK97108258T patent/DK0811610T3/da active
- 1997-05-22 AT AT97108258T patent/ATE209630T1/de not_active IP Right Cessation
- 1997-05-22 SI SI9730284T patent/SI0811610T1/xx unknown
- 1997-05-22 PT PT97108258T patent/PT811610E/pt unknown
- 1997-05-30 NZ NZ314973A patent/NZ314973A/en unknown
- 1997-06-02 ID IDP971869A patent/ID17038A/id unknown
- 1997-06-02 AU AU24650/97A patent/AU723665B2/en not_active Ceased
- 1997-06-02 AR ARP970102385A patent/AR008761A1/es unknown
- 1997-06-02 TW TW086107502A patent/TW429243B/zh active
- 1997-06-02 TR TR97/00453A patent/TR199700453A2/xx unknown
- 1997-06-02 SK SK696-97A patent/SK282628B6/sk unknown
- 1997-06-02 CN CN971054797A patent/CN1064956C/zh not_active Expired - Fee Related
- 1997-06-02 CZ CZ19971696A patent/CZ289411B6/cs not_active IP Right Cessation
- 1997-06-03 KR KR1019970022785A patent/KR980002019A/ko not_active Ceased
- 1997-06-03 HU HU9700989A patent/HUP9700989A3/hu unknown
- 1997-06-03 MX MX9704094A patent/MX9704094A/es unknown
- 1997-06-03 US US08/868,077 patent/US6011063A/en not_active Expired - Lifetime
- 1997-06-03 PL PL97320327A patent/PL185757B1/pl not_active IP Right Cessation
- 1997-06-03 NO NO19972527A patent/NO310188B1/no not_active IP Right Cessation
- 1997-06-03 ZA ZA9704869A patent/ZA974869B/xx unknown
- 1997-06-03 JP JP14439397A patent/JP4101904B2/ja not_active Expired - Fee Related
- 1997-06-03 HR HR970304A patent/HRP970304B1/xx not_active IP Right Cessation
- 1997-06-03 RU RU97109913/04A patent/RU2214397C2/ru not_active IP Right Cessation
- 1997-06-03 IL IL12098897A patent/IL120988A0/xx unknown
- 1997-06-04 CA CA002206758A patent/CA2206758C/en not_active Expired - Fee Related
- 1997-06-04 BR BR9703440A patent/BR9703440A/pt not_active IP Right Cessation
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