TNSN99129A1 - Formulations intranasales de mesylate de sildenafil et procede pour leur preparation - Google Patents
Formulations intranasales de mesylate de sildenafil et procede pour leur preparationInfo
- Publication number
- TNSN99129A1 TNSN99129A1 TNTNSN99129A TNSN99129A TNSN99129A1 TN SN99129 A1 TNSN99129 A1 TN SN99129A1 TN TNSN99129 A TNTNSN99129 A TN TNSN99129A TN SN99129 A TNSN99129 A TN SN99129A TN SN99129 A1 TNSN99129 A1 TN SN99129A1
- Authority
- TN
- Tunisia
- Prior art keywords
- intranasal formulations
- sildenafil mesylate
- preparation
- intranasal
- sildenafil
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Otolaryngology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'INVENTION CONCERNE LE MESYLATE DE SILDENAFIL AINSI QUE LE MONO OU DIHYDRATE CRISTALLIN DE MESYLATE DE SILDENAFIL, ET DES FORMULATIONS INTRANASALES LE CONTENANT. LADITE FORMULATION INTRANASALE EST SOUS FORME D'UNE SOLUTION AQUEUSE OU SOUS FORME DE POUDRE. APPLICATION : UTILISATION DE CES FORMULATIONS INTRANASALES POUR LE TRAITEMENT D'UN DISFONCTIONNEMENT DE L'ERECTION MASCULINE OU DE TROUBLES SEXUELS FEMININS.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9813452.1A GB9813452D0 (en) | 1998-06-22 | 1998-06-22 | Pharmaceutical formulations |
GBGB9820837.4A GB9820837D0 (en) | 1998-09-24 | 1998-09-24 | Pharmaceutical formulations |
GBGB9903177.5A GB9903177D0 (en) | 1999-02-13 | 1999-02-13 | Pharmaceutical formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
TNSN99129A1 true TNSN99129A1 (fr) | 2005-11-10 |
Family
ID=27269368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNTNSN99129A TNSN99129A1 (fr) | 1998-06-22 | 1999-06-21 | Formulations intranasales de mesylate de sildenafil et procede pour leur preparation |
Country Status (40)
Country | Link |
---|---|
US (2) | US20020040139A1 (fr) |
EP (1) | EP0967214B1 (fr) |
JP (1) | JP3263379B2 (fr) |
KR (1) | KR100345824B1 (fr) |
AP (1) | AP1178A (fr) |
AR (1) | AR016993A1 (fr) |
AT (1) | ATE269866T1 (fr) |
AU (1) | AU746865B2 (fr) |
BG (1) | BG64372B1 (fr) |
BR (1) | BR9903273A (fr) |
CA (1) | CA2275554C (fr) |
CZ (1) | CZ294856B6 (fr) |
DE (1) | DE69918222T2 (fr) |
DK (1) | DK0967214T3 (fr) |
DZ (1) | DZ2826A1 (fr) |
EA (1) | EA001903B1 (fr) |
ES (1) | ES2221733T3 (fr) |
GT (1) | GT199900095A (fr) |
HN (1) | HN1999000096A (fr) |
HR (1) | HRP990195B1 (fr) |
HU (1) | HUP9902076A3 (fr) |
ID (1) | ID23554A (fr) |
IL (1) | IL130539A0 (fr) |
IS (1) | IS5085A (fr) |
MA (1) | MA25089A1 (fr) |
MY (1) | MY117967A (fr) |
NO (1) | NO317365B1 (fr) |
NZ (1) | NZ336382A (fr) |
OA (1) | OA11069A (fr) |
PA (1) | PA8476301A1 (fr) |
PE (1) | PE20000702A1 (fr) |
PT (1) | PT967214E (fr) |
SG (1) | SG77246A1 (fr) |
SI (1) | SI0967214T1 (fr) |
SK (1) | SK284574B6 (fr) |
TN (1) | TNSN99129A1 (fr) |
TR (1) | TR199901444A2 (fr) |
TW (1) | TWI223598B (fr) |
UA (1) | UA59385C2 (fr) |
YU (1) | YU29699A (fr) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6200591B1 (en) | 1998-06-25 | 2001-03-13 | Anwar A. Hussain | Method of administration of sildenafil to produce instantaneous response for the treatment of erectile dysfunction |
GB9828340D0 (en) * | 1998-12-22 | 1999-02-17 | Novartis Ag | Organic compounds |
CA2391968A1 (fr) * | 1999-11-18 | 2001-05-25 | Natco Pharma Limited | Composition pharmaceutique amelioree pour traiter la dyserection masculine |
KR20010016165A (ko) * | 2000-11-16 | 2001-03-05 | 정순학 | 성기능 장애 치료를 위한 피부에 적용하는 제제 |
DE10118306A1 (de) | 2001-04-12 | 2002-10-17 | Bayer Ag | Imidazotriazinonhaltige Zusammensetzungen zur nasalen Applikation |
DE10118305A1 (de) * | 2001-04-12 | 2002-10-17 | Bayer Ag | Zusammensetzungen zur nasalen Applikation |
US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
WO2002094219A2 (fr) * | 2001-05-24 | 2002-11-28 | Alexza Molecular Delivery Corporation | Administration par voie pulmonaire de medicaments contre les troubles de l'erection |
US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
US7766013B2 (en) | 2001-06-05 | 2010-08-03 | Alexza Pharmaceuticals, Inc. | Aerosol generating method and device |
US6737042B2 (en) | 2001-05-24 | 2004-05-18 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
DE10248601B4 (de) * | 2002-10-17 | 2006-05-24 | Goldstein, Naum, Dr.habil.nat. | Pharmazeutisches Mittel zur endonasalen Applikation bei der Behandlung von Krankheiten und Störungen des zentralen Nervensystems |
US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
US7138107B2 (en) * | 2003-02-18 | 2006-11-21 | Compellis Pharmaceuticals | Inhibition of olfactory neurosensory function to treat eating disorders and obesity |
WO2004073729A1 (fr) * | 2003-02-21 | 2004-09-02 | Translational Research Ltd. | Compositions destinees a l'administration nasale d'un medicament |
EP1607117A4 (fr) | 2003-03-27 | 2007-10-24 | Bioactis Ltd | Applicateur de medicament en poudre pour cavite nasale |
AR043880A1 (es) * | 2003-04-22 | 2005-08-17 | Solvay Pharm Gmbh | Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas |
EP1625333A1 (fr) | 2003-05-21 | 2006-02-15 | Alexza Pharmaceuticals, Inc. | Unite de chauffage autonome et unite de fourniture de medicament faisant appel a cette unite de chauffage |
US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
WO2006016530A1 (fr) * | 2004-08-10 | 2006-02-16 | Translational Research, Ltd. | Composition transnasale dont l’action est immédiate et l’absorbabilité est élevée |
US8268791B2 (en) * | 2004-08-25 | 2012-09-18 | Aegis Therapeutics, Llc. | Alkylglycoside compositions for drug administration |
US20140162965A1 (en) | 2004-08-25 | 2014-06-12 | Aegis Therapeutics, Inc. | Compositions for oral drug administration |
US20090047347A1 (en) * | 2005-07-29 | 2009-02-19 | Aegis Therapeutics, Inc. | Compositions for Drug Administration |
US9895444B2 (en) | 2004-08-25 | 2018-02-20 | Aegis Therapeutics, Llc | Compositions for drug administration |
US20060046962A1 (en) | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
US8524274B2 (en) | 2004-10-18 | 2013-09-03 | Polymun Scientific Immunbiologische Forschung Gmbh | Liposomal composition comprising an active ingredient for relaxing smooth muscle, the production of this composition and the therapeutic use thereof |
CA2600636A1 (fr) * | 2005-03-09 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Nouvelles compositions pharmaceutiques a base d'anticholinergiques et d'inhibiteurs de pde 5 |
ME01609B (me) | 2005-04-19 | 2014-09-20 | Takeda Gmbh | Roflumilast za liječenje pulmonarne hipertenzije |
US8506934B2 (en) | 2005-04-29 | 2013-08-13 | Robert I. Henkin | Methods for detection of biological substances |
ES2308750T3 (es) * | 2005-08-29 | 2008-12-01 | Teva Pharmaceutical Industries Ltd | Tadalafil en particulas solidas que presenta una distribucion de particulas bimodal. |
GB0526283D0 (en) * | 2005-12-23 | 2006-02-01 | Givaudan Sa | Compositions |
GB0606234D0 (en) * | 2006-03-29 | 2006-05-10 | Pliva Istrazivanje I Razvoj D | Pharmaceutically acceptable salts and polymorphic forms |
US8226949B2 (en) | 2006-06-23 | 2012-07-24 | Aegis Therapeutics Llc | Stabilizing alkylglycoside compositions and methods thereof |
WO2008078730A1 (fr) | 2006-12-26 | 2008-07-03 | Translational Research, Ltd. | Préparation pour administration transnasale |
US8293489B2 (en) | 2007-01-31 | 2012-10-23 | Henkin Robert I | Methods for detection of biological substances |
ES2594867T3 (es) | 2007-03-09 | 2016-12-23 | Alexza Pharmaceuticals, Inc. | Unidad de calentamiento para usar en un dispositivo de administración de fármaco |
DE102008004893A1 (de) * | 2008-01-17 | 2009-07-23 | Add Technologies Ltd. | Trägerpellets, Verfahren zu deren Herstellung und deren Verwendung |
WO2009098697A1 (fr) * | 2008-02-08 | 2009-08-13 | Dexxon Ltd. | Formes pharmaceutiques de modafinil et de sildénafil |
US20090258865A1 (en) * | 2008-03-28 | 2009-10-15 | Hale Biopharma Ventures, Llc | Administration of benzodiazepine compositions |
AU2008357475B2 (en) | 2008-06-04 | 2012-11-01 | Colgate-Palmolive Company | Oral care implement with cavitation system |
WO2009152344A2 (fr) * | 2008-06-11 | 2009-12-17 | Comgenrx, Inc. | Polythérapie à base d’inhibiteurs de phosphodiestérases |
US8580801B2 (en) | 2008-07-23 | 2013-11-12 | Robert I. Henkin | Phosphodiesterase inhibitor treatment |
US8440631B2 (en) | 2008-12-22 | 2013-05-14 | Aegis Therapeutics, Llc | Compositions for drug administration |
US9101539B2 (en) * | 2009-05-15 | 2015-08-11 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal pharmaceutical compositions with improved pharmacokinetics |
JP2011001317A (ja) * | 2009-06-19 | 2011-01-06 | Fumakilla Ltd | 鼻用洗浄剤 |
WO2011013003A2 (fr) * | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Granisétron pour administration intranasale et applicateur nasal |
US9993433B2 (en) | 2010-05-10 | 2018-06-12 | Euro-Celtique S.A. | Manufacturing of active-free granules and tablets comprising the same |
JP5840201B2 (ja) | 2010-05-10 | 2016-01-06 | ユーロ−セルティーク エス.エイ. | 活性剤を負荷した顆粒と追加の活性剤の組合せ |
CN107737100A (zh) | 2011-06-14 | 2018-02-27 | 哈尔生物药投资有限责任公司 | 苯二氮卓组合物的投与 |
CN102952138B (zh) * | 2011-08-17 | 2016-07-06 | 上海特化医药科技有限公司 | 一种吡唑并嘧啶酮化合物的盐、多晶型物及其药物组合物、制备方法和应用 |
GB2497933B (en) * | 2011-12-21 | 2014-12-24 | Londonpharma Ltd | Drug delivery technology |
WO2014055801A1 (fr) * | 2012-10-05 | 2014-04-10 | Henkin Robert I | Inhibiteurs de la phosphodiestérase destinés à traiter des troubles du goût et de l'odorat |
CA2881144A1 (fr) * | 2012-11-09 | 2014-05-09 | Purdue Pharma | Compositions pharmaceutiques comprenant de l'hydromorphone et de la naloxone |
RU2536425C2 (ru) * | 2013-01-17 | 2014-12-20 | Общество с ограниченной ответственностью "Фармамед" | Фармацевтическая композиция, содержащая силденафил цитрат, и способ ее приготовления |
WO2014143453A1 (fr) * | 2013-03-15 | 2014-09-18 | Henkin Robert I | Traitement faisaint intervenir un inhibiteur de la phosphodiestérase |
US9814710B2 (en) | 2013-11-13 | 2017-11-14 | Euro-Celtique S.A. | Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome |
WO2015126944A1 (fr) | 2014-02-18 | 2015-08-27 | Henkin Robert I | Procédés et compositions permettant de diagnostiquer et de traiter une perte et/ou une distorsion du goût ou de l'odorat |
NO2723977T3 (fr) | 2014-03-19 | 2018-03-10 | ||
CA2994709A1 (fr) * | 2015-08-03 | 2017-02-09 | Synergistic Therapeutics, Llc | Gel therapeutique pour dysfonctionnement sexuel |
WO2018076074A1 (fr) * | 2016-10-31 | 2018-05-03 | Suda Ltd | Administration de principes actifs par voie muqueuse |
CA3055094A1 (fr) * | 2017-03-02 | 2018-09-07 | Dutch Renewable Energy B.V. | Administration intranasale de substances physiologiquement actives |
US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
US11464778B2 (en) * | 2017-12-26 | 2022-10-11 | Liqmeds Worldwide Limited | Liquid oral formulations for sildenafil |
JP6941224B2 (ja) | 2018-02-06 | 2021-09-29 | イージス セラピューティクス,エルエルシー | 疾患の処置のための鼻腔内エピネフリン製剤及び方法 |
WO2019200427A1 (fr) * | 2018-04-16 | 2019-10-24 | Barista Mist Pty Ltd | Compositions de caféine et procédés d'utilisation |
SE542968C2 (en) * | 2018-10-26 | 2020-09-22 | Lindahl Anders | Treatment of osteoarthritis |
CA3187753A1 (fr) * | 2020-07-29 | 2022-02-03 | Lido Ventures Llc | Appareil, systeme et procede pour faciliter le traitement intranasal d'un patient |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5250534A (en) * | 1990-06-20 | 1993-10-05 | Pfizer Inc. | Pyrazolopyrimidinone antianginal agents |
GB9311920D0 (en) * | 1993-06-09 | 1993-07-28 | Pfizer Ltd | Therapeutic agents |
US5565466A (en) * | 1993-08-13 | 1996-10-15 | Zonagen, Inc. | Methods for modulating the human sexual response |
DE69600784T2 (de) * | 1995-11-20 | 1999-04-08 | Lilly Co Eli | Proteinkinase-C-Inhibitor |
EP0992240A4 (fr) * | 1997-05-29 | 2003-04-16 | Mochida Pharm Co Ltd | Agent therapeutique destine a traiter l'anerection |
CA2312839C (fr) * | 1997-12-02 | 2008-01-15 | Lisbeth Illum | Compositions pour administration nasale |
US6087368A (en) * | 1998-06-08 | 2000-07-11 | Bristol-Myers Squibb Company | Quinazolinone inhibitors of cGMP phosphodiesterase |
-
1999
- 1999-05-29 TW TW088108934A patent/TWI223598B/zh active
- 1999-06-08 SI SI9930594T patent/SI0967214T1/xx unknown
- 1999-06-08 ES ES99304425T patent/ES2221733T3/es not_active Expired - Lifetime
- 1999-06-08 AT AT99304425T patent/ATE269866T1/de not_active IP Right Cessation
- 1999-06-08 DE DE69918222T patent/DE69918222T2/de not_active Expired - Fee Related
- 1999-06-08 PT PT99304425T patent/PT967214E/pt unknown
- 1999-06-08 EP EP99304425A patent/EP0967214B1/fr not_active Expired - Lifetime
- 1999-06-08 DK DK99304425T patent/DK0967214T3/da active
- 1999-06-15 HN HN1999000096A patent/HN1999000096A/es unknown
- 1999-06-17 SK SK819-99A patent/SK284574B6/sk unknown
- 1999-06-17 SG SG1999002935A patent/SG77246A1/en unknown
- 1999-06-17 AP APAP/P/1999/001585A patent/AP1178A/en active
- 1999-06-17 IL IL13053999A patent/IL130539A0/xx unknown
- 1999-06-18 HR HR990195A patent/HRP990195B1/xx not_active IP Right Cessation
- 1999-06-18 OA OA9900137A patent/OA11069A/en unknown
- 1999-06-18 MY MYPI99002521A patent/MY117967A/en unknown
- 1999-06-18 AR ARP990102946A patent/AR016993A1/es unknown
- 1999-06-18 IS IS5085A patent/IS5085A/is unknown
- 1999-06-18 CA CA002275554A patent/CA2275554C/fr not_active Expired - Fee Related
- 1999-06-18 US US09/335,628 patent/US20020040139A1/en not_active Abandoned
- 1999-06-18 PE PE1999000543A patent/PE20000702A1/es not_active Application Discontinuation
- 1999-06-21 HU HU9902076A patent/HUP9902076A3/hu unknown
- 1999-06-21 JP JP17392599A patent/JP3263379B2/ja not_active Expired - Fee Related
- 1999-06-21 TN TNTNSN99129A patent/TNSN99129A1/fr unknown
- 1999-06-21 AU AU35794/99A patent/AU746865B2/en not_active Ceased
- 1999-06-21 NZ NZ336382A patent/NZ336382A/xx unknown
- 1999-06-21 DZ DZ990126A patent/DZ2826A1/fr active
- 1999-06-21 UA UA99063463A patent/UA59385C2/uk unknown
- 1999-06-21 KR KR1019990023169A patent/KR100345824B1/ko not_active IP Right Cessation
- 1999-06-21 EA EA199900487A patent/EA001903B1/ru not_active IP Right Cessation
- 1999-06-21 NO NO19993051A patent/NO317365B1/no unknown
- 1999-06-21 PA PA19998476301A patent/PA8476301A1/es unknown
- 1999-06-21 ID IDP990592D patent/ID23554A/id unknown
- 1999-06-21 BG BG103510A patent/BG64372B1/bg unknown
- 1999-06-21 MA MA25639A patent/MA25089A1/fr unknown
- 1999-06-21 CZ CZ19992257A patent/CZ294856B6/cs not_active IP Right Cessation
- 1999-06-22 YU YU29699A patent/YU29699A/sh unknown
- 1999-06-22 TR TR1999/01444A patent/TR199901444A2/xx unknown
- 1999-06-22 BR BR9903273-2A patent/BR9903273A/pt not_active IP Right Cessation
- 1999-06-22 GT GT199900095A patent/GT199900095A/es unknown
-
2003
- 2003-03-14 US US10/389,127 patent/US20030158206A1/en not_active Abandoned
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TNSN99106A1 (fr) | Derives d'isothiazole nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
TNSN99155A1 (fr) | 1-aryl-3-arylmethyl-1,8-naphtyridine-4(1h)-ones nouvelles, procede pour leur preparation et compositions pharmaceutiques les contenant | |
TNSN00199A1 (fr) | PYRAZOLO [4,3-d] PYRIMIDINES-7-ONES PHARMACEUTIQUEMENT ACTIVES, LEUR PREPARATION ET MEDICAMENTS LES CONTENANT | |
TNSN99169A1 (fr) | Derives de 4,4-biarylpiperidine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant | |
TNSN97144A1 (fr) | Derives 6,6-heterobicycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant | |
TNSN99171A1 (fr) | 4-carboxyamino-2-substitue-1,2,3,4-tetrahydroquinoleines, procede pour leur preparation et compositions pharmaceutiques les contenant | |
TNSN98216A1 (fr) | Derives d'acide hydrauxamique, compositions pharmaceutiques les contenant et procede pour leur preparation | |
TNSN99236A1 (fr) | Derives bicycliques substitues nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
TNSN98112A1 (fr) | Composes dipeptidiques | |
TNSN00065A1 (fr) | Derives nouveaux de pyrimidine inhibiteurs de sorbitol- deshydrogenase, leur procede de preparation et compositions pharmaceutiques les contenant. | |
TNSN98154A1 (fr) | Derives de 2-aminopyridine nouveaux et compositions pharmaceutiques les contenant | |
TNSN97145A1 (fr) | Derives 6,5-heterobicycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant | |
TNSN98017A1 (fr) | Derives de sulfonyluree, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
TNSN98024A1 (fr) | 2-amino-6-(2-substitue-4-phenoxy)-substitue-pyridines, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
TNSN99147A1 (fr) | Procede d'emulsification | |
TNSN98194A1 (fr) | Derives nouveaux de 6-o-methylerythromycine a, procede pour leur preparation et compositions pharmaceutiques les contenant | |
TNSN98104A1 (fr) | Agonistes de prostaglandines, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
TNSN99031A1 (fr) | Composes heterocycliques nouveaux inhibiteurs de romatases, procede pour leur preparation et compositions pharmaceutiques les contenant |