TNSN98211A1 - Association d'un inhibiteur d'aldose-reductase et d'un inhibiteur de glycogene-phosphorylase, et composition pharmaceutique la contenant - Google Patents

Association d'un inhibiteur d'aldose-reductase et d'un inhibiteur de glycogene-phosphorylase, et composition pharmaceutique la contenant

Info

Publication number
TNSN98211A1
TNSN98211A1 TNTNSN98211A TNSN98211A TNSN98211A1 TN SN98211 A1 TNSN98211 A1 TN SN98211A1 TN TNSN98211 A TNTNSN98211 A TN TNSN98211A TN SN98211 A TNSN98211 A TN SN98211A TN SN98211 A1 TNSN98211 A1 TN SN98211A1
Authority
TN
Tunisia
Prior art keywords
inhibitor
glycogene
aldose
combination
pharmaceutical composition
Prior art date
Application number
TNTNSN98211A
Other languages
English (en)
Inventor
Lakshman Mylari Banavara
Hulin Bernard
Lee Treadway Judith
Jay Hoover Dennis
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN98211A1 publication Critical patent/TNSN98211A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Noise Elimination (AREA)
  • Superheterodyne Receivers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'INVENTION CONCERNE DES ASSOCIATIONS D'INHIBITEURS D'ALDOSE - REDUCTASE ET D'INHIBITEURS DE GLYCOGENE-PHOSPHORYLASE. ELLE CONCERNE EGALEMENT DES COMPOSITIONS PHARMACEUTIQUES CONTENANT CES ASSOCIATIONS. APPLICATION : UTILISATION DE CES COMPOSITIONS POUR LE TRAITEMENT D'ETATS DE RESISTANCE A L'INSULINE TELS QUE LE DIABETE ET POUR LA REDUCTION D'UNE ALTERATION TISSULAIRE DUE A UNE ISCHEMIE.
TNTNSN98211A 1997-11-21 1998-11-18 Association d'un inhibiteur d'aldose-reductase et d'un inhibiteur de glycogene-phosphorylase, et composition pharmaceutique la contenant TNSN98211A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6636597P 1997-11-21 1997-11-21

Publications (1)

Publication Number Publication Date
TNSN98211A1 true TNSN98211A1 (fr) 2005-03-15

Family

ID=22069038

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN98211A TNSN98211A1 (fr) 1997-11-21 1998-11-18 Association d'un inhibiteur d'aldose-reductase et d'un inhibiteur de glycogene-phosphorylase, et composition pharmaceutique la contenant

Country Status (38)

Country Link
EP (1) EP1032424B9 (fr)
JP (1) JP2002504478A (fr)
KR (2) KR20010032304A (fr)
CN (1) CN1279617A (fr)
AP (1) AP911A (fr)
AR (1) AR016423A1 (fr)
AT (1) ATE205403T1 (fr)
AU (1) AU733304B2 (fr)
BG (1) BG104435A (fr)
BR (1) BR9814698A (fr)
CA (1) CA2310069A1 (fr)
DE (1) DE69801680T2 (fr)
DK (1) DK1032424T3 (fr)
DZ (1) DZ2656A1 (fr)
EA (1) EA002365B1 (fr)
ES (1) ES2161548T3 (fr)
GR (1) GR3037071T3 (fr)
GT (1) GT199800166A (fr)
HR (1) HRP20000327A2 (fr)
HU (1) HUP0100272A3 (fr)
ID (1) ID24524A (fr)
IL (1) IL135713A0 (fr)
IS (1) IS5453A (fr)
MA (1) MA26568A1 (fr)
NO (1) NO20002164L (fr)
OA (1) OA11379A (fr)
PA (1) PA8462301A1 (fr)
PE (1) PE135399A1 (fr)
PL (1) PL340643A1 (fr)
PT (1) PT1032424E (fr)
SK (1) SK7222000A3 (fr)
TN (1) TNSN98211A1 (fr)
TR (1) TR200001451T2 (fr)
UA (1) UA57811C2 (fr)
UY (1) UY25258A1 (fr)
WO (1) WO1999026659A1 (fr)
YU (1) YU30700A (fr)
ZA (1) ZA9810636B (fr)

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JP2003520226A (ja) 2000-01-21 2003-07-02 ノバルティス アクチエンゲゼルシャフト ジペプチジルペプチダーゼ−ｉｖ阻害剤および抗糖尿病薬剤を含む組合せ物
CO5271699A1 (es) * 2000-01-24 2003-04-30 Pfizer Prod Inc Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa
US6570013B2 (en) 2000-02-16 2003-05-27 Pfizer Inc Salts of zopolrestat
US6395767B2 (en) 2000-03-10 2002-05-28 Bristol-Myers Squibb Company Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
IL144507A0 (en) * 2000-07-31 2002-05-23 Pfizer Prod Inc Use of glycogen phosphorylase inhibitors to inhibit tumor growth
WO2002098429A1 (fr) * 2001-06-07 2002-12-12 Pfizer Products Inc. Formes salines du zopolrestat, a savoir ethanolamine, diethanolamine ou triethanolamine
GB0205176D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205165D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205170D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205166D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205162D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
GB0205175D0 (en) 2002-03-06 2002-04-17 Astrazeneca Ab Chemical compounds
US7057046B2 (en) 2002-05-20 2006-06-06 Bristol-Myers Squibb Company Lactam glycogen phosphorylase inhibitors and method of use
CA2392486A1 (fr) 2002-07-05 2002-12-08 Duchesnay Inc. Forme posologique pharmaceutique portant une inscription pour les femmes enceintes
US7098235B2 (en) 2002-11-14 2006-08-29 Bristol-Myers Squibb Co. Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
US7767828B2 (en) 2003-11-12 2010-08-03 Phenomix Corporation Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7317109B2 (en) 2003-11-12 2008-01-08 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
ES2524916T3 (es) 2003-11-12 2014-12-15 Sino-Med International Alliance, Inc. Compuestos heterocíclicos de ácido borónico
US7576121B2 (en) 2003-11-12 2009-08-18 Phenomix Corporation Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
WO2006017292A1 (fr) 2004-07-12 2006-02-16 Phenomix Corporation Composes cyano contraints
US7365061B2 (en) 2004-11-15 2008-04-29 Bristol-Myers Squibb Company 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US7223786B2 (en) 2004-11-15 2007-05-29 Bristol-Myers Squibb Company 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors
US7214704B2 (en) 2004-11-15 2007-05-08 Bristol-Myers Squibb Company 2-Amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US7226942B2 (en) 2004-11-15 2007-06-05 Bristol-Myers Squibb Company 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
US20060235028A1 (en) 2005-04-14 2006-10-19 Li James J Inhibitors of 11-beta hydroxysteroid dehydrogenase type I
US7825139B2 (en) 2005-05-25 2010-11-02 Forest Laboratories Holdings Limited (BM) Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US20070060528A1 (en) 2005-09-14 2007-03-15 Christopher Ronald J Administration of dipeptidyl peptidase inhibitors
EP2046753A2 (fr) 2006-07-06 2009-04-15 Brystol-Myers Squibb Company Inhibiteurs de type i de la 11-bêta hydroxystéroïde déshydrogénase pyridone/hydroxypyridine
US7727978B2 (en) 2006-08-24 2010-06-01 Bristol-Myers Squibb Company Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
WO2008130951A1 (fr) 2007-04-17 2008-10-30 Bristol-Myers Squibb Company Inhibiteurs de 11-bêta-hydroxystéroïde déshydrogénase hétérocyclique condensés de type i
ES2388967T3 (es) 2007-05-04 2012-10-22 Bristol-Myers Squibb Company Agonistas [6,6]- y [6,7]-bicíclicos del receptor GPR119 acoplado a la proteína G
JP2010526146A (ja) 2007-05-04 2010-07-29 ブリストル−マイヤーズ スクイブ カンパニー ［６，５］−二環式ｇｐｒ１１９ｇタンパク質結合受容体アゴニスト
PE20090888A1 (es) 2007-07-17 2009-07-15 Bristol Myers Squibb Co Compuestos heterociclicos como agentes moduladores del receptor acoplado a la proteina g gpr119
TW201006821A (en) 2008-07-16 2010-02-16 Bristol Myers Squibb Co Pyridone and pyridazone analogues as GPR119 modulators
WO2011041293A1 (fr) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Dérivés pyrazolo [1, 5—a] pyrimidines comme inhibiteurs de kinase 1 régulatrice de signal d'apoptose
PT2531501E (pt) 2010-02-03 2014-02-17 Takeda Pharmaceutical Inibidores da cinase de regulação do sinal de apoptose 1
EA201270755A1 (ru) 2010-04-08 2013-03-29 Бристол-Майерс Сквибб Компани Аналоги пиримидинилпиперидинилоксипиридинона в качестве модуляторов рецептора gpr119
WO2011130459A1 (fr) 2010-04-14 2011-10-20 Bristol-Myers Squibb Company Nouveaux activateurs de la glucokinase et méthodes d'utilisation desdits activateurs
EA201270778A1 (ru) 2010-05-06 2013-04-30 Бристол-Майерс Сквибб Компани Бициклические гетероарильные аналоги в качестве модуляторов рецептора gpr119
EP2566862B1 (fr) 2010-05-06 2015-09-16 Bristol-Myers Squibb Company Analogues de benzofuranyle en tant que modulateurs de gpr119
HUE026715T2 (en) 2011-01-20 2016-07-28 Bionevia Pharmaceuticals Inc Modified release pharmaceutical composition comprising Epalrestat or a derivative thereof and methods of their use
EP2850073B1 (fr) 2012-05-16 2017-07-19 Bristol-Myers Squibb Company Analogues de pyrimidinylpipéridinyloxypyridone en tant que modulateurs de gpr119
WO2015061272A1 (fr) 2013-10-22 2015-04-30 Bristol-Myers Squibb Company Inhibiteurs de triazolopyridine 11-bêta hydroxystéroïde déshydrogénase de type 1 à marquage isotopique
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EP0343273B1 (fr) * 1988-05-27 1994-04-27 Deutsche ITT Industries GmbH Circuit de correction pour une paire de signaux numériques en quadrature
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JP3068200B2 (ja) * 1995-06-06 2000-07-24 ファイザー・インコーポレーテッド グリコーゲンホスホリラーゼ阻害剤としての置換ｎ−（インドール−２−カルボニル−）アミドおよび誘導体
CA2224062C (fr) * 1995-06-06 2001-09-04 Pfizer Limited (indole-2-carbonyl-)-glycinamides substitues en n et leurs derives, servant d'inhibiteurs de la glycogene phosphorylase

Also Published As

Publication number Publication date
SK7222000A3 (en) 2001-09-11
MA26568A1 (fr) 2004-12-20
ES2161548T3 (es) 2001-12-01
EA200000433A1 (ru) 2000-12-25
HUP0100272A2 (hu) 2001-06-28
EA002365B1 (ru) 2002-04-25
EP1032424A1 (fr) 2000-09-06
PL340643A1 (en) 2001-02-12
PA8462301A1 (es) 2000-05-24
WO1999026659A1 (fr) 1999-06-03
CA2310069A1 (fr) 1999-06-03
DE69801680T2 (de) 2002-02-07
AU9555898A (en) 1999-06-15
DE69801680D1 (de) 2001-10-18
KR20010032300A (ko) 2001-04-16
HRP20000327A2 (en) 2001-02-28
GR3037071T3 (en) 2002-01-31
ZA9810636B (en) 2000-05-22
DK1032424T3 (da) 2001-11-19
PT1032424E (pt) 2001-12-28
HUP0100272A3 (en) 2002-11-28
OA11379A (en) 2004-01-28
IL135713A0 (en) 2001-05-20
NO20002164L (no) 2000-07-19
DZ2656A1 (fr) 2003-03-22
KR20010032304A (ko) 2001-04-16
TR200001451T2 (tr) 2002-06-21
ID24524A (id) 2000-07-20
UA57811C2 (uk) 2003-07-15
CN1279617A (zh) 2001-01-10
BR9814698A (pt) 2000-10-03
AP911A (en) 2000-12-07
ATE205403T1 (de) 2001-09-15
GT199800166A (es) 2000-04-19
KR100661214B1 (ko) 2006-12-26
PE135399A1 (es) 2000-01-15
JP2002504478A (ja) 2002-02-12
AR016423A1 (es) 2001-07-04
AU733304B2 (en) 2001-05-10
AP9801401A0 (en) 1998-12-31
UY25258A1 (es) 2000-12-29
EP1032424B9 (fr) 2004-10-06
IS5453A (is) 2000-04-14
EP1032424B1 (fr) 2001-09-12
NO20002164D0 (no) 2000-04-27
BG104435A (bg) 2001-01-31
YU30700A (sh) 2002-12-10

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