SU733517A3 - Способ получени триазинонов - Google Patents

Способ получени триазинонов Download PDF

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Publication number
SU733517A3
SU733517A3 SU782594701A SU2594701A SU733517A3 SU 733517 A3 SU733517 A3 SU 733517A3 SU 782594701 A SU782594701 A SU 782594701A SU 2594701 A SU2594701 A SU 2594701A SU 733517 A3 SU733517 A3 SU 733517A3
Authority
SU
USSR - Soviet Union
Prior art keywords
het
general formula
triazin
methyl
mixture
Prior art date
Application number
SU782594701A
Other languages
English (en)
Russian (ru)
Inventor
Генри Браун Томас
Джон Айф Роберт
Original Assignee
Смит Клайн Энд Френч Лабораториз Лтд (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Смит Клайн Энд Френч Лабораториз Лтд (Фирма) filed Critical Смит Клайн Энд Френч Лабораториз Лтд (Фирма)
Application granted granted Critical
Publication of SU733517A3 publication Critical patent/SU733517A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Herstellung von neuen 1,2,4~Triazin-5-on-Derivaten der allgemeinen Formel I, in der Het', Z', Y und χ die im Erfindungsanspruch angegebene Bedeutung haben, und ihren Salzen mit Säuren, Hydraten und Hydratsalzen. Diese Verbindungen sind Histamin-Hi-und-H2-Receptor-Antagonisten. - Formel I
SU782594701A 1977-03-19 1978-03-17 Способ получени триазинонов SU733517A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB11757/77A GB1601132A (en) 1977-03-19 1977-03-19 Pharmacologically active triazinones

Publications (1)

Publication Number Publication Date
SU733517A3 true SU733517A3 (ru) 1980-05-05

Family

ID=9992150

Family Applications (1)

Application Number Title Priority Date Filing Date
SU782594701A SU733517A3 (ru) 1977-03-19 1978-03-17 Способ получени триазинонов

Country Status (20)

Country Link
AR (1) AR223643A1 (de)
BE (1) BE864992A (de)
BG (1) BG33157A3 (de)
CS (1) CS208746B2 (de)
DD (1) DD134522A5 (de)
DK (1) DK121978A (de)
EG (1) EG13240A (de)
ES (1) ES467953A1 (de)
FI (1) FI780629A (de)
GB (1) GB1601132A (de)
GR (1) GR66122B (de)
HU (1) HU175669B (de)
IT (1) IT1095458B (de)
NO (1) NO148556C (de)
PL (1) PL110686B1 (de)
PT (1) PT67687B (de)
SE (1) SE7803113L (de)
SU (1) SU733517A3 (de)
YU (1) YU65278A (de)
ZA (1) ZA78988B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309435A (en) 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
US4394508A (en) * 1980-06-07 1983-07-19 Bristol-Myers Company Chemical compounds
AU2192683A (en) * 1982-12-30 1984-07-05 Biomeasure Incorporated Pyrazolo(1,5-alpha)-1,3,5-triazines
GB0113343D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel Heterocycles 2

Also Published As

Publication number Publication date
DD134522A5 (de) 1979-03-07
IT1095458B (it) 1985-08-10
NO148556B (no) 1983-07-25
NO148556C (no) 1983-11-02
BG33157A3 (en) 1982-12-15
ES467953A1 (es) 1978-11-01
BE864992A (fr) 1978-09-18
PL110686B1 (en) 1980-07-31
NO780970L (no) 1978-09-20
CS208746B2 (en) 1981-09-15
IT7820754A0 (it) 1978-02-28
AR223643A1 (es) 1981-09-15
DK121978A (da) 1978-09-20
PL205382A1 (pl) 1979-03-26
PT67687B (en) 1979-07-23
SE7803113L (sv) 1978-09-20
GB1601132A (en) 1981-10-28
EG13240A (en) 1980-12-31
PT67687A (en) 1978-03-01
FI780629A (fi) 1978-09-20
YU65278A (en) 1982-08-31
ZA78988B (en) 1979-06-27
GR66122B (de) 1981-01-16
HU175669B (de) 1980-09-28

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