SU507243A3 - Способ получени производных теофиллина - Google Patents

Способ получени производных теофиллина

Info

Publication number
SU507243A3
SU507243A3 SU2066925A SU2066925A SU507243A3 SU 507243 A3 SU507243 A3 SU 507243A3 SU 2066925 A SU2066925 A SU 2066925A SU 2066925 A SU2066925 A SU 2066925A SU 507243 A3 SU507243 A3 SU 507243A3
Authority
SU
USSR - Soviet Union
Prior art keywords
theophylline
obtaining derivatives
derivatives
obtaining
carried out
Prior art date
Application number
SU2066925A
Other languages
English (en)
Inventor
Денгель Фердинанд
Эрманн Оскар
Фридрих Лудвиг
Циммерманн Франк
Original Assignee
Кноль Аг (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кноль Аг (Фирма) filed Critical Кноль Аг (Фирма)
Application granted granted Critical
Publication of SU507243A3 publication Critical patent/SU507243A3/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Description

(54) СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ ТЕОФИЛЛИНЛ
CHrtH2-NH-tHr СНг где RI и R2 имеют выщеуказанные значе ш , метилируют у основного азота с последующим выделением целевого продукта известным приемом . Введение метильной группы во вторичные основани  общей II дл  перевода их в 25 сх)единени  общей формулы I можно проводить обработкой метилгалогенидами или диметилсульфатом , а также кип чением с формалином или параформальдегидом и муравьиной кислотой. Металирование можно также осуществл ть, встр хива 
SU2066925A 1972-08-08 1974-10-09 Способ получени производных теофиллина SU507243A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2239012A DE2239012A1 (de) 1972-08-08 1972-08-08 Basisch substituierte theophyllinabkoemmlinge

Publications (1)

Publication Number Publication Date
SU507243A3 true SU507243A3 (ru) 1976-03-15

Family

ID=5853037

Family Applications (5)

Application Number Title Priority Date Filing Date
SU1952731A SU504490A3 (ru) 1972-08-08 1973-07-25 Способ получени производных теофиллина
SU2065458A SU526291A3 (ru) 1972-08-08 1974-10-09 Способ получени производных теофиллина
SU2066925A SU507243A3 (ru) 1972-08-08 1974-10-09 Способ получени производных теофиллина
SU2065457A SU507241A3 (ru) 1972-08-08 1974-10-09 Способ получени производных теофиллина
SU2065464A SU507242A3 (ru) 1972-08-08 1974-10-09 Способ получени производных теофиллина

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SU1952731A SU504490A3 (ru) 1972-08-08 1973-07-25 Способ получени производных теофиллина
SU2065458A SU526291A3 (ru) 1972-08-08 1974-10-09 Способ получени производных теофиллина

Family Applications After (2)

Application Number Title Priority Date Filing Date
SU2065457A SU507241A3 (ru) 1972-08-08 1974-10-09 Способ получени производных теофиллина
SU2065464A SU507242A3 (ru) 1972-08-08 1974-10-09 Способ получени производных теофиллина

Country Status (26)

Country Link
US (1) US3926995A (ru)
JP (1) JPS5714350B2 (ru)
KR (1) KR780000273B1 (ru)
AR (4) AR206915A1 (ru)
AT (3) AT327218B (ru)
AU (1) AU473294B2 (ru)
BE (1) BE801893A (ru)
CA (1) CA998669A (ru)
CH (4) CH591484A5 (ru)
CS (1) CS189616B2 (ru)
DD (1) DD107044A5 (ru)
DE (1) DE2239012A1 (ru)
DK (1) DK131187B (ru)
ES (1) ES415782A1 (ru)
FI (1) FI58640C (ru)
FR (1) FR2195441B1 (ru)
GB (1) GB1431587A (ru)
HU (1) HU170289B (ru)
IE (1) IE37899B1 (ru)
IL (1) IL42698A (ru)
NL (1) NL7310951A (ru)
NO (1) NO137900C (ru)
SE (1) SE400081B (ru)
SU (5) SU504490A3 (ru)
YU (3) YU206473A (ru)
ZA (1) ZA735400B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49121524U (ru) * 1973-02-12 1974-10-17
JPS5242609U (ru) * 1975-09-20 1977-03-26
JPS62277347A (ja) * 1986-02-25 1987-12-02 Microbial Chem Res Found 新規生理活性物質ア−ブスタチン類縁化合物
JPS6332704A (ja) * 1986-07-26 1988-02-12 Sony Corp 回転磁気ヘツド装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3245994A (en) * 1966-04-12 Theophylline derivatives
US3036083A (en) * 1959-05-15 1962-05-22 Ciba Geigy Corp Certain 2-pyridyl lower alkyl guanidines
FR1352320A (fr) * 1963-02-13 1964-02-14 Degussa Procédé de préparation de dérivés alcoylxanthiniques à substituants basiques
DE1237578B (de) * 1963-05-10 1967-03-30 Knoll Ag Verfahren zur Herstellung basisch substituierter Xanthinderivate
NL6708305A (ru) * 1966-06-23 1967-12-27
DE2021620C3 (de) * 1970-05-02 1980-02-07 Boehringer Sohn Ingelheim Neue Phenylaminoalkane und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
CH591483A5 (ru) 1977-09-30
YU217679A (en) 1983-01-21
IL42698A0 (en) 1973-10-25
IL42698A (en) 1976-07-30
SU507241A3 (ru) 1976-03-15
ATA257875A (de) 1975-06-15
AU5902873A (en) 1975-02-13
ATA678473A (de) 1975-04-15
DE2239012A1 (de) 1974-02-21
NL7310951A (ru) 1974-02-12
YU206473A (en) 1982-05-31
FR2195441A1 (ru) 1974-03-08
IE37899L (en) 1974-02-08
NO137900C (no) 1978-05-16
JPS5714350B2 (ru) 1982-03-24
BE801893A (fr) 1974-01-04
YU217779A (en) 1983-01-21
SU504490A3 (ru) 1976-02-25
CA998669A (en) 1976-10-19
GB1431587A (en) 1976-04-07
AU473294B2 (en) 1976-06-17
AR206914A1 (es) 1976-08-31
SE400081B (sv) 1978-03-13
AT328464B (de) 1976-03-25
AR206916A1 (es) 1976-08-31
KR780000273B1 (en) 1978-07-24
AT328465B (de) 1976-03-25
CS189616B2 (en) 1979-04-30
ES415782A1 (es) 1976-07-01
DK131187C (ru) 1975-11-17
HU170289B (ru) 1977-05-28
JPS4945096A (ru) 1974-04-27
DD107044A5 (ru) 1974-07-12
CH591485A5 (ru) 1977-09-30
IE37899B1 (en) 1977-11-09
FR2195441B1 (ru) 1977-09-09
CH591484A5 (ru) 1977-09-30
FI58640C (fi) 1981-03-10
ATA257975A (de) 1975-06-15
SU507242A3 (ru) 1976-03-15
AT327218B (de) 1976-01-26
DK131187B (da) 1975-06-09
NO137900B (no) 1978-02-06
US3926995A (en) 1975-12-16
FI58640B (fi) 1980-11-28
AR206913A1 (es) 1976-08-31
AR206915A1 (es) 1976-08-31
CH590865A5 (ru) 1977-08-31
ZA735400B (en) 1974-07-31
SU526291A3 (ru) 1976-08-25

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