CH549590A - Procede de preparation de derives d'acides pyrazolo (3,4b)pyridine-5-carboxyliques. - Google Patents

Procede de preparation de derives d'acides pyrazolo (3,4b)pyridine-5-carboxyliques.

Info

Publication number
CH549590A
CH549590A CH179774A CH179774A CH549590A CH 549590 A CH549590 A CH 549590A CH 179774 A CH179774 A CH 179774A CH 179774 A CH179774 A CH 179774A CH 549590 A CH549590 A CH 549590A
Authority
CH
Switzerland
Prior art keywords
pyrazolo
pyridine
preparation
carboxylic acid
acid derivatives
Prior art date
Application number
CH179774A
Other languages
English (en)
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of CH549590A publication Critical patent/CH549590A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CH179774A 1971-08-05 1972-08-04 Procede de preparation de derives d'acides pyrazolo (3,4b)pyridine-5-carboxyliques. CH549590A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16953671A 1971-08-05 1971-08-05

Publications (1)

Publication Number Publication Date
CH549590A true CH549590A (fr) 1974-05-31

Family

ID=22616112

Family Applications (3)

Application Number Title Priority Date Filing Date
CH179674A CH553800A (fr) 1971-08-05 1972-08-04 Procede de preparation de derives amino d'acides pyrazolo (3,4-b)pyridine-5-carboxyliques.
CH179774A CH549590A (fr) 1971-08-05 1972-08-04 Procede de preparation de derives d'acides pyrazolo (3,4b)pyridine-5-carboxyliques.
CH1161072A CH553798A (fr) 1971-08-05 1972-08-04 Procede de preparation de derives amino d'acides pyrazolo (3,4-b)pyridine-5-carboxyliques.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH179674A CH553800A (fr) 1971-08-05 1972-08-04 Procede de preparation de derives amino d'acides pyrazolo (3,4-b)pyridine-5-carboxyliques.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1161072A CH553798A (fr) 1971-08-05 1972-08-04 Procede de preparation de derives amino d'acides pyrazolo (3,4-b)pyridine-5-carboxyliques.

Country Status (17)

Country Link
US (1) US3755340A (fr)
JP (3) JPS5637237B2 (fr)
AR (2) AR199280A1 (fr)
AU (1) AU462839B2 (fr)
BE (1) BE787249A (fr)
CA (1) CA997350A (fr)
CH (3) CH553800A (fr)
DE (1) DE2237765A1 (fr)
ES (2) ES405553A1 (fr)
FR (1) FR2150737B1 (fr)
GB (1) GB1402172A (fr)
HU (1) HU164519B (fr)
IE (1) IE36600B1 (fr)
NL (1) NL176365C (fr)
PH (2) PH10047A (fr)
YU (1) YU35138B (fr)
ZA (1) ZA724745B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984422A (en) * 1972-06-16 1976-10-05 E. R. Squibb & Sons, Inc. Amino derivatives of [4,3-c]pyrazolopyridine carboxylic acids and esters
US3835144A (en) * 1972-06-16 1974-09-10 Squibb & Sons Inc Amino derivatives of (4,3-c pyrazolopyridine cabroxylic acids and esters
US3957782A (en) * 1974-12-16 1976-05-18 E. R. Squibb & Sons, Inc. Pyrazolo [3,4-b]pyrazine-5-carboxylic acids, esters, nitriles and amides
US3996233A (en) * 1975-02-10 1976-12-07 E. R. Squibb & Sons, Inc. Amino derivatives of imidazo[4,5-b]pyridines
US4038283A (en) * 1975-04-30 1977-07-26 E. R. Squibb & Sons, Inc. 4-Alkoxy or hydroxy derivatives of 2H-pyrazolo[3,4-b]pyridine-5-carboxylic acids and esters
CA1071207A (fr) * 1975-04-30 1980-02-05 Theodor Denzel Derives 4-amino d'acides 2h-pyrazole (3,4-b) pyridine-5-carboxyliques et de leurs esters
US3985760A (en) * 1975-09-11 1976-10-12 E. R. Squibb & Sons, Inc. Amino derivatives of 6-phenylisoxazolo[5,4-b]pyridines
JPS531041U (fr) * 1976-06-22 1978-01-07
US4364948A (en) * 1981-09-28 1982-12-21 Ici Americas Inc. Pyrazolo[3,4-b]pyridine compounds
US4511568A (en) * 1982-05-12 1985-04-16 Ici Americas Inc. CNS-Depressant pyrazolopyridines
US4552883A (en) * 1982-06-15 1985-11-12 Ici Americas Inc. Pyrazolo[3,4-b]pyridine carboxylic acid esters and their pharmaceutical use
IT1154024B (it) * 1982-09-22 1987-01-21 Lepetit Spa Derivati pridinici e procedimento per la loro produzione
GB8425104D0 (en) * 1984-10-04 1984-11-07 Ici America Inc Amide derivatives
JPH0522500Y2 (fr) * 1984-12-27 1993-06-10
JPS61113659U (fr) * 1984-12-28 1986-07-18
EP0204571B1 (fr) 1985-06-07 1992-01-22 Ici Americas Inc. Dérivés difluoro choisis
JPS62103137U (fr) * 1985-12-20 1987-07-01
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
JPS63188572U (fr) * 1987-05-28 1988-12-02
GB9716161D0 (en) 1997-08-01 1997-10-08 Zeneca Ltd Process
CA2314355A1 (fr) * 1997-12-13 1999-06-24 Bristol-Myers Squibb Company Utilisation de pyrazolo¢3,4-b!pyridine en tant qu'inhibiteurs de kinase dependant de la cycline
US6326379B1 (en) 1998-09-16 2001-12-04 Bristol-Myers Squibb Co. Fused pyridine inhibitors of cGMP phosphodiesterase
CN100387598C (zh) * 2002-09-16 2008-05-14 葛兰素集团有限公司 吡唑并[3,4-b]吡啶化合物及其作为磷酸二酯酶抑制剂的用途
GB0230045D0 (en) 2002-12-23 2003-01-29 Glaxo Group Ltd Compounds
CA2557004A1 (fr) * 2003-12-19 2005-06-30 Glaxo Group Limited Composes pyrazolo [3,4-b] pyridine et leur utilisation en tant qu'inhibiteurs de la phosphodiesterase
GB0405937D0 (en) * 2004-03-16 2004-04-21 Glaxo Group Ltd Compounds
WO2005090352A1 (fr) * 2004-03-16 2005-09-29 Glaxo Group Limited Compose de pyrazolo[3,4-b]pyridine, et son utilisation en tant qu'inhibiteur de pdea4
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
CN101616661A (zh) * 2006-12-20 2009-12-30 阿斯利康(瑞典)有限公司 化合物及其用途
TW200908968A (en) 2007-05-29 2009-03-01 Sgx Pharmaceuticals Inc Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators
UY31637A1 (es) * 2008-02-06 2009-08-03 Farmacoforos duales-antagonistas muscarinicos de pde4
UY31636A1 (es) * 2008-02-06 2009-08-03 Farmacoforos duales-antagonistas muscarinicos de pde4
CL2009000248A1 (es) * 2008-02-06 2009-09-11 Glaxo Group Ltd Compuestos derivados de pirazolo [3,4-b] piridin-5-il, inhibidores de la fosfodiesterasa de tipo iv (pde4) y antagonista de receptores muscarinicos de acetilcolina (machr); composicion farmaceutica que los comprende; y su uso en la preparacion de medicamentos utiles en el tratamiento de enferemedades respiratorias y alergicas

Also Published As

Publication number Publication date
CH553798A (fr) 1974-09-13
ES405553A1 (es) 1975-07-01
JPS597703B2 (ja) 1984-02-20
IE36600B1 (en) 1976-12-08
JPS5637237B2 (fr) 1981-08-29
PH13781A (en) 1980-09-26
NL7210701A (fr) 1973-02-07
JPS5622768A (en) 1981-03-03
US3755340A (en) 1973-08-28
JPS4826796A (fr) 1973-04-09
FR2150737B1 (fr) 1975-06-20
FR2150737A1 (fr) 1973-04-13
PH10047A (en) 1976-07-27
NL176365B (nl) 1984-11-01
JPS5745440B2 (fr) 1982-09-28
AU4514672A (en) 1974-02-07
YU202072A (en) 1980-03-15
AR199294A1 (es) 1974-08-23
AU462839B2 (en) 1975-07-10
ZA724745B (en) 1973-04-25
DE2237765A1 (de) 1973-02-08
YU35138B (en) 1980-09-25
BE787249A (fr) 1973-02-05
JPS5622784A (en) 1981-03-03
HU164519B (fr) 1974-02-28
GB1402172A (en) 1975-08-06
CA997350A (en) 1976-09-21
ES413941A1 (es) 1976-06-01
AR199280A1 (es) 1974-08-23
NL176365C (nl) 1985-04-01
IE36600L (en) 1973-02-05
CH553800A (fr) 1974-09-13

Similar Documents

Publication Publication Date Title
CH549590A (fr) Procede de preparation de derives d'acides pyrazolo (3,4b)pyridine-5-carboxyliques.
RO78465A (fr) Procede de preparation des derives des acides 1,2-benzisoxazolcarboxyliques
RO68652A (fr) Procede pour la preparation d'acides 2-pyrolidino-5-oxo-8-alkyle-5,8-dihydro-pyrido-(2,3-d)-pyrimidine-6-carboxyliques
RO63871A (fr) Procede pour la preparation des derives du pyrazolo-(1,5-a)-pyrymidine
DK138424B (da) Analogifremgangsmåde til fremstilling af 5-oxopyrido(2,3-d)pyrimidin-6-carboxylsyre-derivater.
CH550757A (fr) Procede de preparation d'acides cyclopropylmethylphenylacetiques.
CH551437A (fr) Procede de preparation d'acides chromone-carboxyliques.
FR2316239A1 (fr) Procede de preparation de 2,4-dioxo-1,2,3,4-tetrahydro-s-triazino-(1,2-a)-benzimidazoles
CH557320A (fr) Procede de preparation de nouveaux derives de l'acide butyrique.
CH551446A (fr) Procede de preparation de nouveaux derives de l'adenosine.
SE402009B (sv) Forfarande for framstellning av 9-desoxi-prosta-5,9,(10),13-triensyraderivat
RO64918A (fr) Procede pour la preparation des derives des acides pyrimido-(4,5-b)-quinoline-4(3h)-one-2-carboxyliques
CH553820A (fr) Procede de preparation d'acides (alpha)-amidinothioacetamidocephalosporaniques.
FI50988C (fi) Menetelmä beetta-(3-keto-7alfa-tioasetyyli-17beetta-hydroksi-4-androst en-17alfa-yyli)propionihappo-gamma-laktonin valmistamiseksi.
BE826343A (fr) Procede de preparation de s-triazolo(3,4- bbenzothiazoles
BE814249A (fr) Procede de preparation de phtalazino (2,3-b)
BE820047A (fr) Procede de preparation d'hexahydrothieno (3,4-d) imidazole-2,4-diones
CH550195A (fr) Procede de preparation de derives d'isoxazolopyridinecetones.
CH555345A (fr) Procede de preparation de nouveaux derives du type adenosinecarboxylate-5'.
CH551408A (fr) Procede de preparation de nouveaux derives de (alpha)-dialkylamino-alkoxy-6- dimethoxy-4,7- benzofurannes.
CH554898A (fr) Procede de preparation de derives d'acide 2-(thiocarbonylamino)acetamidocephalosporanique.
BE790056A (fr) Procede de preparation de 1, 1'-dianthraquinonyles
RO68650A (fr) Procede pour la preparation des imidazole-(1,2-a)-procede pour la preparation des imidazole-(1,2-a)ss-triazines -triazines
CH550192A (fr) Procede de preparation de nouveaux derives de l'acide thiohydroximique.
FR2307812A1 (fr) Procede de production de pyrazolo(3,4-b)pyridine-cetones

Legal Events

Date Code Title Description
PL Patent ceased