ES405553A1 - Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin-5-carboxilicos. - Google Patents

Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin-5-carboxilicos.

Info

Publication number
ES405553A1
ES405553A1 ES405553A ES405553A ES405553A1 ES 405553 A1 ES405553 A1 ES 405553A1 ES 405553 A ES405553 A ES 405553A ES 405553 A ES405553 A ES 405553A ES 405553 A1 ES405553 A1 ES 405553A1
Authority
ES
Spain
Prior art keywords
esters
carboxylic acids
amino derivatives
pyrazolopyridine
pyrazolopyridine carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES405553A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of ES405553A1 publication Critical patent/ES405553A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
ES405553A 1971-08-05 1972-08-04 Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin-5-carboxilicos. Expired ES405553A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16953671A 1971-08-05 1971-08-05

Publications (1)

Publication Number Publication Date
ES405553A1 true ES405553A1 (es) 1975-07-01

Family

ID=22616112

Family Applications (2)

Application Number Title Priority Date Filing Date
ES405553A Expired ES405553A1 (es) 1971-08-05 1972-08-04 Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin-5-carboxilicos.
ES413941A Expired ES413941A1 (es) 1971-08-05 1973-04-19 Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin - 5 - carboxilicos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES413941A Expired ES413941A1 (es) 1971-08-05 1973-04-19 Un procedimiento para preparar nuevos derivados aminicos deacidos pirazolo (3,4-b) piridin - 5 - carboxilicos.

Country Status (17)

Country Link
US (1) US3755340A (es)
JP (3) JPS5637237B2 (es)
AR (2) AR199280A1 (es)
AU (1) AU462839B2 (es)
BE (1) BE787249A (es)
CA (1) CA997350A (es)
CH (3) CH549590A (es)
DE (1) DE2237765A1 (es)
ES (2) ES405553A1 (es)
FR (1) FR2150737B1 (es)
GB (1) GB1402172A (es)
HU (1) HU164519B (es)
IE (1) IE36600B1 (es)
NL (1) NL176365C (es)
PH (2) PH10047A (es)
YU (1) YU35138B (es)
ZA (1) ZA724745B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3835144A (en) * 1972-06-16 1974-09-10 Squibb & Sons Inc Amino derivatives of (4,3-c pyrazolopyridine cabroxylic acids and esters
US3984422A (en) * 1972-06-16 1976-10-05 E. R. Squibb & Sons, Inc. Amino derivatives of [4,3-c]pyrazolopyridine carboxylic acids and esters
US3957782A (en) * 1974-12-16 1976-05-18 E. R. Squibb & Sons, Inc. Pyrazolo [3,4-b]pyrazine-5-carboxylic acids, esters, nitriles and amides
US3996233A (en) * 1975-02-10 1976-12-07 E. R. Squibb & Sons, Inc. Amino derivatives of imidazo[4,5-b]pyridines
US4038283A (en) * 1975-04-30 1977-07-26 E. R. Squibb & Sons, Inc. 4-Alkoxy or hydroxy derivatives of 2H-pyrazolo[3,4-b]pyridine-5-carboxylic acids and esters
CA1071207A (en) * 1975-04-30 1980-02-05 Theodor Denzel 4-amino derivatives of 2h-pyrazolo (3,4-b) pyridine-5-carboxylic acids and esters
US3985760A (en) * 1975-09-11 1976-10-12 E. R. Squibb & Sons, Inc. Amino derivatives of 6-phenylisoxazolo[5,4-b]pyridines
JPS531041U (es) * 1976-06-22 1978-01-07
US4364948A (en) * 1981-09-28 1982-12-21 Ici Americas Inc. Pyrazolo[3,4-b]pyridine compounds
GB8310266D0 (en) * 1982-05-12 1983-05-18 Ici America Inc Pyrazolopyridine compounds
US4552883A (en) * 1982-06-15 1985-11-12 Ici Americas Inc. Pyrazolo[3,4-b]pyridine carboxylic acid esters and their pharmaceutical use
IT1154024B (it) * 1982-09-22 1987-01-21 Lepetit Spa Derivati pridinici e procedimento per la loro produzione
GB8425104D0 (en) * 1984-10-04 1984-11-07 Ici America Inc Amide derivatives
JPH0522500Y2 (es) * 1984-12-27 1993-06-10
JPS61113659U (es) * 1984-12-28 1986-07-18
ATE71934T1 (de) 1985-06-07 1992-02-15 Ici America Inc Selektionierte difluorverbindungen.
JPS62103137U (es) * 1985-12-20 1987-07-01
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
JPS63188572U (es) * 1987-05-28 1988-12-02
GB9716161D0 (en) 1997-08-01 1997-10-08 Zeneca Ltd Process
AU747705C (en) * 1997-12-13 2004-09-23 Bristol-Myers Squibb Company Use of pyrazolo (3,4-b) pyridine as cyclin dependent kinase inhibitors
US6326379B1 (en) 1998-09-16 2001-12-04 Bristol-Myers Squibb Co. Fused pyridine inhibitors of cGMP phosphodiesterase
GB0230045D0 (en) * 2002-12-23 2003-01-29 Glaxo Group Ltd Compounds
PT1539753E (pt) * 2002-09-16 2009-12-10 Glaxo Group Ltd Compostos de pirazolo(3,4-b)piridina e sua utilização como inibidores da fosfodiesterase
WO2005058892A1 (en) * 2003-12-19 2005-06-30 Glaxo Group Limited Pyrazolo [3,4-b] pyridine compounds, and their use as phosphodiesterase inhibitors
GB0405937D0 (en) * 2004-03-16 2004-04-21 Glaxo Group Ltd Compounds
CA2559629A1 (en) * 2004-03-16 2005-09-29 Glaxo Group Limited Pyrazolo[3,4-b]pyridine compound, and its use as a pde4 inhibitor
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
CN101616661A (zh) * 2006-12-20 2009-12-30 阿斯利康(瑞典)有限公司 化合物及其用途
CL2008001540A1 (es) 2007-05-29 2009-05-22 Sgx Pharmaceuticals Inc Compuestos derivados de pirrolopiridinas y pirazolopiridinas; composicion farmaceutica; y uso en el tratamiento del cancer.
TW200946525A (en) * 2008-02-06 2009-11-16 Glaxo Group Ltd Dual pharmacophores-PDE4-muscarinic antagonistics
TW201000476A (en) * 2008-02-06 2010-01-01 Glaxo Group Ltd Dual pharmacophores-PDE4-muscarinic antagonistics
AR070564A1 (es) * 2008-02-06 2010-04-21 Glaxo Group Ltd Derivados de 1h-pirazolo[3,4-b]piridin-5-ilo,inhibidores de fosfodiesterasas pde4 y antagonistas de receptores muscarinicos de acetilcolina(machr), utiles en el tratamiento y/o profilaxis de enfermedades respiratorias y alergicas,y composiciones farmaceuticas que los comprenden

Also Published As

Publication number Publication date
JPS5622768A (en) 1981-03-03
GB1402172A (en) 1975-08-06
CH553800A (fr) 1974-09-13
CH553798A (fr) 1974-09-13
HU164519B (es) 1974-02-28
FR2150737B1 (es) 1975-06-20
JPS597703B2 (ja) 1984-02-20
AU4514672A (en) 1974-02-07
NL176365B (nl) 1984-11-01
AU462839B2 (en) 1975-07-10
JPS5745440B2 (es) 1982-09-28
PH10047A (en) 1976-07-27
YU202072A (en) 1980-03-15
NL7210701A (es) 1973-02-07
JPS5637237B2 (es) 1981-08-29
ZA724745B (en) 1973-04-25
AR199280A1 (es) 1974-08-23
CA997350A (en) 1976-09-21
FR2150737A1 (es) 1973-04-13
US3755340A (en) 1973-08-28
CH549590A (fr) 1974-05-31
BE787249A (fr) 1973-02-05
IE36600L (en) 1973-02-05
IE36600B1 (en) 1976-12-08
JPS5622784A (en) 1981-03-03
ES413941A1 (es) 1976-06-01
YU35138B (en) 1980-09-25
NL176365C (nl) 1985-04-01
JPS4826796A (es) 1973-04-09
DE2237765A1 (de) 1973-02-08
AR199294A1 (es) 1974-08-23
PH13781A (en) 1980-09-26

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