SU482945A3 - Способ получени 3-(4"бром)или 3,"4"дибром(фенил)-3-(3"-пиридил)-1-(диметиламино)-пропана или его солей - Google Patents
Способ получени 3-(4"бром)или 3,"4"дибром(фенил)-3-(3"-пиридил)-1-(диметиламино)-пропана или его солейInfo
- Publication number
- SU482945A3 SU482945A3 SU1970163A SU1970163A SU482945A3 SU 482945 A3 SU482945 A3 SU 482945A3 SU 1970163 A SU1970163 A SU 1970163A SU 1970163 A SU1970163 A SU 1970163A SU 482945 A3 SU482945 A3 SU 482945A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- pyridyl
- dimethylamino
- propane
- bromine
- phenyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title description 4
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 title description 3
- 229910052794 bromium Inorganic materials 0.000 title description 2
- 150000003839 salts Chemical class 0.000 title description 2
- 125000000950 dibromo group Chemical group Br* 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 12
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 description 4
- 239000012071 phase Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- -1 3- (4-bromophenyl) 3- (3-pyridyl) -1- (dimethylamino) propane Chemical compound 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- AOJFQRQNPXYVLM-UHFFFAOYSA-N pyridin-1-ium;chloride Chemical compound [Cl-].C1=CC=[NH+]C=C1 AOJFQRQNPXYVLM-UHFFFAOYSA-N 0.000 description 2
- PWJNAUAOJDNTOS-UHFFFAOYSA-N 3-(4-bromophenyl)-3-pyridin-3-ylprop-2-enoic acid Chemical compound C=1C=CN=CC=1C(=CC(=O)O)C1=CC=C(Br)C=C1 PWJNAUAOJDNTOS-UHFFFAOYSA-N 0.000 description 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 description 1
- 125000004800 4-bromophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Br 0.000 description 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000012230 colorless oil Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 150000003222 pyridines Chemical class 0.000 description 1
- 238000009938 salting Methods 0.000 description 1
- SETMGIIITGNLAS-UHFFFAOYSA-N spizofurone Chemical compound O=C1C2=CC(C(=O)C)=CC=C2OC21CC2 SETMGIIITGNLAS-UHFFFAOYSA-N 0.000 description 1
- 229950001870 spizofurone Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7214872A SE373850B (enrdf_load_stackoverflow) | 1972-11-16 | 1972-11-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU482945A3 true SU482945A3 (ru) | 1975-08-30 |
Family
ID=20299803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1970163A SU482945A3 (ru) | 1972-11-16 | 1973-11-14 | Способ получени 3-(4"бром)или 3,"4"дибром(фенил)-3-(3"-пиридил)-1-(диметиламино)-пропана или его солей |
Country Status (17)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7909514L (sv) * | 1979-11-16 | 1981-05-17 | Astra Laekemedel Ab | Nya halofenyl-pyridyl-allylaminderivat |
-
1972
- 1972-11-16 SE SE7214872A patent/SE373850B/xx unknown
-
1973
- 1973-01-01 AR AR250614A patent/AR204160A1/es active
- 1973-10-12 ZA ZA737973A patent/ZA737973B/xx unknown
- 1973-10-18 BE BE136818A patent/BE806228A/xx not_active IP Right Cessation
- 1973-11-01 FI FI3386/73A patent/FI55652C/fi active
- 1973-11-08 ES ES420359A patent/ES420359A1/es not_active Expired
- 1973-11-08 AT AT938573A patent/AT333278B/de not_active IP Right Cessation
- 1973-11-08 NL NL7315294A patent/NL7315294A/xx not_active Application Discontinuation
- 1973-11-09 DE DE2356017A patent/DE2356017A1/de not_active Ceased
- 1973-11-13 CH CH1593973A patent/CH586679A5/xx not_active IP Right Cessation
- 1973-11-14 SU SU1970163A patent/SU482945A3/ru active
- 1973-11-14 DK DK614273AA patent/DK137898B/da not_active IP Right Cessation
- 1973-11-15 FR FR7340740A patent/FR2206942B1/fr not_active Expired
- 1973-11-15 IE IE2067/73A patent/IE38516B1/xx unknown
- 1973-11-15 CA CA185,868A patent/CA976553A/en not_active Expired
- 1973-11-15 GB GB5309673A patent/GB1429068A/en not_active Expired
- 1973-11-16 JP JP12840373A patent/JPS5732058B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES420359A1 (es) | 1976-04-01 |
| JPS49133379A (enrdf_load_stackoverflow) | 1974-12-21 |
| FR2206942B1 (enrdf_load_stackoverflow) | 1977-01-28 |
| NL7315294A (enrdf_load_stackoverflow) | 1974-05-20 |
| DE2356017A1 (de) | 1974-06-06 |
| IE38516L (en) | 1974-05-16 |
| DK137898B (da) | 1978-05-29 |
| IE38516B1 (en) | 1978-03-29 |
| AR204160A1 (es) | 1975-11-28 |
| CA976553A (en) | 1975-10-21 |
| FI55652C (fi) | 1979-09-10 |
| ZA737973B (en) | 1974-10-30 |
| FI55652B (fi) | 1979-05-31 |
| FR2206942A1 (enrdf_load_stackoverflow) | 1974-06-14 |
| JPS5732058B2 (enrdf_load_stackoverflow) | 1982-07-08 |
| CH586679A5 (enrdf_load_stackoverflow) | 1977-04-15 |
| GB1429068A (en) | 1976-03-24 |
| BE806228A (fr) | 1974-02-15 |
| DK137898C (enrdf_load_stackoverflow) | 1978-11-20 |
| ATA938573A (de) | 1976-03-15 |
| SE373850B (enrdf_load_stackoverflow) | 1975-02-17 |
| AT333278B (de) | 1976-11-10 |
| AU6216573A (en) | 1975-05-08 |
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