GB1429068A - Compounds useful as antidepressive agents and a process for their preparation - Google Patents

Compounds useful as antidepressive agents and a process for their preparation

Info

Publication number
GB1429068A
GB1429068A GB5309673A GB5309673A GB1429068A GB 1429068 A GB1429068 A GB 1429068A GB 5309673 A GB5309673 A GB 5309673A GB 5309673 A GB5309673 A GB 5309673A GB 1429068 A GB1429068 A GB 1429068A
Authority
GB
United Kingdom
Prior art keywords
compound
preparation
compounds useful
formula
nov
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5309673A
Inventor
P B Berntsson
P A E Carlsson
H R Corrodi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Publication of GB1429068A publication Critical patent/GB1429068A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters

Abstract

1429068 3-Mono- or di - bromophenyl - 3- (3 - pyridyl) - 1 - (dimethylamino) - propanes HASSLE AB 15 Nov 1973 [16 Nov 1972] 53096/73 Heading C2C Novel compounds of Formula VII wherein R<SP>1</SP> is H or Br and salts thereof are prepared by reaction of dimethylamine with a compound of Formula IX: which is obtained by hydrogenation of a compound of Formula VIII: Pharmaceutical compositions in conventional forms for oral, rectal or parenteral administration and having anti-depressant activity comprise an above novel compound and a carrier or diluent.
GB5309673A 1972-11-16 1973-11-15 Compounds useful as antidepressive agents and a process for their preparation Expired GB1429068A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7214872A SE373850B (en) 1972-11-16 1972-11-16

Publications (1)

Publication Number Publication Date
GB1429068A true GB1429068A (en) 1976-03-24

Family

ID=20299803

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5309673A Expired GB1429068A (en) 1972-11-16 1973-11-15 Compounds useful as antidepressive agents and a process for their preparation

Country Status (17)

Country Link
JP (1) JPS5732058B2 (en)
AR (1) AR204160A1 (en)
AT (1) AT333278B (en)
BE (1) BE806228A (en)
CA (1) CA976553A (en)
CH (1) CH586679A5 (en)
DE (1) DE2356017A1 (en)
DK (1) DK137898B (en)
ES (1) ES420359A1 (en)
FI (1) FI55652C (en)
FR (1) FR2206942B1 (en)
GB (1) GB1429068A (en)
IE (1) IE38516B1 (en)
NL (1) NL7315294A (en)
SE (1) SE373850B (en)
SU (1) SU482945A3 (en)
ZA (1) ZA737973B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418065A (en) 1979-11-16 1983-11-29 Astra Lakemedel Aktiebolag Halophenyl-pyridyl-allylamine derivatives and use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418065A (en) 1979-11-16 1983-11-29 Astra Lakemedel Aktiebolag Halophenyl-pyridyl-allylamine derivatives and use

Also Published As

Publication number Publication date
AT333278B (en) 1976-11-10
FI55652B (en) 1979-05-31
FR2206942A1 (en) 1974-06-14
SU482945A3 (en) 1975-08-30
DE2356017A1 (en) 1974-06-06
CH586679A5 (en) 1977-04-15
DK137898B (en) 1978-05-29
AU6216573A (en) 1975-05-08
IE38516L (en) 1974-05-16
ZA737973B (en) 1974-10-30
JPS5732058B2 (en) 1982-07-08
IE38516B1 (en) 1978-03-29
AR204160A1 (en) 1975-11-28
CA976553A (en) 1975-10-21
ATA938573A (en) 1976-03-15
JPS49133379A (en) 1974-12-21
FI55652C (en) 1979-09-10
NL7315294A (en) 1974-05-20
FR2206942B1 (en) 1977-01-28
DK137898C (en) 1978-11-20
ES420359A1 (en) 1976-04-01
SE373850B (en) 1975-02-17
BE806228A (en) 1974-02-15

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Legal Events

Date Code Title Description
PS Patent sealed
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee