IE38516B1 - Compounds useful as antidepressive agents and a process for their preparation - Google Patents

Compounds useful as antidepressive agents and a process for their preparation

Info

Publication number
IE38516B1
IE38516B1 IE2067/73A IE206773A IE38516B1 IE 38516 B1 IE38516 B1 IE 38516B1 IE 2067/73 A IE2067/73 A IE 2067/73A IE 206773 A IE206773 A IE 206773A IE 38516 B1 IE38516 B1 IE 38516B1
Authority
IE
Ireland
Prior art keywords
compound
preparation
compounds useful
formula
nov
Prior art date
Application number
IE2067/73A
Other versions
IE38516L (en
Inventor
P B Berntsson
P A E Carlsson
H R Corrodi
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of IE38516L publication Critical patent/IE38516L/en
Publication of IE38516B1 publication Critical patent/IE38516B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1429068 3-Mono- or di - bromophenyl - 3- (3 - pyridyl) - 1 - (dimethylamino) - propanes HASSLE AB 15 Nov 1973 [16 Nov 1972] 53096/73 Heading C2C Novel compounds of Formula VII wherein R<SP>1</SP> is H or Br and salts thereof are prepared by reaction of dimethylamine with a compound of Formula IX: which is obtained by hydrogenation of a compound of Formula VIII: Pharmaceutical compositions in conventional forms for oral, rectal or parenteral administration and having anti-depressant activity comprise an above novel compound and a carrier or diluent. [GB1429068A]
IE2067/73A 1972-11-16 1973-11-15 Compounds useful as antidepressive agents and a process for their preparation IE38516B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7214872A SE373850B (en) 1972-11-16 1972-11-16

Publications (2)

Publication Number Publication Date
IE38516L IE38516L (en) 1974-05-16
IE38516B1 true IE38516B1 (en) 1978-03-29

Family

ID=20299803

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2067/73A IE38516B1 (en) 1972-11-16 1973-11-15 Compounds useful as antidepressive agents and a process for their preparation

Country Status (17)

Country Link
JP (1) JPS5732058B2 (en)
AR (1) AR204160A1 (en)
AT (1) AT333278B (en)
BE (1) BE806228A (en)
CA (1) CA976553A (en)
CH (1) CH586679A5 (en)
DE (1) DE2356017A1 (en)
DK (1) DK137898B (en)
ES (1) ES420359A1 (en)
FI (1) FI55652C (en)
FR (1) FR2206942B1 (en)
GB (1) GB1429068A (en)
IE (1) IE38516B1 (en)
NL (1) NL7315294A (en)
SE (1) SE373850B (en)
SU (1) SU482945A3 (en)
ZA (1) ZA737973B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7909514L (en) 1979-11-16 1981-05-17 Astra Laekemedel Ab NEW HALOPHENYL-PYRIDYL-ALLYLAMINE DERIVATIVES

Also Published As

Publication number Publication date
DK137898C (en) 1978-11-20
CA976553A (en) 1975-10-21
GB1429068A (en) 1976-03-24
FR2206942A1 (en) 1974-06-14
FR2206942B1 (en) 1977-01-28
FI55652C (en) 1979-09-10
DK137898B (en) 1978-05-29
AT333278B (en) 1976-11-10
CH586679A5 (en) 1977-04-15
JPS5732058B2 (en) 1982-07-08
AR204160A1 (en) 1975-11-28
AU6216573A (en) 1975-05-08
NL7315294A (en) 1974-05-20
ATA938573A (en) 1976-03-15
BE806228A (en) 1974-02-15
FI55652B (en) 1979-05-31
DE2356017A1 (en) 1974-06-06
IE38516L (en) 1974-05-16
ES420359A1 (en) 1976-04-01
JPS49133379A (en) 1974-12-21
ZA737973B (en) 1974-10-30
SE373850B (en) 1975-02-17
SU482945A3 (en) 1975-08-30

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