SK9702003A3 - 3,7-Diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias - Google Patents
3,7-Diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias Download PDFInfo
- Publication number
- SK9702003A3 SK9702003A3 SK970-2003A SK9702003A SK9702003A3 SK 9702003 A3 SK9702003 A3 SK 9702003A3 SK 9702003 A SK9702003 A SK 9702003A SK 9702003 A3 SK9702003 A3 SK 9702003A3
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- Slovakia
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- group
- compound
- carbon atoms
- alkyl
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- 206010003119 arrhythmia Diseases 0.000 title claims abstract description 25
- 238000011282 treatment Methods 0.000 title claims abstract description 19
- QFCMBRXRVQRSSF-UHFFFAOYSA-N 1,2,3,3a,4,5,6,6a-octahydropyrrolo[3,4-c]pyrrole Chemical class C1NCC2CNCC21 QFCMBRXRVQRSSF-UHFFFAOYSA-N 0.000 title claims description 6
- 150000001875 compounds Chemical class 0.000 claims abstract description 401
- 230000006793 arrhythmia Effects 0.000 claims abstract description 14
- 230000001746 atrial effect Effects 0.000 claims abstract description 5
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- 206010003130 Arrhythmia supraventricular Diseases 0.000 claims abstract description 3
- 238000011321 prophylaxis Methods 0.000 claims abstract 5
- 125000004432 carbon atom Chemical group C* 0.000 claims description 205
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- 125000004122 cyclic group Chemical group 0.000 claims description 21
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- TWPUPYDZIUZHII-UHFFFAOYSA-N 5-benzyl-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole Chemical compound C1C2CN(C)CC2CN1CC1=CC=CC=C1 TWPUPYDZIUZHII-UHFFFAOYSA-N 0.000 claims description 2
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- 238000004519 manufacturing process Methods 0.000 claims 1
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- 125000001981 tert-butyldimethylsilyl group Chemical group [H]C([H])([H])[Si]([H])(C([H])([H])[H])[*]C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000000037 tert-butyldiphenylsilyl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1[Si]([H])([*]C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0100326A SE0100326D0 (sv) | 2001-02-02 | 2001-02-02 | New compounds |
| PCT/SE2002/000152 WO2002060902A1 (en) | 2001-02-02 | 2002-01-29 | 3,7-diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK9702003A3 true SK9702003A3 (en) | 2004-01-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK970-2003A SK9702003A3 (en) | 2001-02-02 | 2002-01-29 | 3,7-Diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US7144914B2 (cs) |
| EP (1) | EP1360187B1 (cs) |
| JP (1) | JP2004522749A (cs) |
| KR (1) | KR20030074764A (cs) |
| CN (2) | CN1854138A (cs) |
| AR (1) | AR035423A1 (cs) |
| AT (1) | ATE298339T1 (cs) |
| BG (1) | BG108035A (cs) |
| BR (1) | BR0206791A (cs) |
| CA (1) | CA2434970A1 (cs) |
| CZ (1) | CZ20032061A3 (cs) |
| DE (1) | DE60204755T2 (cs) |
| EE (1) | EE200300364A (cs) |
| ES (1) | ES2243706T3 (cs) |
| HU (1) | HUP0302538A3 (cs) |
| IL (1) | IL156734A0 (cs) |
| IS (1) | IS6874A (cs) |
| MX (1) | MXPA03006579A (cs) |
| MY (1) | MY136788A (cs) |
| NO (1) | NO20033434L (cs) |
| NZ (1) | NZ526992A (cs) |
| PL (1) | PL363454A1 (cs) |
| PT (1) | PT1360187E (cs) |
| RU (1) | RU2293085C2 (cs) |
| SE (1) | SE0100326D0 (cs) |
| SK (1) | SK9702003A3 (cs) |
| UA (1) | UA75382C2 (cs) |
| WO (1) | WO2002060902A1 (cs) |
| ZA (1) | ZA200305345B (cs) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002070523A1 (en) * | 2001-03-07 | 2002-09-12 | Pfizer Products Inc. | Modulators of chemokine receptor activity |
| PL1761542T3 (pl) * | 2004-06-09 | 2008-06-30 | Hoffmann La Roche | Pochodne oktahydropirolo[3,4-c]pirolu i ich zastosowanie jako środków przeciwwirusowych |
| US7665658B2 (en) | 2005-06-07 | 2010-02-23 | First Data Corporation | Dynamic aggregation of payment transactions |
| GB0514018D0 (en) * | 2005-07-07 | 2005-08-17 | Ionix Pharmaceuticals Ltd | Chemical compounds |
| US8653263B2 (en) | 2009-10-23 | 2014-02-18 | Janssen Pharmaceutica | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
| CN102718695B (zh) * | 2012-06-25 | 2014-04-02 | 华东师范大学 | 一种氮杂双环[3.3.0]辛烷衍生物的合成方法 |
| MX379228B (es) | 2013-03-15 | 2025-03-10 | Global Blood Therapeutics Inc | Compuestos y usos de estos para la modulación de la hemoglobina. |
| CA2917050A1 (en) * | 2013-07-03 | 2015-01-08 | Todd K. Jones | Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof |
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