EE200300364A - 3,7-diasabitsüklo[3,3,0]oktaanid ja nende kasutamine südame arütmiate ravis - Google Patents

3,7-diasabitsüklo[3,3,0]oktaanid ja nende kasutamine südame arütmiate ravis

Info

Publication number
EE200300364A
EE200300364A EEP200300364A EEP200300364A EE200300364A EE 200300364 A EE200300364 A EE 200300364A EE P200300364 A EEP200300364 A EE P200300364A EE P200300364 A EEP200300364 A EE P200300364A EE 200300364 A EE200300364 A EE 200300364A
Authority
EE
Estonia
Prior art keywords
octanes
diazabicyclo
treatment
cardiac arrhythmias
arrhythmias
Prior art date
Application number
EEP200300364A
Other languages
English (en)
Inventor
Bj�rsne Magnus
Pont�n Fritiof
Strandlund Gert
Svensson Peder
Wilstermann Michael
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200300364A publication Critical patent/EE200300364A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200300364A 2001-02-02 2002-01-29 3,7-diasabitsüklo[3,3,0]oktaanid ja nende kasutamine südame arütmiate ravis EE200300364A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0100326A SE0100326D0 (sv) 2001-02-02 2001-02-02 New compounds
PCT/SE2002/000152 WO2002060902A1 (en) 2001-02-02 2002-01-29 3,7-diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
EE200300364A true EE200300364A (et) 2003-10-15

Family

ID=20282824

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300364A EE200300364A (et) 2001-02-02 2002-01-29 3,7-diasabitsüklo[3,3,0]oktaanid ja nende kasutamine südame arütmiate ravis

Country Status (30)

Country Link
US (1) US7144914B2 (et)
EP (1) EP1360187B1 (et)
JP (1) JP2004522749A (et)
KR (1) KR20030074764A (et)
CN (2) CN1854138A (et)
AR (1) AR035423A1 (et)
AT (1) ATE298339T1 (et)
BG (1) BG108035A (et)
BR (1) BR0206791A (et)
CA (1) CA2434970A1 (et)
CZ (1) CZ20032061A3 (et)
DE (1) DE60204755T2 (et)
EE (1) EE200300364A (et)
ES (1) ES2243706T3 (et)
HK (1) HK1063629A1 (et)
HU (1) HUP0302538A3 (et)
IL (1) IL156734A0 (et)
IS (1) IS6874A (et)
MX (1) MXPA03006579A (et)
MY (1) MY136788A (et)
NO (1) NO20033434L (et)
NZ (1) NZ526992A (et)
PL (1) PL363454A1 (et)
PT (1) PT1360187E (et)
RU (1) RU2293085C2 (et)
SE (1) SE0100326D0 (et)
SK (1) SK9702003A3 (et)
UA (1) UA75382C2 (et)
WO (1) WO2002060902A1 (et)
ZA (1) ZA200305345B (et)

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CA2440803A1 (en) * 2001-03-07 2002-09-12 Pfizer Products Inc. Modulators of chemokine receptor activity
CN101001860A (zh) * 2004-06-09 2007-07-18 霍夫曼-拉罗奇有限公司 杂环抗病毒化合物
US7665658B2 (en) 2005-06-07 2010-02-23 First Data Corporation Dynamic aggregation of payment transactions
GB0514018D0 (en) * 2005-07-07 2005-08-17 Ionix Pharmaceuticals Ltd Chemical compounds
JP5759470B2 (ja) 2009-10-23 2015-08-05 ヤンセン ファーマシューティカ エヌ．ベー． オレキシン受容体調節因子としての二置換オクタヒドロピロロ［３，４−ｃ］ピロール
CN102718695B (zh) * 2012-06-25 2014-04-02 华东师范大学 一种氮杂双环[3.3.0]辛烷衍生物的合成方法
CN112500338A (zh) 2013-03-15 2021-03-16 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
WO2015003002A1 (en) * 2013-07-03 2015-01-08 Abide Therapeutics, Inc. Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
KR102559922B1 (ko) 2016-03-10 2023-07-25 얀센 파마슈티카 엔.브이. 오렉신-2 수용체 길항제를 사용한 우울증의 치료 방법
KR20190015492A (ko) 2016-06-08 2019-02-13 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 화학적 화합물
RS60209B1 (sr) 2017-03-20 2020-06-30 Forma Therapeutics Inc Kompozicije pirolopirola kao aktivatori piruvat kinaze (pkr)
WO2020061255A1 (en) 2018-09-19 2020-03-26 Forma Therapeutics, Inc. Activating pyruvate kinase r
US20220031671A1 (en) 2018-09-19 2022-02-03 Forma Therapeutics, Inc. Treating sickle cell disease with a pyruvate kinase r activating compound
RU2726120C1 (ru) * 2019-09-24 2020-07-09 Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук N-алкил-n-{ [3-алкил-3,8-диазабицикло[3.2.1]окта-1(7),5-диен-8-ил]метил} амины, обладающие цитотоксической активностью в отношении клеточной линии нек 293

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DE2428792A1 (de) * 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) * 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
DE3930266A1 (de) 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4338396A1 (de) 1993-11-10 1995-05-11 Basf Ag N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4341403A1 (de) 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
US5457121A (en) * 1994-09-02 1995-10-10 Eli Lilly And Company Cis-hexahydro-5-(1,2,3,4-tetrahydro-2-naphthalenyl)pyrrolo<3,4-c>pyrroles as inhibitors of serotonin reuptake
DE59610771D1 (de) * 1995-02-27 2003-11-20 Hoffmann La Roche Dioxopyrrolo-pyrrolderivate
AU702752B2 (en) 1995-05-11 1999-03-04 Pharmacia & Upjohn Company Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones
JPH11510478A (ja) * 1995-06-06 1999-09-14 アボツト・ラボラトリーズ キノリジノン型化合物
ES2214546T3 (es) 1995-09-15 2004-09-16 PHARMACIA &amp; UPJOHN COMPANY N-oxidos de aminoariloxazolidinona.
GB9519563D0 (en) * 1995-09-26 1995-11-29 Merck Sharp & Dohme Therapeutic agents
ATE228137T1 (de) 1996-08-13 2002-12-15 Merck & Co Inc Palladiumkatalysierte indolisierung
US5808064A (en) * 1996-08-13 1998-09-15 Merck & Co., Inc. Palladium catalyzed indolization
SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
US6355641B1 (en) * 1999-03-17 2002-03-12 Syntex (U.S.A.) Llc Oxazolone derivatives and uses thereof
DE19932621A1 (de) * 1999-07-13 2001-04-26 Bayer Ag Neue substituerte alpha, beta-anellierte Butyrolactone
MY137020A (en) * 2000-04-27 2008-12-31 Abbott Lab Diazabicyclic central nervous system active agents
WO2002044168A2 (en) * 2000-11-20 2002-06-06 Scios Inc. Indole-type inhibitors of p38 kinase

Also Published As

Publication number Publication date
AR035423A1 (es) 2004-05-26
EP1360187B1 (en) 2005-06-22
HK1063629A1 (en) 2005-01-07
NO20033434L (no) 2003-09-23
SE0100326D0 (sv) 2001-02-02
BG108035A (bg) 2003-07-28
PT1360187E (pt) 2005-10-31
KR20030074764A (ko) 2003-09-19
US7144914B2 (en) 2006-12-05
WO2002060902A1 (en) 2002-08-08
HUP0302538A2 (hu) 2003-11-28
CA2434970A1 (en) 2002-08-08
CZ20032061A3 (cs) 2003-10-15
HUP0302538A3 (en) 2006-05-29
MY136788A (en) 2008-11-28
DE60204755D1 (de) 2005-07-28
IS6874A (is) 2004-07-11
PL363454A1 (en) 2004-11-15
ES2243706T3 (es) 2005-12-01
ZA200305345B (en) 2004-10-11
CN1489592A (zh) 2004-04-14
CN1263758C (zh) 2006-07-12
IL156734A0 (en) 2004-02-08
SK9702003A3 (en) 2004-01-08
US20040053986A1 (en) 2004-03-18
ATE298339T1 (de) 2005-07-15
UA75382C2 (en) 2006-04-17
CN1854138A (zh) 2006-11-01
RU2003121308A (ru) 2005-03-10
BR0206791A (pt) 2004-01-27
NO20033434D0 (no) 2003-08-01
JP2004522749A (ja) 2004-07-29
RU2293085C2 (ru) 2007-02-10
DE60204755T2 (de) 2006-05-18
NZ526992A (en) 2005-01-28
EP1360187A1 (en) 2003-11-12
MXPA03006579A (es) 2003-09-22

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