AU2001296173A1 - 3,8-diazabicyclo(3.2.1)octanes and their use in the treatment of cardiac arrhythmias - Google Patents

3,8-diazabicyclo(3.2.1)octanes and their use in the treatment of cardiac arrhythmias

Info

Publication number
AU2001296173A1
AU2001296173A1 AU2001296173A AU9617301A AU2001296173A1 AU 2001296173 A1 AU2001296173 A1 AU 2001296173A1 AU 2001296173 A AU2001296173 A AU 2001296173A AU 9617301 A AU9617301 A AU 9617301A AU 2001296173 A1 AU2001296173 A1 AU 2001296173A1
Authority
AU
Australia
Prior art keywords
octanes
diazabicyclo
treatment
cardiac arrhythmias
arrhythmias
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001296173A
Inventor
Magnus Bjorsne
Kurt-Jurgen Hoffmann
Fritiof Ponten
Gert Strandlund
Peder Svensson
Michael Wilstermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of AU2001296173A1 publication Critical patent/AU2001296173A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
AU2001296173A 2000-10-20 2001-10-18 3,8-diazabicyclo(3.2.1)octanes and their use in the treatment of cardiac arrhythmias Abandoned AU2001296173A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0003795 2000-10-20
SE0003795A SE0003795D0 (en) 2000-10-20 2000-10-20 Pharmaceutically useful compounds
PCT/SE2001/002294 WO2002032902A1 (en) 2000-10-20 2001-10-18 3,8-diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
AU2001296173A1 true AU2001296173A1 (en) 2002-04-29

Family

ID=20281488

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001296173A Abandoned AU2001296173A1 (en) 2000-10-20 2001-10-18 3,8-diazabicyclo(3.2.1)octanes and their use in the treatment of cardiac arrhythmias

Country Status (6)

Country Link
US (1) US7012074B2 (en)
EP (1) EP1328526A1 (en)
JP (1) JP2004511559A (en)
AU (1) AU2001296173A1 (en)
SE (1) SE0003795D0 (en)
WO (1) WO2002032902A1 (en)

Families Citing this family (8)

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EP1406898B1 (en) * 2001-07-19 2005-04-06 Cv Therapeutics, Inc. Substituted piperazine compounds and their use as fatty acid oxidation inhibitors
DE60314662T2 (en) * 2002-12-05 2008-03-13 CV Therapeutics, Inc., Palo Alto SUBSTITUTED PIPERAZIN COMPOUNDS AND THEIR USE AS FATTY ACIDATION INHIBITORS
DE60329323D1 (en) * 2003-01-03 2009-10-29 Cv Therapeutics Inc Substituted heterocyclic compounds
JP2006515891A (en) * 2003-01-17 2006-06-08 シーブイ・セラピューティクス・インコーポレイテッド Substituted heterocyclic compounds effective for the treatment of cardiovascular diseases
US7208496B2 (en) * 2003-06-23 2007-04-24 Cv Therapeutics, Inc. Substituted heterocyclic compounds
US8673920B2 (en) * 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
CN107383025B (en) * 2017-06-30 2019-04-26 吉林凯莱英医药化学有限公司 The preparation method of endocyclic compound
CN111892599B (en) * 2020-08-14 2023-01-13 黄芳 Synthesis method of 2,5-diazabicyclo [2.2.2] octane-2-tert-butyl carboxylate

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IT1271350B (en) 1993-01-29 1997-05-27 Riace Establischment DERIVATIVES OF 3.8 DIAZABICICLO (3,2,1) - OCTAN AS CENTRAL ANALGESIC MEDICATIONS
TW301607B (en) 1993-03-09 1997-04-01 Takeda Pharm Industry Co Ltd
TW273551B (en) 1993-05-24 1996-04-01 Wakiei Seiyaku Kk
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
US5854239A (en) 1993-12-29 1998-12-29 Pfizer Inc. Diazabicyclic neuokinin antagonists
DE4402931A1 (en) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh New drugs containing 3-phenylsulfonyl-3,7-diazabicyclo [3,3,1] nonane compounds
IT1274018B (en) 1994-02-23 1997-07-14 Riace Ets 3,8-DIAZABICYCLE DERIVATIVES (3.2.1.) OCTANO FOR ANALGESIC ACTIVITY
EP0804425A2 (en) 1994-07-29 1997-11-05 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
GB2295387A (en) 1994-11-23 1996-05-29 Glaxo Inc Quinazoline antagonists of alpha 1c adrenergic receptors
CA2218503C (en) 1995-04-20 2001-07-24 Pfizer Inc. Arylsulfonyl hydroxamic acid derivatives
FR2733984B1 (en) 1995-05-10 1997-07-04 Rhone Poulenc Rorer Sa TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
PT825186E (en) 1996-08-16 2002-08-30 Pfizer 2-AMINOBENZAZEPINE DERIVATIVES AND THEIR USE FOR IMMUNOSUPPRESSION TREATMENT
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Also Published As

Publication number Publication date
US7012074B2 (en) 2006-03-14
WO2002032902A1 (en) 2002-04-25
EP1328526A1 (en) 2003-07-23
SE0003795D0 (en) 2000-10-20
US20040023971A1 (en) 2004-02-05
JP2004511559A (en) 2004-04-15

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