NO20033434L - 3,7-diazabicyklo(3.3.0)oktaner og anvendelse derav ved behandling av hjertearrytmier - Google Patents

3,7-diazabicyklo(3.3.0)oktaner og anvendelse derav ved behandling av hjertearrytmier

Info

Publication number
NO20033434L
NO20033434L NO20033434A NO20033434A NO20033434L NO 20033434 L NO20033434 L NO 20033434L NO 20033434 A NO20033434 A NO 20033434A NO 20033434 A NO20033434 A NO 20033434A NO 20033434 L NO20033434 L NO 20033434L
Authority
NO
Norway
Prior art keywords
octanes
diazabicyclo
treatment
cardiac arrhythmias
arrhythmias
Prior art date
Application number
NO20033434A
Other languages
English (en)
Other versions
NO20033434D0 (no
Inventor
Magnus Bjoersne
Michael Wilstermann
Fritiof Ponten
Gert Strandlund
Peder Svensson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20033434D0 publication Critical patent/NO20033434D0/no
Publication of NO20033434L publication Critical patent/NO20033434L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
NO20033434A 2001-02-02 2003-08-01 3,7-diazabicyklo(3.3.0)oktaner og anvendelse derav ved behandling av hjertearrytmier NO20033434L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0100326A SE0100326D0 (sv) 2001-02-02 2001-02-02 New compounds
PCT/SE2002/000152 WO2002060902A1 (en) 2001-02-02 2002-01-29 3,7-diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias

Publications (2)

Publication Number Publication Date
NO20033434D0 NO20033434D0 (no) 2003-08-01
NO20033434L true NO20033434L (no) 2003-09-23

Family

ID=20282824

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20033434A NO20033434L (no) 2001-02-02 2003-08-01 3,7-diazabicyklo(3.3.0)oktaner og anvendelse derav ved behandling av hjertearrytmier

Country Status (30)

Country Link
US (1) US7144914B2 (no)
EP (1) EP1360187B1 (no)
JP (1) JP2004522749A (no)
KR (1) KR20030074764A (no)
CN (2) CN1854138A (no)
AR (1) AR035423A1 (no)
AT (1) ATE298339T1 (no)
BG (1) BG108035A (no)
BR (1) BR0206791A (no)
CA (1) CA2434970A1 (no)
CZ (1) CZ20032061A3 (no)
DE (1) DE60204755T2 (no)
EE (1) EE200300364A (no)
ES (1) ES2243706T3 (no)
HK (1) HK1063629A1 (no)
HU (1) HUP0302538A3 (no)
IL (1) IL156734A0 (no)
IS (1) IS6874A (no)
MX (1) MXPA03006579A (no)
MY (1) MY136788A (no)
NO (1) NO20033434L (no)
NZ (1) NZ526992A (no)
PL (1) PL363454A1 (no)
PT (1) PT1360187E (no)
RU (1) RU2293085C2 (no)
SE (1) SE0100326D0 (no)
SK (1) SK9702003A3 (no)
UA (1) UA75382C2 (no)
WO (1) WO2002060902A1 (no)
ZA (1) ZA200305345B (no)

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ES2297727T3 (es) * 2004-06-09 2008-05-01 F. Hoffmann-La Roche Ag Derivados de octahidropirrolo(3,4-c)pirrol y su empleo como agentes antiviricos.
US7665658B2 (en) 2005-06-07 2010-02-23 First Data Corporation Dynamic aggregation of payment transactions
GB0514018D0 (en) * 2005-07-07 2005-08-17 Ionix Pharmaceuticals Ltd Chemical compounds
JP5759470B2 (ja) 2009-10-23 2015-08-05 ヤンセン ファーマシューティカ エヌ.ベー. オレキシン受容体調節因子としての二置換オクタヒドロピロロ[3,4−c]ピロール
CN102718695B (zh) * 2012-06-25 2014-04-02 华东师范大学 一种氮杂双环[3.3.0]辛烷衍生物的合成方法
CN105073728A (zh) 2013-03-15 2015-11-18 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
WO2015003002A1 (en) * 2013-07-03 2015-01-08 Abide Therapeutics, Inc. Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
HRP20220642T1 (hr) 2016-03-10 2022-06-24 Janssen Pharmaceutica Nv Postupci za liječenje depresije uporabom antagonista receptora oreksina 2
CN109563034A (zh) 2016-06-08 2019-04-02 葛兰素史密斯克莱知识产权发展有限公司 化学化合物
CN109311897B (zh) 2017-03-20 2021-07-20 福马治疗股份有限公司 作为丙酮酸激酶(pkr)活化剂的吡咯并吡咯组合物
US20230055923A1 (en) 2018-09-19 2023-02-23 Forma Therapeutics, Inc. Activating pyruvate kinase r
US20200129485A1 (en) 2018-09-19 2020-04-30 Forma Therapeutics, Inc. Treating sickle cell disease with a pyruvate kinase r activating compound
RU2726120C1 (ru) * 2019-09-24 2020-07-09 Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук N-алкил-n-{ [3-алкил-3,8-диазабицикло[3.2.1]окта-1(7),5-диен-8-ил]метил} амины, обладающие цитотоксической активностью в отношении клеточной линии нек 293

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DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
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DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4338396A1 (de) 1993-11-10 1995-05-11 Basf Ag N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
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US5457121A (en) 1994-09-02 1995-10-10 Eli Lilly And Company Cis-hexahydro-5-(1,2,3,4-tetrahydro-2-naphthalenyl)pyrrolo<3,4-c>pyrroles as inhibitors of serotonin reuptake
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SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
US6355641B1 (en) * 1999-03-17 2002-03-12 Syntex (U.S.A.) Llc Oxazolone derivatives and uses thereof
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MY145722A (en) * 2000-04-27 2012-03-30 Abbott Lab Diazabicyclic central nervous system active agents
CA2429382A1 (en) * 2000-11-20 2002-06-06 Scios Inc. Indole-type inhibitors of p38 kinase

Also Published As

Publication number Publication date
EP1360187A1 (en) 2003-11-12
MXPA03006579A (es) 2003-09-22
WO2002060902A1 (en) 2002-08-08
EP1360187B1 (en) 2005-06-22
HK1063629A1 (en) 2005-01-07
AR035423A1 (es) 2004-05-26
UA75382C2 (en) 2006-04-17
CA2434970A1 (en) 2002-08-08
DE60204755D1 (de) 2005-07-28
HUP0302538A3 (en) 2006-05-29
SE0100326D0 (sv) 2001-02-02
HUP0302538A2 (hu) 2003-11-28
JP2004522749A (ja) 2004-07-29
DE60204755T2 (de) 2006-05-18
SK9702003A3 (en) 2004-01-08
BR0206791A (pt) 2004-01-27
US20040053986A1 (en) 2004-03-18
ATE298339T1 (de) 2005-07-15
NZ526992A (en) 2005-01-28
BG108035A (bg) 2003-07-28
RU2003121308A (ru) 2005-03-10
KR20030074764A (ko) 2003-09-19
CN1489592A (zh) 2004-04-14
ZA200305345B (en) 2004-10-11
IL156734A0 (en) 2004-02-08
EE200300364A (et) 2003-10-15
US7144914B2 (en) 2006-12-05
PL363454A1 (en) 2004-11-15
ES2243706T3 (es) 2005-12-01
CZ20032061A3 (cs) 2003-10-15
IS6874A (is) 2004-07-11
MY136788A (en) 2008-11-28
NO20033434D0 (no) 2003-08-01
PT1360187E (pt) 2005-10-31
RU2293085C2 (ru) 2007-02-10
CN1263758C (zh) 2006-07-12
CN1854138A (zh) 2006-11-01

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