HK1045690A1 - 用於治療心臟心律失常的新的橋合二哌啶化合物 - Google Patents

用於治療心臟心律失常的新的橋合二哌啶化合物

Info

Publication number
HK1045690A1
HK1045690A1 HK02107115.3A HK02107115A HK1045690A1 HK 1045690 A1 HK1045690 A1 HK 1045690A1 HK 02107115 A HK02107115 A HK 02107115A HK 1045690 A1 HK1045690 A1 HK 1045690A1
Authority
HK
Hong Kong
Prior art keywords
treatment
compounds useful
cardiac arrhythmias
bispidine compounds
bispidine
Prior art date
Application number
HK02107115.3A
Other languages
English (en)
Inventor
Bjore Annika
Bjorsne Magnus
Halvarsson Torbjorn
Hoffmann Kurt-Jurgen
Samuelsson Bertil
Strandlund Gert
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1045690A1 publication Critical patent/HK1045690A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK02107115.3A 1999-06-16 2002-09-26 用於治療心臟心律失常的新的橋合二哌啶化合物 HK1045690A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9902270A SE9902270D0 (sv) 1999-06-16 1999-06-16 Pharmaceutically active compounds
PCT/SE2000/001253 WO2000076999A1 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
HK1045690A1 true HK1045690A1 (zh) 2002-12-06

Family

ID=20416102

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107115.3A HK1045690A1 (zh) 1999-06-16 2002-09-26 用於治療心臟心律失常的新的橋合二哌啶化合物

Country Status (29)

Country Link
US (1) US6887881B1 (zh)
EP (1) EP1192154B1 (zh)
JP (1) JP2003502328A (zh)
KR (1) KR20020010711A (zh)
CN (1) CN1187350C (zh)
AR (1) AR024393A1 (zh)
AT (1) ATE261965T1 (zh)
AU (1) AU762244B2 (zh)
BR (1) BR0011673A (zh)
CA (1) CA2384339A1 (zh)
CZ (1) CZ20014494A3 (zh)
DE (1) DE60009069T2 (zh)
DK (1) DK1192154T3 (zh)
EE (1) EE200100674A (zh)
ES (1) ES2216912T3 (zh)
HK (1) HK1045690A1 (zh)
HU (1) HUP0202929A3 (zh)
IL (1) IL146752A0 (zh)
IS (1) IS6199A (zh)
MX (1) MXPA01012925A (zh)
NO (1) NO20016127L (zh)
NZ (1) NZ516015A (zh)
PL (1) PL353794A1 (zh)
PT (1) PT1192154E (zh)
SE (1) SE9902270D0 (zh)
SK (1) SK18282001A3 (zh)
TR (1) TR200103659T2 (zh)
WO (1) WO2000076999A1 (zh)
ZA (1) ZA200109800B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
AR030302A1 (es) * 2000-07-07 2003-08-20 Astrazeneca Ab Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios
EP3052498A1 (en) 2013-09-30 2016-08-10 Council of Scientific & Industrial Research 3,7-diazabicyclo[3.3.1]nonane carboxamides as antithrombotic agents

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
ATA237287A (de) 1987-09-21 1993-02-15 Vaillant Gmbh Steuerung der temperatur des heizmediums einer umlaufheizung
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
US6200986B1 (en) 1995-11-13 2001-03-13 Smithkline Beecham Corporation Hemoregulatory compounds
SE9602263D0 (sv) * 1996-06-07 1996-06-07 Astra Ab New amino acid derivatives
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SE9803517D0 (sv) * 1998-10-15 1998-10-15 Astra Ab Pharmaceutical preparation
GB9823103D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
SK13422001A3 (sk) 1999-04-09 2002-05-09 Astrazeneca Ab Adamantánové deriváty
SE9901875D0 (sv) 1999-05-25 1999-05-25 Astra Pharma Prod Novel compounds
US20040229900A1 (en) * 1999-06-16 2004-11-18 Astrazeneca Ab Bispidine compounds useful in the treatment of cardiac arrythmias
SE9902271D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
SE0002603D0 (sv) * 2000-07-07 2000-07-07 Astrazeneca Ab New compounds

Also Published As

Publication number Publication date
NO20016127D0 (no) 2001-12-14
CN1370164A (zh) 2002-09-18
EP1192154A1 (en) 2002-04-03
US6887881B1 (en) 2005-05-03
NO20016127L (no) 2002-02-12
EP1192154B1 (en) 2004-03-17
AU5861100A (en) 2001-01-02
AR024393A1 (es) 2002-10-02
PL353794A1 (en) 2003-12-01
ATE261965T1 (de) 2004-04-15
DE60009069D1 (de) 2004-04-22
CZ20014494A3 (cs) 2002-05-15
HUP0202929A2 (hu) 2003-02-28
ZA200109800B (en) 2003-02-28
BR0011673A (pt) 2002-03-12
SE9902270D0 (sv) 1999-06-16
IS6199A (is) 2001-12-14
WO2000076999A1 (en) 2000-12-21
MXPA01012925A (es) 2002-07-30
KR20020010711A (ko) 2002-02-04
JP2003502328A (ja) 2003-01-21
TR200103659T2 (tr) 2002-04-22
EE200100674A (et) 2003-02-17
AU762244B2 (en) 2003-06-19
NZ516015A (en) 2003-06-30
CN1187350C (zh) 2005-02-02
PT1192154E (pt) 2004-07-30
HUP0202929A3 (en) 2003-04-28
DK1192154T3 (da) 2004-06-28
SK18282001A3 (sk) 2002-12-03
ES2216912T3 (es) 2004-11-01
IL146752A0 (en) 2002-07-25
DE60009069T2 (de) 2004-10-14
CA2384339A1 (en) 2000-12-21

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