AR024393A1 - Nuevos compuestos de bispidina para usar en el tratamiento de las arritmias cardiacas. - Google Patents

Nuevos compuestos de bispidina para usar en el tratamiento de las arritmias cardiacas.

Info

Publication number
AR024393A1
AR024393A1 ARP000103017A ARP000103017A AR024393A1 AR 024393 A1 AR024393 A1 AR 024393A1 AR P000103017 A ARP000103017 A AR P000103017A AR P000103017 A ARP000103017 A AR P000103017A AR 024393 A1 AR024393 A1 AR 024393A1
Authority
AR
Argentina
Prior art keywords
treatment
arritmias
cardiac
compounds
bispidine compounds
Prior art date
Application number
ARP000103017A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR024393A1 publication Critical patent/AR024393A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se presentan compuestos de la formula 1 en la cual R1, R2, R3, R4, R5a, R5b, R6, A, B y D tienen los significados expuestos en la memoria descriptiva, queson utiles para la profilaxis y el tratamiento de las arritmias, en especial las arritmias auriculares y ventriculares.
ARP000103017A 1999-06-16 2000-06-16 Nuevos compuestos de bispidina para usar en el tratamiento de las arritmias cardiacas. AR024393A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9902270A SE9902270D0 (sv) 1999-06-16 1999-06-16 Pharmaceutically active compounds

Publications (1)

Publication Number Publication Date
AR024393A1 true AR024393A1 (es) 2002-10-02

Family

ID=20416102

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000103017A AR024393A1 (es) 1999-06-16 2000-06-16 Nuevos compuestos de bispidina para usar en el tratamiento de las arritmias cardiacas.

Country Status (29)

Country Link
US (1) US6887881B1 (es)
EP (1) EP1192154B1 (es)
JP (1) JP2003502328A (es)
KR (1) KR20020010711A (es)
CN (1) CN1187350C (es)
AR (1) AR024393A1 (es)
AT (1) ATE261965T1 (es)
AU (1) AU762244B2 (es)
BR (1) BR0011673A (es)
CA (1) CA2384339A1 (es)
CZ (1) CZ20014494A3 (es)
DE (1) DE60009069T2 (es)
DK (1) DK1192154T3 (es)
EE (1) EE200100674A (es)
ES (1) ES2216912T3 (es)
HK (1) HK1045690A1 (es)
HU (1) HUP0202929A3 (es)
IL (1) IL146752A0 (es)
IS (1) IS6199A (es)
MX (1) MXPA01012925A (es)
NO (1) NO20016127L (es)
NZ (1) NZ516015A (es)
PL (1) PL353794A1 (es)
PT (1) PT1192154E (es)
SE (1) SE9902270D0 (es)
SK (1) SK18282001A3 (es)
TR (1) TR200103659T2 (es)
WO (1) WO2000076999A1 (es)
ZA (1) ZA200109800B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
AR030302A1 (es) * 2000-07-07 2003-08-20 Astrazeneca Ab Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios
US20160214983A1 (en) 2013-09-30 2016-07-28 Council Of Scientific & Industrial Research 3,7-diazabicyclo[3.3.1]nonane carboxamides as antithrombotic agents

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
ATA237287A (de) 1987-09-21 1993-02-15 Vaillant Gmbh Steuerung der temperatur des heizmediums einer umlaufheizung
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
WO1997017961A1 (en) 1995-11-13 1997-05-22 Smithkline Beecham Corporation Hemoregulatory compounds
SE9602263D0 (sv) * 1996-06-07 1996-06-07 Astra Ab New amino acid derivatives
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SE9803517D0 (sv) * 1998-10-15 1998-10-15 Astra Ab Pharmaceutical preparation
GB9823103D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
NZ514477A (en) 1999-04-09 2003-04-29 Astrazeneca Ab Adamantane derivatives
SE9901875D0 (sv) 1999-05-25 1999-05-25 Astra Pharma Prod Novel compounds
SE9902271D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
US20040229900A1 (en) * 1999-06-16 2004-11-18 Astrazeneca Ab Bispidine compounds useful in the treatment of cardiac arrythmias
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
SE0002603D0 (sv) * 2000-07-07 2000-07-07 Astrazeneca Ab New compounds

Also Published As

Publication number Publication date
EP1192154A1 (en) 2002-04-03
HK1045690A1 (zh) 2002-12-06
DK1192154T3 (da) 2004-06-28
PT1192154E (pt) 2004-07-30
TR200103659T2 (tr) 2002-04-22
CA2384339A1 (en) 2000-12-21
ES2216912T3 (es) 2004-11-01
CZ20014494A3 (cs) 2002-05-15
AU762244B2 (en) 2003-06-19
SK18282001A3 (sk) 2002-12-03
US6887881B1 (en) 2005-05-03
HUP0202929A3 (en) 2003-04-28
NZ516015A (en) 2003-06-30
IL146752A0 (en) 2002-07-25
HUP0202929A2 (hu) 2003-02-28
ATE261965T1 (de) 2004-04-15
NO20016127L (no) 2002-02-12
BR0011673A (pt) 2002-03-12
PL353794A1 (en) 2003-12-01
EE200100674A (et) 2003-02-17
ZA200109800B (en) 2003-02-28
WO2000076999A1 (en) 2000-12-21
CN1187350C (zh) 2005-02-02
IS6199A (is) 2001-12-14
MXPA01012925A (es) 2002-07-30
DE60009069T2 (de) 2004-10-14
AU5861100A (en) 2001-01-02
JP2003502328A (ja) 2003-01-21
SE9902270D0 (sv) 1999-06-16
NO20016127D0 (no) 2001-12-14
EP1192154B1 (en) 2004-03-17
KR20020010711A (ko) 2002-02-04
DE60009069D1 (de) 2004-04-22
CN1370164A (zh) 2002-09-18

Similar Documents

Publication Publication Date Title
CU23210A3 (es) NUEVOS COMPUESTOS DE OXABISPIDINE uTIL EN EL TRATAMIENTO DE ARRITMIAS CARDIACAS
EA200500853A1 (ru) 2,4,6-тризамещённые пиримидины, являющиеся ингибиторами фосфотидилинозитол(pi)-3-киназы, и их применение при лечении рака
ECSP044992A (es) Inhibidores de la alquín-aril fosfodiesterasa-4
BRPI0412348A (pt) derivados de piperazina e seu uso como agentes terapêuticos
UY26383A1 (es) "compuestos farmacéuticamente activos"
IL173032A0 (en) Pyridazine derivatives and their use as therapeutic agents
AR026925A1 (es) Nuevos derivados de azabiciclooctano utiles en el tratamiento de arritmias cardiacas
ATE332302T1 (de) Alkylierte imidazopyridinderivate
DE60115466D1 (de) Wirkstoffvorläufer von imidazopyridin-derivaten
SE0100326D0 (sv) New compounds
DE50101861D1 (de) Tocotrienolchinon- zyklisierungsprodukte mit antihypercholesterin wirkung
AR024393A1 (es) Nuevos compuestos de bispidina para usar en el tratamiento de las arritmias cardiacas.
UY27074A1 (es) Derivados de aminotriazolopiridina
DK34087D0 (da) Acyltripeptid-forbindelser og deres anvendelse som immunostimulanter
UA85232C2 (ru) Оксабиспидиновые соединения и их применение в лечении сердечных аритмий
AR024578A1 (es) Nuevos compuestos de bispidinas para usar en el tratamiento de las arritmias cardiacas
ECSP078025A (es) Nuevos compuestos de oxabispidina para el tratamiento de las arritmias cardíacas
AR024577A1 (es) Nuevos compuestos de bispidina utiles en el tratamiento de arritmias cardiacas
AR024392A1 (es) Nuevos compuestos de bispidina utiles en el tratamiento de arritmias cardiacas.
SE0002603D0 (sv) New compounds
SE9902596D0 (sv) Pharmaceutically active compounds
SE9802650D0 (sv) Compounds