DE60009069D1 - Bispidin-derivate zur behandlung von herzarrhythmien - Google Patents

Bispidin-derivate zur behandlung von herzarrhythmien

Info

Publication number
DE60009069D1
DE60009069D1 DE60009069T DE60009069T DE60009069D1 DE 60009069 D1 DE60009069 D1 DE 60009069D1 DE 60009069 T DE60009069 T DE 60009069T DE 60009069 T DE60009069 T DE 60009069T DE 60009069 D1 DE60009069 D1 DE 60009069D1
Authority
DE
Germany
Prior art keywords
treatment
heart arrhythmia
bispidine derivatives
bispidine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60009069T
Other languages
English (en)
Other versions
DE60009069T2 (de
Inventor
Annika Bjoere
Magnus Bjoersne
Torbjoern Halvarsson
Kurt-Juergen Hoffmann
Bertil Samuelsson
Gert Strandlund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE60009069D1 publication Critical patent/DE60009069D1/de
Application granted granted Critical
Publication of DE60009069T2 publication Critical patent/DE60009069T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60009069T 1999-06-16 2000-06-15 Bispidin-derivate zur behandlung von herzarrhythmien Expired - Fee Related DE60009069T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9902270A SE9902270D0 (sv) 1999-06-16 1999-06-16 Pharmaceutically active compounds
SE9902270 1999-06-16
PCT/SE2000/001253 WO2000076999A1 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias

Publications (2)

Publication Number Publication Date
DE60009069D1 true DE60009069D1 (de) 2004-04-22
DE60009069T2 DE60009069T2 (de) 2004-10-14

Family

ID=20416102

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60009069T Expired - Fee Related DE60009069T2 (de) 1999-06-16 2000-06-15 Bispidin-derivate zur behandlung von herzarrhythmien

Country Status (29)

Country Link
US (1) US6887881B1 (de)
EP (1) EP1192154B1 (de)
JP (1) JP2003502328A (de)
KR (1) KR20020010711A (de)
CN (1) CN1187350C (de)
AR (1) AR024393A1 (de)
AT (1) ATE261965T1 (de)
AU (1) AU762244B2 (de)
BR (1) BR0011673A (de)
CA (1) CA2384339A1 (de)
CZ (1) CZ20014494A3 (de)
DE (1) DE60009069T2 (de)
DK (1) DK1192154T3 (de)
EE (1) EE200100674A (de)
ES (1) ES2216912T3 (de)
HK (1) HK1045690A1 (de)
HU (1) HUP0202929A3 (de)
IL (1) IL146752A0 (de)
IS (1) IS6199A (de)
MX (1) MXPA01012925A (de)
NO (1) NO20016127L (de)
NZ (1) NZ516015A (de)
PL (1) PL353794A1 (de)
PT (1) PT1192154E (de)
SE (1) SE9902270D0 (de)
SK (1) SK18282001A3 (de)
TR (1) TR200103659T2 (de)
WO (1) WO2000076999A1 (de)
ZA (1) ZA200109800B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
AR030302A1 (es) * 2000-07-07 2003-08-20 Astrazeneca Ab Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios
IN2013DE02892A (de) 2013-09-30 2015-04-03 Council Scient Ind Res

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
ATA237287A (de) 1987-09-21 1993-02-15 Vaillant Gmbh Steuerung der temperatur des heizmediums einer umlaufheizung
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
WO1997017961A1 (en) 1995-11-13 1997-05-22 Smithkline Beecham Corporation Hemoregulatory compounds
SE9602263D0 (sv) * 1996-06-07 1996-06-07 Astra Ab New amino acid derivatives
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SE9803517D0 (sv) * 1998-10-15 1998-10-15 Astra Ab Pharmaceutical preparation
GB9823103D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
HUP0202214A3 (en) 1999-04-09 2002-12-28 Astrazeneca Ab Adamantane derivatives, preparation and use thereof
SE9901875D0 (sv) 1999-05-25 1999-05-25 Astra Pharma Prod Novel compounds
US20040229900A1 (en) * 1999-06-16 2004-11-18 Astrazeneca Ab Bispidine compounds useful in the treatment of cardiac arrythmias
SE9902271D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
SE0002603D0 (sv) * 2000-07-07 2000-07-07 Astrazeneca Ab New compounds

Also Published As

Publication number Publication date
IL146752A0 (en) 2002-07-25
AU762244B2 (en) 2003-06-19
ATE261965T1 (de) 2004-04-15
BR0011673A (pt) 2002-03-12
US6887881B1 (en) 2005-05-03
CN1187350C (zh) 2005-02-02
SE9902270D0 (sv) 1999-06-16
NO20016127D0 (no) 2001-12-14
PT1192154E (pt) 2004-07-30
CA2384339A1 (en) 2000-12-21
HUP0202929A2 (hu) 2003-02-28
HK1045690A1 (zh) 2002-12-06
KR20020010711A (ko) 2002-02-04
CZ20014494A3 (cs) 2002-05-15
EP1192154A1 (de) 2002-04-03
ZA200109800B (en) 2003-02-28
AR024393A1 (es) 2002-10-02
EE200100674A (et) 2003-02-17
IS6199A (is) 2001-12-14
CN1370164A (zh) 2002-09-18
DK1192154T3 (da) 2004-06-28
NZ516015A (en) 2003-06-30
AU5861100A (en) 2001-01-02
PL353794A1 (en) 2003-12-01
WO2000076999A1 (en) 2000-12-21
EP1192154B1 (de) 2004-03-17
JP2003502328A (ja) 2003-01-21
TR200103659T2 (tr) 2002-04-22
NO20016127L (no) 2002-02-12
ES2216912T3 (es) 2004-11-01
MXPA01012925A (es) 2002-07-30
DE60009069T2 (de) 2004-10-14
HUP0202929A3 (en) 2003-04-28
SK18282001A3 (sk) 2002-12-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee