SK92496A3 - Endothelin receptor antagonists - Google Patents

Endothelin receptor antagonists Download PDF

Info

Publication number
SK92496A3
SK92496A3 SK924-96A SK92496A SK92496A3 SK 92496 A3 SK92496 A3 SK 92496A3 SK 92496 A SK92496 A SK 92496A SK 92496 A3 SK92496 A3 SK 92496A3
Authority
SK
Slovakia
Prior art keywords
phenyl
methoxyphenyl
carboxymethyloxy
dimethoxyphenyl
methoxy
Prior art date
Application number
SK924-96A
Other languages
English (en)
Slovak (sk)
Inventor
Mathias Osswald
Dieter Darsch
Werner Mederski
Claudia Wilm
Claus Schmitges
Maria Christadler
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SK92496A3 publication Critical patent/SK92496A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK924-96A 1995-07-28 1996-07-16 Endothelin receptor antagonists SK92496A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19527568A DE19527568A1 (de) 1995-07-28 1995-07-28 Endothelin-Rezeptor-Antagonisten

Publications (1)

Publication Number Publication Date
SK92496A3 true SK92496A3 (en) 1997-07-09

Family

ID=7767990

Family Applications (1)

Application Number Title Priority Date Filing Date
SK924-96A SK92496A3 (en) 1995-07-28 1996-07-16 Endothelin receptor antagonists

Country Status (16)

Country Link
US (1) US5700807A (no)
EP (1) EP0755934A1 (no)
JP (1) JPH0940678A (no)
KR (1) KR970006305A (no)
AU (1) AU6060796A (no)
BR (1) BR9603164A (no)
CA (1) CA2182156A1 (no)
CZ (1) CZ219796A3 (no)
DE (1) DE19527568A1 (no)
HU (1) HUP9602054A3 (no)
MX (1) MX9603045A (no)
NO (1) NO963131L (no)
PL (1) PL315422A1 (no)
SK (1) SK92496A3 (no)
TW (1) TW367328B (no)
ZA (1) ZA966399B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291442B1 (en) 1998-02-03 2001-09-18 The General Hospital Corporation Pharmacological modulators of voltage-gated potassium ion channels
IL125659A (en) † 1998-08-05 2002-09-12 Cadent Ltd Method and device for three-dimensional simulation of a structure
US6638929B2 (en) 1999-12-29 2003-10-28 Wyeth Tricyclic protein kinase inhibitors
DE10155076A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Verwendung von Endothelin-Rezeptor-Antagonisten zur Behandlung von Tumorerkrankungen
ES2421511T3 (es) 2001-12-21 2013-09-03 X Ceptor Therapeutics Inc Moduladores de LXR
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
NZ534255A (en) * 2002-02-22 2007-06-29 Bayer Pharmaceuticals Corp Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders
AU2004268455B2 (en) * 2003-08-29 2009-12-17 Ono Pharmaceutical Co., Ltd. Compound capable of binding S1P receptor and pharmaceutical use thereof
WO2015088564A1 (en) * 2013-12-13 2015-06-18 Sunovion Pharmaceuticals Inc. P2x4 receptor modulating compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0339959A3 (en) * 1988-04-27 1991-03-20 Glaxo Group Limited Lactam derivatives
RU2086544C1 (ru) 1991-06-13 1997-08-10 Хоффманн-Ля Рош АГ Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина
ES2164054T3 (es) 1991-11-05 2002-02-16 Smithkline Beecham Corp Antagonistas de receptores de endotelina.
ZA939516B (en) 1992-12-22 1994-06-06 Smithkline Beecham Corp Endothelin receptor antagonists
EP0617001B1 (en) 1993-03-19 2000-01-26 Merck & Co. Inc. Phenoxyphenylacetic acid derivatives
US6075037A (en) * 1994-06-09 2000-06-13 Smithkline Beecham Corporation Endothelin receptor antagonists

Also Published As

Publication number Publication date
ZA966399B (en) 1997-02-19
CZ219796A3 (en) 1997-02-12
HU9602054D0 (en) 1996-09-30
CA2182156A1 (en) 1997-01-29
EP0755934A1 (en) 1997-01-29
NO963131D0 (no) 1996-07-26
NO963131L (no) 1997-01-29
HUP9602054A3 (en) 1998-07-28
TW367328B (en) 1999-08-21
KR970006305A (ko) 1997-02-19
HUP9602054A2 (en) 1997-11-28
AU6060796A (en) 1997-02-06
DE19527568A1 (de) 1997-01-30
BR9603164A (pt) 1998-05-05
JPH0940678A (ja) 1997-02-10
US5700807A (en) 1997-12-23
MX9603045A (es) 1997-01-31
PL315422A1 (en) 1997-02-03

Similar Documents

Publication Publication Date Title
CA1298836C (en) Imidazoquinoline antithrombogenic cardiotonic agents
KR100424045B1 (ko) 엔도델린수용체길항제
WO1998006722A1 (de) Thienopyrimidine
KR100484045B1 (ko) 기관지 치료용 벤조나프티리딘
SK280879B6 (sk) Tetracyklické deriváty, spôsob ich výroby, ich použitie a farmaceutické prostriedky s ich obsahom
WO1997019077A1 (de) Endothelin-rezeptor-antagonisten
CA2130859A1 (en) Thienopyrimidine derivatives, their production and use
SK92496A3 (en) Endothelin receptor antagonists
NO823026L (no) 2(1h)-pyridinoner og fremgangsmaate for deres fremstilling
NO179411B (no) Fremgangsmåte for fremstilling av pyrido[2,3-fÅ[1,4Åtiazepiner og pyrido[3,2-bÅ[1,5Åbenzotiazepiner
AU705959B2 (en) Endothelin receptor antagonists
HU194238B (en) Process for preparing ortho-condensed pyrrole derivatives and pharmaceuticals comprising the same
JPH10511118A (ja) エンドテリン受容体拮抗薬
JP2004504316A (ja) 新規６−ヘテロアリールフェナンスリジン
US5821256A (en) Endothelin receptor antagonists
US4524070A (en) Aminated derivatives of pyridazine substituted in 6 position by a heterocycle or an alicycle and compositions, said derivatives being active on the central nervous system
JP2969911B2 (ja) チオフェン化合物、その医薬用途およびその合成中間体
DE19711785A1 (de) Endothelin-Rezeptor-Antagonisten
EP0134535B1 (en) 1,6-naphthyridin derivatives useful as cardiotonics and preparation thereof
EP1599473B1 (en) Imidazo 4,5-b quinoline-derivatives and their use as no-synthase inhibitors
MXPA97004262A (es) Piridazinonas como antagonistas del receptor endotelial
SU1340587A3 (ru) Способ получени производных конденсированных бензопиронов или их фармацевтически приемлемых солей
US4604399A (en) 5-methyl(or ethyl)-1,6-naphthyridin-2(1H)-one 6-oxides, their preparation and the cardiotonic use thereof
JPH08277266A (ja) スピロ三環式芳香族スクシンイミド誘導体、並びにヒト及び動物の糖尿病合併症治療剤
PL94938B1 (no)