SK66497A3 - Bis-ortho-substituted benzoylguanidines, manufacturing process thereof, their us as a drug or diagnostic agent, as well as drug containing the same - Google Patents

Bis-ortho-substituted benzoylguanidines, manufacturing process thereof, their us as a drug or diagnostic agent, as well as drug containing the same Download PDF

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Publication number
SK66497A3
SK66497A3 SK664-97A SK66497A SK66497A3 SK 66497 A3 SK66497 A3 SK 66497A3 SK 66497 A SK66497 A SK 66497A SK 66497 A3 SK66497 A3 SK 66497A3
Authority
SK
Slovakia
Prior art keywords
group
carbon atoms
alkyl
independently
zero
Prior art date
Application number
SK664-97A
Other languages
English (en)
Slovak (sk)
Inventor
Udo Albus
Joachim Brendel
Heinz-Werner Kleemann
Hans Jochen Lang
Wolfgang Scholz
Jan-Robert Schwark
Andreas Weichert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SK66497A3 publication Critical patent/SK66497A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK664-97A 1996-05-28 1997-05-26 Bis-ortho-substituted benzoylguanidines, manufacturing process thereof, their us as a drug or diagnostic agent, as well as drug containing the same SK66497A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19621319A DE19621319A1 (de) 1996-05-28 1996-05-28 Bis-ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
SK66497A3 true SK66497A3 (en) 1997-12-10

Family

ID=7795458

Family Applications (1)

Application Number Title Priority Date Filing Date
SK664-97A SK66497A3 (en) 1996-05-28 1997-05-26 Bis-ortho-substituted benzoylguanidines, manufacturing process thereof, their us as a drug or diagnostic agent, as well as drug containing the same

Country Status (20)

Country Link
EP (1) EP0810207A1 (zh)
JP (1) JPH1081662A (zh)
KR (1) KR970074756A (zh)
CN (1) CN1170716A (zh)
AR (1) AR007497A1 (zh)
AU (1) AU2359897A (zh)
BR (1) BR9703326A (zh)
CA (1) CA2206198A1 (zh)
CZ (1) CZ161697A3 (zh)
DE (1) DE19621319A1 (zh)
HR (1) HRP970293A2 (zh)
HU (1) HUP9700953A3 (zh)
ID (1) ID16988A (zh)
IL (1) IL120908A0 (zh)
NO (1) NO972406L (zh)
NZ (1) NZ314900A (zh)
PL (1) PL318722A1 (zh)
SK (1) SK66497A3 (zh)
TR (1) TR199700423A2 (zh)
ZA (1) ZA974607B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19859727A1 (de) * 1998-12-23 2000-06-29 Aventis Pharma Gmbh Die Verwendung von Hemmern des Natrium-Wasserstoff-Austauschers zur Herstellung eines Medikaments zur Verhinderung von altersbedingten Organ-Dysfunktionen, altersbedingten Erkrankungen zur Lebensverlängerung
DE10001879A1 (de) * 2000-01-19 2001-07-19 Aventis Pharma Gmbh Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CA2513575A1 (en) 2003-01-17 2004-08-05 Threshold Pharmaceuticals, Inc. Treatment of benign prostatic hyperplasia using energolytic agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0556673B1 (de) * 1992-02-15 1997-09-17 Hoechst Aktiengesellschaft Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4417004A1 (de) * 1994-05-13 1995-11-16 Hoechst Ag Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4422685A1 (de) * 1994-06-29 1996-01-04 Hoechst Ag Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4432101A1 (de) * 1994-09-09 1996-03-14 Hoechst Ag Aminosäure-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4432106A1 (de) * 1994-09-09 1996-03-14 Hoechst Ag Mit Heterocyclen-N-Oxid-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum, sie enthaltendes Medikament sowie Zwischenprodukte zu ihrer Herstellung

Also Published As

Publication number Publication date
NO972406D0 (no) 1997-05-27
NO972406L (no) 1997-12-01
ZA974607B (en) 1997-11-28
TR199700423A2 (xx) 1997-12-21
DE19621319A1 (de) 1997-12-04
MX9703871A (es) 1997-11-29
BR9703326A (pt) 1998-09-22
AU2359897A (en) 1997-12-04
EP0810207A1 (de) 1997-12-03
CA2206198A1 (en) 1997-11-28
PL318722A1 (en) 1997-12-08
HRP970293A2 (en) 1998-04-30
JPH1081662A (ja) 1998-03-31
HUP9700953A2 (hu) 1998-03-02
AR007497A1 (es) 1999-11-10
CZ161697A3 (cs) 1998-06-17
NZ314900A (en) 1998-02-26
CN1170716A (zh) 1998-01-21
HUP9700953A3 (en) 1998-04-28
HU9700953D0 (en) 1997-07-28
IL120908A0 (en) 1997-09-30
KR970074756A (ko) 1997-12-10
ID16988A (id) 1997-11-27

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