SK5942003A3 - Substituted derivatives of aminofuran-2-yl-acetic acid and aminothien-2-yl-acetic acid and the use thereof for treating migraines and pain - Google Patents

Substituted derivatives of aminofuran-2-yl-acetic acid and aminothien-2-yl-acetic acid and the use thereof for treating migraines and pain Download PDF

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Publication number
SK5942003A3
SK5942003A3 SK594-2003A SK5942003A SK5942003A3 SK 5942003 A3 SK5942003 A3 SK 5942003A3 SK 5942003 A SK5942003 A SK 5942003A SK 5942003 A3 SK5942003 A3 SK 5942003A3
Authority
SK
Slovakia
Prior art keywords
carbon atoms
furan
methyl
alkyl
group
Prior art date
Application number
SK594-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Corinna Sundermann
Werner Englberger
Michael Przewosny
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of SK5942003A3 publication Critical patent/SK5942003A3/sk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
SK594-2003A 2000-11-30 2001-11-28 Substituted derivatives of aminofuran-2-yl-acetic acid and aminothien-2-yl-acetic acid and the use thereof for treating migraines and pain SK5942003A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10059864A DE10059864A1 (de) 2000-11-30 2000-11-30 Substituierte Amino-furan-2-yl-essigsäure- und Amino-thien-2-yl-essigsäure-Derivate
PCT/EP2001/013910 WO2002044171A1 (de) 2000-11-30 2001-11-28 Substituierte amino-furan-2-yl-essigsaure- und amino-thien-2-yl-essigsaure-derivate und ihre verwendung zur behandlung von migraine bzw. schmerz

Publications (1)

Publication Number Publication Date
SK5942003A3 true SK5942003A3 (en) 2003-11-04

Family

ID=7665508

Family Applications (1)

Application Number Title Priority Date Filing Date
SK594-2003A SK5942003A3 (en) 2000-11-30 2001-11-28 Substituted derivatives of aminofuran-2-yl-acetic acid and aminothien-2-yl-acetic acid and the use thereof for treating migraines and pain

Country Status (30)

Country Link
US (1) US6797712B2 (es)
EP (1) EP1341786B9 (es)
JP (1) JP4340063B2 (es)
KR (1) KR20030055334A (es)
CN (1) CN1326854C (es)
AR (1) AR035658A1 (es)
AT (1) ATE418552T1 (es)
AU (2) AU2073502A (es)
BR (1) BR0115883A (es)
CA (1) CA2430280A1 (es)
CY (1) CY1108871T1 (es)
CZ (1) CZ20031509A3 (es)
DE (2) DE10059864A1 (es)
DK (1) DK1341786T3 (es)
EC (1) ECSDI034631S (es)
ES (1) ES2320198T3 (es)
HK (1) HK1059080A1 (es)
HU (1) HUP0303041A3 (es)
IL (2) IL156139A0 (es)
MX (1) MXPA03004303A (es)
NO (1) NO20032340L (es)
NZ (1) NZ526554A (es)
PE (1) PE20020599A1 (es)
PL (1) PL362978A1 (es)
PT (1) PT1341786E (es)
RU (1) RU2003117703A (es)
SI (1) SI1341786T1 (es)
SK (1) SK5942003A3 (es)
WO (1) WO2002044171A1 (es)
ZA (1) ZA200305009B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794506B2 (en) * 2000-07-21 2004-09-21 Elan Pharmaceuticals, Inc. 3-(heteroaryl) alanine derivatives-inhibitors of leukocyte adhesion mediated by VLA-4
DE10125145A1 (de) 2001-05-22 2002-11-28 Gruenenthal Gmbh Substituierte C-Furan-2-yl-methylamin- und C-Thiophen-2-yl-methylamin-Derivate
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
DE10306203A1 (de) * 2003-02-13 2004-08-26 Grünenthal GmbH Arzneimittel enthaltend substituierte 2-Heteroaryl-Aminoessigsäure-Verbindungen
DE10306202A1 (de) * 2003-02-13 2004-08-26 Grünenthal GmbH Arzneimittel enthaltend substituierte 2-Aryl-Aminoessigsäure-Verbindungen und/oder substituierte 2-Heteroaryl-Aminoessigsäure-Verbindungen
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
US10144736B2 (en) * 2006-07-20 2018-12-04 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
CU20180011A7 (es) 2015-03-04 2018-06-05 Gilead Sciences Inc Composiciones farmacéuticas que comprenden compuestos derivados de diaminopirido (3,2-d) como moduladores de receptor de tipo toll
CA3035346A1 (en) 2016-09-02 2018-03-08 Gilead Sciences, Inc. Toll like receptor modulator compounds
ES2826748T3 (es) 2016-09-02 2021-05-19 Gilead Sciences Inc Derivados de 4,6-diamino-pirido[3,2-d]pirimidina como moduladores de receptores de tipo Toll
TWI751516B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法
CN115382297B (zh) * 2022-04-12 2023-10-31 江阴市华思诚无纺布有限公司 熔体直纺双组分pet纺粘液体过滤材料及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739048D1 (de) * 1996-06-28 2008-11-27 Univ Southern California Verfahren zur synthese von aminen und aminosäuren mit organoborverbindungen
US6441237B1 (en) 1999-02-20 2002-08-27 Boehringer Ingelheim Pharma Kg Substituted 3-phenoxy- and 3-phenylalkyloxy-2-phenyl-propylamines
DE19907385A1 (de) * 1999-02-20 2000-08-24 Boehringer Ingelheim Pharma Neue substituierte 3-Phenoxy- und 3-Phenylalkyloxy-2-phenyl-propylamine
GB0030304D0 (en) * 2000-12-13 2001-01-24 Lilly Co Eli Compounds

Also Published As

Publication number Publication date
BR0115883A (pt) 2003-12-02
JP4340063B2 (ja) 2009-10-07
PT1341786E (pt) 2009-03-31
CA2430280A1 (en) 2002-06-06
HK1059080A1 (en) 2004-06-18
RU2003117703A (ru) 2004-12-10
EP1341786B1 (de) 2008-12-24
US6797712B2 (en) 2004-09-28
JP2004526675A (ja) 2004-09-02
NZ526554A (en) 2005-02-25
PL362978A1 (en) 2004-11-02
EP1341786B9 (de) 2009-08-05
ES2320198T3 (es) 2009-05-20
CN1326854C (zh) 2007-07-18
IL156139A (en) 2007-08-19
US20040030156A1 (en) 2004-02-12
HUP0303041A2 (hu) 2003-12-29
HUP0303041A3 (en) 2007-06-28
CY1108871T1 (el) 2014-07-02
ATE418552T1 (de) 2009-01-15
EP1341786A1 (de) 2003-09-10
AR035658A1 (es) 2004-06-23
CN1478089A (zh) 2004-02-25
ECSDI034631S (es) 2003-07-25
PE20020599A1 (es) 2002-08-10
IL156139A0 (en) 2003-12-23
CZ20031509A3 (cs) 2003-09-17
NO20032340L (no) 2003-07-21
ZA200305009B (en) 2004-08-18
DE10059864A1 (de) 2002-06-13
AU2073502A (en) 2002-06-11
WO2002044171A1 (de) 2002-06-06
DE50114605D1 (de) 2009-02-05
KR20030055334A (ko) 2003-07-02
AU2002220735B2 (en) 2007-05-10
DK1341786T3 (da) 2009-04-20
MXPA03004303A (es) 2003-08-19
NO20032340D0 (no) 2003-05-23
SI1341786T1 (sl) 2009-04-30

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