SK40395A3 - Pyridoindolobenzodiazepines and derivatives as antipsychotics - Google Patents

Pyridoindolobenzodiazepines and derivatives as antipsychotics Download PDF

Info

Publication number
SK40395A3
SK40395A3 SK403-95A SK40395A SK40395A3 SK 40395 A3 SK40395 A3 SK 40395A3 SK 40395 A SK40395 A SK 40395A SK 40395 A3 SK40395 A3 SK 40395A3
Authority
SK
Slovakia
Prior art keywords
carbon atoms
alkyl
compound according
cycloalkyl
mammal
Prior art date
Application number
SK403-95A
Other languages
English (en)
Slovak (sk)
Inventor
Partnasarathi Rajagopalan
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of SK40395A3 publication Critical patent/SK40395A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK403-95A 1992-07-29 1993-07-23 Pyridoindolobenzodiazepines and derivatives as antipsychotics SK40395A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/921,051 US5321023A (en) 1992-07-29 1992-07-29 Pyridoindolobenzodiazepines and derivatives as antipsychotics
PCT/US1993/006823 WO1994003455A1 (en) 1992-07-29 1993-07-23 Pyridoindolobenzodiazepines and derivatives as antipsychotics

Publications (1)

Publication Number Publication Date
SK40395A3 true SK40395A3 (en) 1995-12-06

Family

ID=25444846

Family Applications (1)

Application Number Title Priority Date Filing Date
SK403-95A SK40395A3 (en) 1992-07-29 1993-07-23 Pyridoindolobenzodiazepines and derivatives as antipsychotics

Country Status (22)

Country Link
US (1) US5321023A (no)
EP (1) EP0652878A1 (no)
JP (1) JPH08500579A (no)
KR (1) KR950702562A (no)
CN (1) CN1100424A (no)
AU (1) AU4685393A (no)
BR (1) BR9306896A (no)
CA (1) CA2141332A1 (no)
CZ (1) CZ19895A3 (no)
FI (1) FI950303A (no)
HR (1) HRP931082A2 (no)
HU (1) HUT69393A (no)
IL (1) IL106352A0 (no)
MX (1) MX9304552A (no)
NO (1) NO950327L (no)
NZ (1) NZ254650A (no)
PL (1) PL307231A1 (no)
RU (1) RU95107706A (no)
SK (1) SK40395A3 (no)
TW (1) TW260670B (no)
WO (1) WO1994003455A1 (no)
ZA (1) ZA935486B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19546297C2 (de) 1995-12-12 2003-12-04 Temic Bayern Chem Airbag Gmbh Airbagsystem mit variablem Auslösezeitpunkt
US8367655B2 (en) * 2009-07-03 2013-02-05 Daya Drug Discoveries, Inc. Pyridoindolobenzox—and thiazepine derivatives and uses thereof
EP2964331B1 (en) * 2013-03-04 2019-08-28 Daya CNS LLC Pentacyclic pyridoindolo[b,e]azepine derivatives and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3373168A (en) * 1964-06-02 1968-03-12 Hoffmann La Roche Certain benzazepinoxyridoindole compounds and their preparation
US3457271A (en) * 1964-06-02 1969-07-22 Hoffmann La Roche 11-lower alkyl-hexahydro-1-benzazepino (3,2,1-h,i)pyrido(4,3-b)indole
US3764684A (en) * 1971-08-11 1973-10-09 M Finizio Novel indolobenzazepine derivatives, useful as tranquilizers
US3790675A (en) * 1972-04-19 1974-02-05 Endo Lab Certain indolobenzazepine derivatives as analgesics
US3932650A (en) * 1973-01-22 1976-01-13 E. I. Du Pont De Nemours & Company Trans-octahydropyridoindolobenzazepines as central nervous system depressants
US3890327A (en) * 1973-05-11 1975-06-17 Du Pont Trans-1,2,3,4,4a,8,9,14a-octahydropyrido(r',3':2,3)indolo(1,7-ab)+8 1)benzazepine
US3983123A (en) * 1973-01-22 1976-09-28 Endo Laboratories, Inc. Trans-octahydropyridoindolobenzazepines
CA1026331A (en) * 1973-12-06 1978-02-14 Joel G. Berger Substituted indolobenzazepines
US4438120A (en) * 1982-11-12 1984-03-20 E. I. Du Pont De Nemours & Company Pyridoindolobenzodiazepine tranquilizers

Also Published As

Publication number Publication date
FI950303A0 (fi) 1995-01-24
KR950702562A (ko) 1995-07-29
CA2141332A1 (en) 1994-02-17
RU95107706A (ru) 1997-03-20
EP0652878A1 (en) 1995-05-17
WO1994003455A1 (en) 1994-02-17
BR9306896A (pt) 1998-12-08
IL106352A0 (en) 1993-11-15
HUT69393A (en) 1995-09-28
MX9304552A (es) 1994-05-31
NZ254650A (en) 1996-03-26
HRP931082A2 (en) 1997-06-30
NO950327D0 (no) 1995-01-27
PL307231A1 (en) 1995-05-15
NO950327L (no) 1995-01-27
JPH08500579A (ja) 1996-01-23
ZA935486B (en) 1995-01-30
US5321023A (en) 1994-06-14
FI950303A (fi) 1995-01-24
HU9500193D0 (en) 1995-03-28
CZ19895A3 (en) 1995-11-15
TW260670B (no) 1995-10-21
AU4685393A (en) 1994-03-03
CN1100424A (zh) 1995-03-22

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