SK3872002A3 - Therapeutic quinazoline derivatives, method for the preparation thereof and pharmaceutical composition comprising same - Google Patents

Therapeutic quinazoline derivatives, method for the preparation thereof and pharmaceutical composition comprising same Download PDF

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Publication number
SK3872002A3
SK3872002A3 SK387-2002A SK3872002A SK3872002A3 SK 3872002 A3 SK3872002 A3 SK 3872002A3 SK 3872002 A SK3872002 A SK 3872002A SK 3872002 A3 SK3872002 A3 SK 3872002A3
Authority
SK
Slovakia
Prior art keywords
group
alkyl
carbon atoms
moiety
alkoxy
Prior art date
Application number
SK387-2002A
Other languages
English (en)
Slovak (sk)
Inventor
Andrew Austen Mortlock
Nicholas John Keen
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SK3872002A3 publication Critical patent/SK3872002A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK387-2002A 1999-09-21 2000-09-19 Therapeutic quinazoline derivatives, method for the preparation thereof and pharmaceutical composition comprising same SK3872002A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9922171.5A GB9922171D0 (en) 1999-09-21 1999-09-21 Chemical compounds
PCT/GB2000/003593 WO2001021597A1 (en) 1999-09-21 2000-09-19 Therapeutic quinazoline derivatives

Publications (1)

Publication Number Publication Date
SK3872002A3 true SK3872002A3 (en) 2002-12-03

Family

ID=10861217

Family Applications (1)

Application Number Title Priority Date Filing Date
SK387-2002A SK3872002A3 (en) 1999-09-21 2000-09-19 Therapeutic quinazoline derivatives, method for the preparation thereof and pharmaceutical composition comprising same

Country Status (24)

Country Link
US (1) US7235559B1 (ja)
EP (1) EP1218355A1 (ja)
JP (1) JP2003509500A (ja)
KR (1) KR20020030123A (ja)
CN (1) CN1391563A (ja)
AR (1) AR025735A1 (ja)
AU (1) AU762697B2 (ja)
BG (1) BG106526A (ja)
BR (1) BR0014137A (ja)
CA (1) CA2384296A1 (ja)
CO (1) CO5200783A1 (ja)
CZ (1) CZ20021008A3 (ja)
EE (1) EE200200118A (ja)
GB (1) GB9922171D0 (ja)
HK (1) HK1046685A1 (ja)
HU (1) HUP0300205A3 (ja)
IL (1) IL148496A0 (ja)
IS (1) IS6310A (ja)
NO (1) NO20021400L (ja)
PL (1) PL354870A1 (ja)
SK (1) SK3872002A3 (ja)
TR (1) TR200200717T2 (ja)
WO (1) WO2001021597A1 (ja)
ZA (1) ZA200202232B (ja)

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JP2002293773A (ja) * 2001-03-30 2002-10-09 Sumika Fine Chemicals Co Ltd キナゾリン誘導体の製造方法
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CN1627944A (zh) 2002-01-17 2005-06-15 神经能质公司 取代的喹唑啉－4－基胺类似物作为辣椒辣素调节剂
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Also Published As

Publication number Publication date
ZA200202232B (en) 2003-08-27
WO2001021597A1 (en) 2001-03-29
TR200200717T2 (tr) 2002-06-21
HK1046685A1 (zh) 2003-01-24
IL148496A0 (en) 2002-09-12
CN1391563A (zh) 2003-01-15
HUP0300205A3 (en) 2003-08-28
JP2003509500A (ja) 2003-03-11
US7235559B1 (en) 2007-06-26
BR0014137A (pt) 2002-05-21
CZ20021008A3 (cs) 2002-06-12
AU7301900A (en) 2001-04-24
HUP0300205A2 (en) 2003-05-28
BG106526A (en) 2002-10-31
EE200200118A (et) 2003-04-15
CA2384296A1 (en) 2001-03-29
CO5200783A1 (es) 2002-09-27
KR20020030123A (ko) 2002-04-22
IS6310A (is) 2002-03-19
GB9922171D0 (en) 1999-11-17
AR025735A1 (es) 2002-12-11
AU762697B2 (en) 2003-07-03
PL354870A1 (en) 2004-03-08
EP1218355A1 (en) 2002-07-03
NO20021400L (no) 2002-05-06
NO20021400D0 (no) 2002-03-20

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