SK3782002A3 - 4-amino-1-aryl-1,5-dihydro-pyrrole-2-one with anti-convulsive and anxiolytic properties and a method for producing the same - Google Patents

4-amino-1-aryl-1,5-dihydro-pyrrole-2-one with anti-convulsive and anxiolytic properties and a method for producing the same Download PDF

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Publication number
SK3782002A3
SK3782002A3 SK378-2002A SK3782002A SK3782002A3 SK 3782002 A3 SK3782002 A3 SK 3782002A3 SK 3782002 A SK3782002 A SK 3782002A SK 3782002 A3 SK3782002 A3 SK 3782002A3
Authority
SK
Slovakia
Prior art keywords
dihydro
pyrrol
morpholin
group
dihydropyrrol
Prior art date
Application number
SK378-2002A
Other languages
English (en)
Slovak (sk)
Inventor
Thomas Arnold
Klaus Unverferth
Hans-Joachim Lankau
Angelika Rostock
Christine Tober
Chris Runfeldt
Reni Bartsch
Original Assignee
Dresden Arzneimittel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dresden Arzneimittel filed Critical Dresden Arzneimittel
Publication of SK3782002A3 publication Critical patent/SK3782002A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK378-2002A 1999-09-16 2000-09-02 4-amino-1-aryl-1,5-dihydro-pyrrole-2-one with anti-convulsive and anxiolytic properties and a method for producing the same SK3782002A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19944332A DE19944332A1 (de) 1999-09-16 1999-09-16 Antikonvulsiv und anxiolytisch wirkende 4-Amino-1-aryl-1,5-dihydro-pyrrol-2-one und Verfahren zu deren Herstellung
PCT/EP2000/008572 WO2001019793A1 (de) 1999-09-16 2000-09-02 Antikonvulsiv und anxiolytisch wirkende 4-amino-1-aryl-1,5-dihydro-pyrrol-2-one und verfahren zu deren darstellung

Publications (1)

Publication Number Publication Date
SK3782002A3 true SK3782002A3 (en) 2002-07-02

Family

ID=7922190

Family Applications (1)

Application Number Title Priority Date Filing Date
SK378-2002A SK3782002A3 (en) 1999-09-16 2000-09-02 4-amino-1-aryl-1,5-dihydro-pyrrole-2-one with anti-convulsive and anxiolytic properties and a method for producing the same

Country Status (20)

Country Link
US (1) US6500821B1 (es)
EP (1) EP1212297A1 (es)
JP (1) JP2003509407A (es)
KR (1) KR20020027657A (es)
CN (1) CN1374948A (es)
AR (1) AR025700A1 (es)
AU (1) AU7283000A (es)
BG (1) BG106437A (es)
BR (1) BR0013961A (es)
CA (1) CA2317257A1 (es)
CZ (1) CZ2002915A3 (es)
DE (1) DE19944332A1 (es)
EE (1) EE200200137A (es)
HU (1) HUP0202607A3 (es)
IL (1) IL147808A0 (es)
MX (1) MXPA02001370A (es)
NO (1) NO20021143L (es)
SK (1) SK3782002A3 (es)
TR (1) TR200200678T2 (es)
WO (1) WO2001019793A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106008304B (zh) * 2016-05-18 2018-07-17 湖北科技学院 一种1,3-二氢吡咯-2-酮类化合物及其合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH543504A (de) * 1971-03-25 1973-10-31 Lonza Ag Verfahren zur Herstellung 1-substituierter 4-Aminopyrrolin-3-one-(2)
US4511568A (en) 1982-05-12 1985-04-16 Ici Americas Inc. CNS-Depressant pyrazolopyridines

Also Published As

Publication number Publication date
HUP0202607A3 (en) 2003-05-28
AR025700A1 (es) 2002-12-11
CA2317257A1 (en) 2001-03-16
CZ2002915A3 (cs) 2002-06-12
DE19944332A1 (de) 2001-03-22
NO20021143D0 (no) 2002-03-07
US6500821B1 (en) 2002-12-31
BR0013961A (pt) 2002-05-21
AU7283000A (en) 2001-04-17
BG106437A (bg) 2002-09-30
WO2001019793A1 (de) 2001-03-22
HUP0202607A2 (hu) 2002-12-28
NO20021143L (no) 2002-03-07
EE200200137A (et) 2003-04-15
IL147808A0 (en) 2002-08-14
TR200200678T2 (tr) 2002-07-22
JP2003509407A (ja) 2003-03-11
EP1212297A1 (de) 2002-06-12
CN1374948A (zh) 2002-10-16
KR20020027657A (ko) 2002-04-13
MXPA02001370A (es) 2004-09-10

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